Results 21 to 30 of about 1,387,306 (292)

Comparative analysis of taste compounds in shiitake mushrooms processed by hot-air drying and freeze drying

open access: yesInternational Journal of Food Properties, 2019
Shiitake mushrooms were processed by hot-air drying (HD) and freeze-drying (FD) to investigate the taste compounds. The total free amino acids in HD samples treated at 60°C was the highest as compared to the other three dried samples.
Xiao Yang   +5 more
doaj   +1 more source

Exploring the nucleotide molecular mechanism of compound kushen injection for lung adenocarcinoma based on network pharmacology and molecular docking

open access: yesFrontiers in Oncology, 2022
Compound kushen injection is an effective traditional Chinese medicine for the treatment of lung cancer. However, its influence on the survival and prognosis of patients with lung adenocarcinoma patients was less studied; especially its pharmacological ...
Zhangpeng Ye   +9 more
doaj   +1 more source

The Interactions of Anti-HIV Pronucleotides with a Model Phospholipid Membrane

open access: yesMolecules
Pronucleotides, after entering the cell, undergo chemical or enzymatic conversion into nucleotides with a free phosphate residue, and the released nucleoside 5′-monophosphate is then phosphorylated to the biologically active form, namely nucleoside 5 ...
Monika Rojewska   +4 more
doaj   +1 more source

Profile of Nucleotides and Nucleosides in Taiwanese Human Milk

open access: yesPediatrics and Neonatology, 2011
Human milk–borne nucleotides and their related metabolic products have been reported to have important physiological roles in breast-fed infants. The purpose of this study was to measure the concentrations of free nucleotides and nucleosides in human ...
Kuo-Yu Liao   +5 more
doaj   +1 more source

Vitamin E Phosphate Nucleoside Prodrugs: A Platform for Intracellular Delivery of Monophosphorylated Nucleosides

open access: yesPharmaceuticals, 2018
Vitamin E phosphate (VEP) nucleoside prodrugs are designed to bypass two mechanisms of tumor resistance to therapeutic nucleosides: nucleoside transport and kinase downregulation.
Richard Daifuku   +2 more
doaj   +1 more source

SHMT2 is essential for mammalian preimplantation embryonic development through de novo biosynthesis of nucleotide metabolites

open access: yesMolecular Therapy: Nucleic Acids
Assisted reproductive technology (ART) is used widely and efficiently to treat infertility. During the ART procedure, one of the main factors affecting the success rate is abnormal development of preimplantation embryos. The establishment and maintenance
Mingze Shi   +10 more
doaj   +1 more source

Inclusion of yeast-derived protein in weanling diet improves growth performance, intestinal health, and anti-oxidative capability of piglets

open access: yesCzech Journal of Animal Science, 2014
The effects of yeast-derived protein (YP) on growth performance, intestinal health, and oxidative status of weanling piglets were investigated. A total of 80 weaned piglets (PIC 327 × 1050, 26 ± 2 days old, 6.20 ± 0.10 kg) were randomly allocated into 2 ...
L. Hu   +12 more
doaj   +1 more source

Sensory taste properties of chicken (Hy-Line brown) soup as prepared with five different parts of the chicken

open access: yesInternational Journal of Food Properties, 2020
Taste is one of the main chicken soup characteristic quality factors as it affects palatability as well as consumer acceptability. Metabolomics coupled with sensory analysis method were applied to explore the differences of taste-chemical compositions in
Lili Zhang   +7 more
doaj   +1 more source

Effective and repeatable chromatographic separation of 5 nucleotides in infant formula milk powder by ion-pair high-performance liquid chromatography–ultraviolet

open access: yesJournal of Dairy Science, 2022
: A robust method using HPLC-UV was developed to improve the accuracy and repeatability of a quantitative method to detect 5 nucleotides (cytidine-monophosphate, uridine monophosphate, adenosine monophosphate, guanine monophosphate, and inosine ...
Yuanjia Chen   +4 more
doaj   +1 more source

Morpholino–RNA duplex exhibits robust, sustained, and safe steric-block antisense activity by intracerebroventricular and intrathecal injection

open access: yesNature Communications
Intrathecal injection of steric-block antisense oligonucleotides (ASOs) provides therapeutic opportunities for targeting the central nervous system (CNS).
Mitsugu Yanagidaira   +6 more
doaj   +1 more source

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