Results 281 to 290 of about 156,001 (374)

Top‐Down Proteomics Study of Aging and Sexual Dimorphism of Zebrafish Brains

Journal of Mass Spectrometry, Volume 61, Issue 1, January 2026.
ABSTRACT Aging significantly impacts brain function and increases susceptibility to neurodegenerative diseases, with notable sex dimorphism observed in aging‐related dementia, such as Alzheimer's disease. To better understand the molecular mechanisms of aging and dementia, it is essential to globally and accurately characterize biomolecules (e.g ...
Mehrdad Falamarzi Askarani, William Poulos, Maryam Rahimzadeh Dashtaki, Seyed Amirhossein Sadeghi, Jose B. Cibelli, Fei Fang, Liangliang Sun   +6 more
wiley   +1 more source

Mechanistic models of asymmetric hand-over-hand translocation and nucleosome navigation by CMG helicase. [PDF]

Nat Commun
Nagae F, Murata Y, Yamauchi M, Takada S, Terakawa T.   +4 more
europepmc   +1 more source

Circular RNAs: Epigenetic Puppeteers Pulling the Strings of Cancer Pathogenesis

Medicine Bulletin, Volume 2, Issue 1, Page 124-136, January 2026.
ABSTRACT Circular RNAs (circRNAs), a unique class of endogenous noncoding RNAs characterized by their covalently closed loop structure, have emerged as pivotal players in cancer biology due to their exceptional stability, tissue‐specific expression, and diverse regulatory functions.
Yimao Wu, Zichang Chen, Junying Lee, Gokhan Zengin, Meng‐Yao Li   +4 more
wiley   +1 more source

Feed-forward loops by NR5A2 ensure robust gene activation during pre-implantation development. [PDF]

Development
Kobayashi W, Ruangroengkulrith S, Arslantas EN, Mohanan A, Tachibana K.   +4 more
europepmc   +1 more source

Chromatin fiber invasion and nucleosome displacement by the Rap1 transcription factor_Figure5e_1

, 2019
Maxime Mivelaz, Anne-Marinette Cao, Slawomir Kubik, Sevil Zencir, Ruud Hovius, Iuliia Boichenko, Anna Maria Stachowicz, Christoph F. Kurat, David Shore, Beat Fierz   +9 more
openalex   +1 more source

High‐Quality Genome Assembly of Diplocarpon coronariae Unveils LTR Retrotransposon‐Driven Structural Dynamics in Fungi Evolution

Molecular Ecology Resources, Volume 26, Issue 1, January 2026.
ABSTRACT Long terminal repeat retrotransposons (LTR‐RTs) are recognised as a significant evolutionary force capable of shaping the structure and function of the genomes in eukaryotes, including animals, plants, and fungi. However, much remains largely unknown about how LTR‐RTs influence the evolution of fungi at the chromosomal level.
Chengyu Gao, Xiao Liu, Binsen Zhao, Hao Feng, Lili Huang   +4 more
wiley   +1 more source

Controls of Nucleosome Positioning in the Human Genome

, 2012
Daniel J. Gaffney, Graham McVicker, Athma A. Pai, Yvonne Fondufe‐Mittendorf, Noah Lewellen, Katelyn Michelini, Jonathan Widom, Yoav Gilad, Jonathan K. Pritchard   +8 more
openalex   +2 more sources

Preliminary Evidence for Increased Histone Succinylation as a Potential Epigenetic Marker for Longevity

Aging Cell, Volume 25, Issue 1, January 2026.
Elevated histone succinylation distinguishes offspring of long‐lived individuals and aligns with enhanced nuclear functions, while succinate supplementation selectively improves motor performance in aging mice, suggesting succinylation as a candidate protective epigenetic feature of longevity.
Stephanie Stransky, Sarah Graff, Kai Mao, Derek M. Huffman, Sofiya Milman, Nir Barzilai, Simone Sidoli   +6 more
wiley   +1 more source

Distinct roles of histone H2B ubiquitination at promoters and coding regions of Pol II-transcribed stress genes. [PDF]

Genome Biol
Barrios R, Vega M, Gracia-Domingo R, Boronat S, García-Santamarina S, Tanny JC, Ayté J, Hidalgo E.   +7 more
europepmc   +1 more source

Reviewer #1 (Public review): A genome-wide nucleosome-resolution map of promoter-centered interactions in human cells corroborates the enhancer-promoter looping model

Arkadiy K Golov, Alexey A Gavrilov, Noam Kaplan, Sergey V Razin   +3 more
openalex   +1 more source