Results 21 to 30 of about 2,769,148 (383)

A nuclear orthologue of the dNTP triphosphohydrolase SAMHD1 controls dNTP homeostasis and genomic stability in Trypanosoma brucei

open access: yesFrontiers in Cellular and Infection Microbiology, 2023
Maintenance of dNTPs pools in Trypanosoma brucei is dependent on both biosynthetic and degradation pathways that together ensure correct cellular homeostasis throughout the cell cycle which is essential for the preservation of genomic stability. Both the
Pablo Antequera-Parrilla   +4 more
doaj   +1 more source

Periodic correlation structures in bacterial and archaeal complete genomes [PDF]

open access: yes, 2013
The periodic transference of nucleotide strings in bacterial and archaeal complete genomes is investigated by using the metric representation and the recurrence plot method.
Wu, Zuo-Bing
core   +1 more source

Crystallographic observation of nonenzymatic RNA primer extension

open access: yeseLife, 2018
The importance of genome replication has inspired detailed crystallographic studies of enzymatic DNA/RNA polymerization. In contrast, the mechanism of nonenzymatic polymerization is less well understood, despite its critical role in the origin of life ...
Wen Zhang   +3 more
doaj   +1 more source

Nucleotides Entrapped in Liposome Nanovesicles as Tools for Therapeutic and Diagnostic Use in Biomedical Applications

open access: yesPharmaceutics, 2023
The use of nucleotides for biomedical applications is an old desire in the scientific community. As we will present here, there are references published over the past 40 years with this intended use.
Camila Magalhães Cardador   +7 more
doaj   +1 more source

Determination of total potentially available nucleosides in bovine milk [PDF]

open access: yes, 2010
Bovine colostrum and milk samples were collected from two herds over the course of the first month post-partum, pooled for each herd by stage of lactation and total potentially available nucleosides were determined.
Gill, Brendon D.   +2 more
core   +2 more sources

Viral Protein 1 (VP1) Sequence-Based Genetic Diversity of SAT 2 FMDV Circulating in Ethiopia from 1990 to 2015

open access: yesVeterinary Medicine: Research and Reports, 2023
Fanos Woldemariyam,1,2 Jan Paeshuyse1 1Laboratory of Host-Pathogen Interaction, Division of Animal and Human Health Engineering, Department of Biosystems, KU Leuven, Leuven, Belgium; 2Department of Biomedical Sciences, College of Veterinary Medicine ...
Woldemariyam F, Paeshuyse J
doaj  

Evolutionary degeneration of septins into pseudoGTPases: impacts on a hetero-oligomeric assembly interface

open access: yesFrontiers in Cell and Developmental Biology, 2023
The septin family of eukaryotic proteins comprises distinct classes of sequence-related monomers that associate in a defined order into linear hetero-oligomers, which are capable of polymerizing into cytoskeletal filaments. Like actin and ⍺ and β tubulin,
Alya Hussain   +3 more
doaj   +1 more source

Renalase – a new instrument in multicomponent heart failure assessment

open access: yesKlinicist, 2022
Heart failure (HF) remains a serious problem in Russian and world health care due to the growing morbidity and mortality from complications of heart failure, despite the development and implementation of programs for the early detection and treatment of ...
A. M. Alieva   +5 more
doaj   +1 more source

Targeting nucleotide metabolism: a promising approach to enhance cancer immunotherapy

open access: yesJournal of Hematology & Oncology, 2022
Targeting nucleotide metabolism can not only inhibit tumor initiation and progression but also exert serious side effects. With in-depth studies of nucleotide metabolism, our understanding of nucleotide metabolism in tumors has revealed their non ...
Huai-liang Wu   +5 more
semanticscholar   +1 more source

Tidying up international nucleotide sequence databases [PDF]

open access: yes, 2011
Sequence analysis of the ribosomal RNA operon, particularly the internal transcribed spacer (ITS) region, provides a powerful tool for identification of mycorrhizal fungi.
Abarenkov, Kessy   +12 more
core   +1 more source

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