Results 21 to 30 of about 2,732,121 (340)

Crystallographic observation of nonenzymatic RNA primer extension

open access: yeseLife, 2018
The importance of genome replication has inspired detailed crystallographic studies of enzymatic DNA/RNA polymerization. In contrast, the mechanism of nonenzymatic polymerization is less well understood, despite its critical role in the origin of life ...
Wen Zhang   +3 more
doaj   +1 more source

Nucleotides Entrapped in Liposome Nanovesicles as Tools for Therapeutic and Diagnostic Use in Biomedical Applications

open access: yesPharmaceutics, 2023
The use of nucleotides for biomedical applications is an old desire in the scientific community. As we will present here, there are references published over the past 40 years with this intended use.
Camila Magalhães Cardador   +7 more
doaj   +1 more source

Tidying up international nucleotide sequence databases [PDF]

open access: yes, 2011
Sequence analysis of the ribosomal RNA operon, particularly the internal transcribed spacer (ITS) region, provides a powerful tool for identification of mycorrhizal fungi.
Abarenkov, Kessy   +12 more
core   +1 more source

ATR inhibition facilitates targeting of leukemia dependence on convergent nucleotide biosynthetic pathways. [PDF]

open access: yes, 2017
Leukemia cells rely on two nucleotide biosynthetic pathways, de novo and salvage, to produce dNTPs for DNA replication. Here, using metabolomic, proteomic, and phosphoproteomic approaches, we show that inhibition of the replication stress sensing kinase ...
Abt, Evan R   +20 more
core   +2 more sources

Gastroprotective effects of oral nucleotide administration [PDF]

open access: yes, 2006
BACKGROUND AND AIMS: Nucleotides form the building blocks of DNA and are marketed as dietary supplements, alone or in combination with other ingredients, to promote general health.
Belo, A   +4 more
core   +2 more sources

Viral Protein 1 (VP1) Sequence-Based Genetic Diversity of SAT 2 FMDV Circulating in Ethiopia from 1990 to 2015

open access: yesVeterinary Medicine: Research and Reports, 2023
Fanos Woldemariyam,1,2 Jan Paeshuyse1 1Laboratory of Host-Pathogen Interaction, Division of Animal and Human Health Engineering, Department of Biosystems, KU Leuven, Leuven, Belgium; 2Department of Biomedical Sciences, College of Veterinary Medicine ...
Woldemariyam F, Paeshuyse J
doaj  

Evolutionary degeneration of septins into pseudoGTPases: impacts on a hetero-oligomeric assembly interface

open access: yesFrontiers in Cell and Developmental Biology, 2023
The septin family of eukaryotic proteins comprises distinct classes of sequence-related monomers that associate in a defined order into linear hetero-oligomers, which are capable of polymerizing into cytoskeletal filaments. Like actin and ⍺ and β tubulin,
Alya Hussain   +3 more
doaj   +1 more source

Genetic variability of Taenia saginata inferred from mitochondrial DNA sequences [PDF]

open access: yes, 2015
Taenia saginata is an important tapeworm, infecting humans in many parts of the world. The present study was undertaken to identify inter- and intraspecific variation of T.
Babaei, Z.   +5 more
core   +1 more source

Renalase – a new instrument in multicomponent heart failure assessment

open access: yesKlinicist, 2022
Heart failure (HF) remains a serious problem in Russian and world health care due to the growing morbidity and mortality from complications of heart failure, despite the development and implementation of programs for the early detection and treatment of ...
A. M. Alieva   +5 more
doaj   +1 more source

Determination of total potentially available nucleosides in bovine milk [PDF]

open access: yes, 2010
Bovine colostrum and milk samples were collected from two herds over the course of the first month post-partum, pooled for each herd by stage of lactation and total potentially available nucleosides were determined.
Gill, Brendon D.   +2 more
core   +2 more sources

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