Results 341 to 350 of about 156,001 (374)

Structure of human chromatin-remodelling PBAF complex bound to a nucleosome

Nature, 2022
Junjie Yuan, Kangjing Chen, Wenbo Zhang, Zhucheng Chen   +3 more
semanticscholar   +1 more source

Remodeling of Individual Nucleosomes in Nucleosome Arrays

Adenosin triphosphate (ATP)-dependent nucleosome remodeling factors sculpt the nucleosomal landscape of eukaryotic chromatin. They deposit, evict, or reposition nucleosomes along DNA in a process termed nucleosome sliding. Remodeling has traditionally been analyzed using mononucleosomes as a model substrate.
Petra, Vizjak, Nicola, Hepp, Felix, Mueller-Planitz   +2 more
openaire   +2 more sources

Structure and dynamics of the yeast SWR1-nucleosome complex

Science, 2018
From DNA unwrapping to histone exchange The yeast SWR1 complex, a member of the INO80 family of nucleosome remodelers, exchanges the H2A-H2B histone dimer for the Htz1 variant–containing dimer.
O. Willhoft, Mohamed Ghoneim, C. Lin, E.Y.D. Chua, M. Wilkinson, Y. Chaban, Rafael Ayala, E. A. Mccormack, Lorraine Ocloo, D. Rueda, D. Wigley   +10 more
semanticscholar   +1 more source

Apoptosis and nucleosomes

Lupus, 2002
Drs Berden and Koutouzov presented evidence that nucleosomes are antigens in lupus pathogenesis and that apoptotic cells are the source of nucleosomes. Berden's group measured persistence of circulating nucleosomes and nucleosome–antibody complexes in autoimmune mice and demonstrated nucleosomaldepositionin skin of SLE patientsas well as in renal ...
B D, Stollar, F, Stephenson
openaire   +2 more sources

Packaging without nucleosomes

Science, 2017
Chromosomes The fundamental compaction of DNA in chromosomes is thought to start with the wrapping of DNA around nucleosomes, but is nucleosome wrapping required for the condensation of mitotic chromosomes? Shintomi et al. combined Xenopus egg extracts and mouse sperm nuclei and found that chromosome-like structures could be assembled in the near ...
openaire   +2 more sources

Structural mechanism of cGAS inhibition by the nucleosome

Nature, 2020
G. Pathare, Alexiane C. Decout, S. Glück, S. Cavadini, Kristina A Makasheva, R. Hovius, G. Kempf, Joscha Weiss, Zuzanna Kozicka, Baptiste Guey, Pauline Mélénec, B. Fierz, N. Thomä, A. Ablasser   +13 more
semanticscholar   +1 more source

RNA polymerase II elongation complex bound with Elf1 and Spt4/5, stalled at SHL(-5) of the nucleosome

, 2019
RNA polymerase II (RNAPII) transcribes chromosomal DNA that contains multiple nucleosomes. The nucleosome forms transcriptional barriers, and nucleosomal transcription requires several additional factors in vivo.
H. Ehara, T. Kujirai, Y. Fujino, M. Shirouzu, H. Kurumizaka, S. Sekine   +5 more
semanticscholar   +1 more source

Crystal structure of the nucleosome core particle at 2.8 Å resolution

Nature, 1997
K. Luger, A. Mäder, R. K. Richmond, D. Sargent, T. Richmond   +4 more
semanticscholar   +1 more source

New DNA sequence rules for high affinity binding to histone octamer and sequence-directed nucleosome positioning.

Journal of Molecular Biology, 1998
P. Lowary, J. Widom
semanticscholar   +1 more source

Beads on a string—nucleosome array arrangements and folding of the chromatin fiber

Nature Structural & Molecular Biology, 2020
Sandro Baldi, Philipp Korber, P. Becker
semanticscholar   +1 more source