Results 351 to 360 of about 141,257 (371)
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Clinica Chimica Acta, 2006
The nucleosome is a large protein-nucleic acid complex involved in DNA packing and in controlling genetic information. Under circumstances described below, this component, normally sequestered in the cell nucleus, is released into the extracellular milieu and then is easily accessible to cells of the immune system.
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The nucleosome is a large protein-nucleic acid complex involved in DNA packing and in controlling genetic information. Under circumstances described below, this component, normally sequestered in the cell nucleus, is released into the extracellular milieu and then is easily accessible to cells of the immune system.
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Structure of human chromatin-remodelling PBAF complex bound to a nucleosome
Nature, 2022Junjie Yuan +3 more
semanticscholar +1 more source
, 2019
RNA polymerase II (RNAPII) transcribes chromosomal DNA that contains multiple nucleosomes. The nucleosome forms transcriptional barriers, and nucleosomal transcription requires several additional factors in vivo.
H. Ehara +5 more
semanticscholar +1 more source
RNA polymerase II (RNAPII) transcribes chromosomal DNA that contains multiple nucleosomes. The nucleosome forms transcriptional barriers, and nucleosomal transcription requires several additional factors in vivo.
H. Ehara +5 more
semanticscholar +1 more source
2019
Genomic nucleosome positions determine DNA accessibility to regulatory molecules, and thus modulate gene expression. Nucleosome positioning can be characterised by the location of the nucleosome centres, average occupancy landscapes, the stability of individual nucleosomes, and integral parameters such as the nucleosome repeat length.
Teif, Vladimir B +1 more
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Genomic nucleosome positions determine DNA accessibility to regulatory molecules, and thus modulate gene expression. Nucleosome positioning can be characterised by the location of the nucleosome centres, average occupancy landscapes, the stability of individual nucleosomes, and integral parameters such as the nucleosome repeat length.
Teif, Vladimir B +1 more
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Remodeling of Individual Nucleosomes in Nucleosome Arrays
Adenosin triphosphate (ATP)-dependent nucleosome remodeling factors sculpt the nucleosomal landscape of eukaryotic chromatin. They deposit, evict, or reposition nucleosomes along DNA in a process termed nucleosome sliding. Remodeling has traditionally been analyzed using mononucleosomes as a model substrate.Petra, Vizjak +2 more
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2009
The basic repeating unit of chromatin, the nucleosome, is known to play a critical role in regulating the process of gene transcription. The positioning of nucleosomes on a promoter is a significant determinant in its responsiveness to gene-inducing signals.
Nicolas, Gévry +3 more
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The basic repeating unit of chromatin, the nucleosome, is known to play a critical role in regulating the process of gene transcription. The positioning of nucleosomes on a promoter is a significant determinant in its responsiveness to gene-inducing signals.
Nicolas, Gévry +3 more
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Nucleosomes as Topological Rheostats
Journal of Biomolecular Structure and Dynamics, 1997Induction of transcription in eukaryotic promoters is accompanied by removal or remodeling of nucleosomes. Given that this process causes release of torsional stress, the question is asked relative to its fate and to its effects on local DNA conformation.
NEGRI, RODOLFO, DI MAURO, Ernesto
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Structural mechanism of cGAS inhibition by the nucleosome
Nature, 2020G. Pathare +13 more
semanticscholar +1 more source
Crystal structure of the nucleosome core particle at 2.8 Å resolution
Nature, 1997K. Luger +4 more
semanticscholar +1 more source