Results 81 to 90 of about 29,622 (225)

Nanomedicine Targeting Macrophage Immunometabolism in Atherosclerosis: Mechanisms and Therapeutic Prospects

open access: yesOrgan Medicine, Volume 3, Issue 1, Page 27-53, March 2026.
ABSTRACT Atherosclerosis, a chronic inflammatory–metabolic disorder, remains a leading cause of cardiovascular morbidity worldwide. This review explores the emerging paradigm of nanomedicine‐based targeting of macrophage immunometabolic reprogramming as a potentially transformative strategy for atherosclerosis treatment.
Zhenyu Liu, Wenfan Yang, Na Wang, Ya Wu
wiley   +1 more source

INFLUENCE OF ANTHELMINTIC DRUGS ON ACTIVITIES OF 5'-NUCLEOTIDASE Bothriocephalus scorpii (Cestoda: Bothriocephalidae)

open access: yesРоссийский паразитологический журнал, 2016
Activities and properties of 5'-nucleotidase in the subcellular fractions of Bothriocephalus scorpii are studied with the use of adenosine monophosphate, inosine monophosphate and cytidine monophosphate as substrates. The high activity of 5'-nucleotidase
E. A. BURENINA
doaj  

Feed-Forward Inhibition of CD73 and Upregulation of Adenosine Deaminase Contribute to the Loss of Adenosine Neuromodulation in Postinflammatory Ileitis

open access: yesMediators of Inflammation, 2014
Purinergic signalling is remarkably plastic during gastrointestinal inflammation. Thus, selective drugs targeting the “purinome” may be helpful for inflammatory gastrointestinal diseases. The myenteric neuromuscular transmission of healthy individuals is
Cátia Vieira   +7 more
doaj   +1 more source

PtrA is required for coordinate regulation of gene expression during phosphate stress in a marine Synechococcus [PDF]

open access: yes, 2010
Previous microarray analyses have shown a key role for the two-component system PhoBR (SYNW0947, SYNW0948) in the regulation of P transport and metabolism in the marine cyanobacterium Synechococcus sp. WH8102. However, there is some evidence that another
Johnson, Daniel   +7 more
core   +1 more source

Physiologically Based Pharmacokinetic Virtual Twin Approach for Fludarabine Dosing in Pediatric Hematopoietic Stem Cell Transplantation

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 3, March 2026.
ABSTRACT Fludarabine (Flu), administered as a prodrug Flu monophosphate, is a lymphodepleting agent used prior to hematopoietic stem cell transplantation (HSCT) which exhibits substantial pharmacokinetics (PK) variability, contributing to suboptimal outcomes.
Mourad Mseddi   +9 more
wiley   +1 more source

Viral Hepatitis And Enzyme Study [PDF]

open access: yes, 2011
The present study was undertaken in sixty patients of viral hepatitis of both sexes ranging 20 to 60 yrs. of age to compare serum levels or 5’Nucleotidase, Alkaline phosphatase, aspartate aminotransferase, and alanine aminotransferase & serum bilirubin ...
Anil Batta, Int J Cur Bio Med Sci.
core  

CD73 (ecto‐5′‐nucleotidase) hepatocyte levels differ across mouse strains and contribute to mallory‐denk body formation [PDF]

open access: yes, 2013
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/100334/1/hep26525 ...
Burant, Charles F.   +9 more
core   +1 more source

Efficacy of Citrus reticulata and Mirazid in treatment of Schistosoma mansoni

open access: yesMemorias do Instituto Oswaldo Cruz, 2005
This work has been carried out to investigate the effect of Schistosoma mansoni infection on mice livers after treatment with the ethanolic extract of Citrus reticulata root or the oleo-resin extract from Myrrh of Commiphora molmol tree (Mirazid), as a ...
Manal A Hamed, Mona H Hetta
doaj   +1 more source

Visceral leishmaniasis patients display altered composition and maturity of neutrophils as well as impaired neutrophil effector functions [PDF]

open access: yes, 2016
Immunologically, active visceral leishmaniasis (VL) is characterised by profound immunosuppression, severe systemic inflammatory responses and an impaired capacity to control parasite replication.
Adem, E   +19 more
core   +3 more sources

High expression of ecto-nucleotidases CD39 and CD73 in human endometrial tumors [PDF]

open access: yes, 2015
One of the strategies used by tumors to evade immunosurveillance is the accumulation of extracellular adenosine, which has immunosupressive and tumor promoting effects.
Aliagas Marín, Elisabeth   +5 more
core   +1 more source

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