Results 291 to 300 of about 141,257 (371)
Investigation of DNA Damage and Apoptosis in Bovine Ocular Squamous Cell Carcinoma
Veterinary Medicine and Science, Volume 11, Issue 4, July 2025.This is the first study to report an increase in double‐stranded DNA breaks in BOSCC, an important tumoural disease of cattle. In this study, where an increase in DNA oxidation was also shown, we determined that apoptotic defence reactions were reduced, contributing to the pathogenesis.
Muhammet Bahaeddin Dörtbudak +1 more
wiley +1 more source
Twenty-Five Years of the Nucleosome, Fundamental Particle of the Eukaryote Chromosome
Cell, 1999 R. Kornberg, Y. Lorch
semanticscholar +1 more source
Aging Cell, Volume 24, Issue 7, July 2025.Expression of HIRA in embryonic melanoblasts is required for proper epigenetic programing and lineage differentiation. Although HIRA deficiency results in a mild phenotype at birth and young adulthood, the melanocytic lineage is sensitive to proliferative challenge, prone to loss of stem cells and dramatically accelerated hair greying in later life ...
Farah Jaber‐Hijazi +20 more
wiley +1 more source
Consecutive low-frequency shifts in A/T content denote nucleosome positions across microeukaryotes. [PDF]
iScienceMondo SJ +17 more
europepmc +1 more source
Insights Into Cockayne Syndrome Type B: What Underlies Its Pathogenesis?
Aging Cell, Volume 24, Issue 7, July 2025.Cockayne Syndrome complementation group B (CS‐B) is a highly debilitating progeroid syndrome that often culminates in the death of patients before adulthood. This review explores the pathogenesis of CS‐B and proposes that a combination of DNA damage accumulation, transcriptional dysregulation, and mitochondrial dysfunction is its underlying cause ...
Ricardo Afonso‐Reis +3 more
wiley +1 more source
Native nucleosomes intrinsically encode genome organization principles. [PDF]
NaturePark S +14 more
europepmc +1 more source
Pathological significance of intranuclear structures in liver biopsy samples
Hepatology Research, Volume 55, Issue 7, Page 1065-1074, July 2025.Schematic representation of the potential significance of three distinct nuclear structures. Glycogenated nuclei reflects excessive glycogen accumulation in the hepatocytes. Nucleoplasmic lipid droplets form in the nucleus during hepatocyte injury. Cytoplasmic lipid droplets in the nucleoplasmic reticulum are suppressed when there is excessive fat ...
Norihiro Imai +15 more
wiley +1 more source
Preferential and asymmetric interaction of linker histones with 5S DNA in the nucleosome.
, 1993 Jeffrey J. Hayes, Alan P. Wolffe
openalex +1 more source