Results 111 to 120 of about 280,333 (306)

Regional differences in recombination hotspots between two chicken populations [PDF]

, 2010
Background Although several genetic linkage maps of the chicken genome have been published, the resolution of these maps is limited and does not allow the precise identification of recombination hotspots. The availability of more than 3.2 million SNPs in
Veenendaal, A., Elferink Martin G, van As, P., van As Pieter, Crooijmans, R.P.M.A., Elferink, M.G., Groenen, M.A.M., Groenen Martien AM, Crooijmans Richard PMA, Veenendaal Tineke, As, P., van   +10 more
core   +1 more source

Identification of Single Nucleotide Polymorphisms and analysis of Linkage Disequilibrium in sunflower elite inbred lines using the candidate gene approach

BMC Plant Biology, 2008
Background Association analysis is a powerful tool to identify gene loci that may contribute to phenotypic variation. This includes the estimation of nucleotide diversity, the assessment of linkage disequilibrium structure (LD) and the evaluation of ...
Heinz Ruth A, Hopp H Esteban, Lia Verónica V, Fusari Corina M, Paniego Norma B   +4 more
doaj   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

Analysis of whole genome sequence of strain "0" of avian infectious laryngotracheitis virus

Ветеринария сегодня, 2018
Data on identification and analysis of whole genome nucleotide sequence of strain «O» of avian infectious laryngotracheitis virus are demonstrated.
A. A. Kozlov, N. G. Zinyakov, S. N. Kolosov, N. S. Mudrak, I. A. Chvala   +4 more
doaj  

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source

A genetic variation map for chicken with 2.8 million single-nucleotide polymorphisms

, 2004
We describe a genetic variation map for the chicken genome containing 2.8 million single-nucleotide polymorphisms (SNPs). This map is based on a comparison of the sequences of three domestic chicken breeds (a broiler, a layer and a Chinese silkie) with ...
Wilson, Richard K, Wei, D, Lan, F, Rothwell, L, Zheng, Weimou, Webber, Caleb, Boardman, Paul E., Ponting, Chris, Yang, Xu, Huang, Xiangang, Wei, Dong Qing, Wei, N, Zheng, Hongkun, Bovenhuis, Henk, Wang, J., Brandström, M, Warren, Wesley, Lin, Wei, Liu, Bin, Chen, Chen, Zhang, Zhenpeng, Zhao, W, Huang, Yanqing, Sun, Yongqiao, Zhao, Y, Hu, SN, Ni, PX, Ni, Peixiang, Hao, Bailin, Gordon, Laurie, Wilson, Richard K., Crooijmans, Richard P. M. A., Xie, Fei, Lan, FD, de Koning, Dirk-Jan, Young, John R, Crooijmans, R.P.M.A., Burt, DW, Cheng, Hans H., Wang, XL, Wahlberg, P, Li, Guoqing, Li, Guangyun, Kindlund, E, Aerts, Andrea, Hao, BL, Lamont, Susan J., Zhou, Jun, H, Li, Ruiqiang, Qi, Qiuhui, van der Poel, Jan, Wang, J, Zeng, CQ, Wang, M, Wang, P, Zhao, Wenming, Li, RQ, Glavina, Tijana, Groenen, Martien, Lamont, Susan, Wang, X, Wang, JJ, Zhou, Yan, Li, Ning, Kindlund, Ellen, Wang, Jian, Overton, IM, Dai, Mmingtao, Morrice, Dvaid, Zhang, Yunze, Rogers, S, Young, John, Li, SG, Hunt, H, Wei, Dong, Zhang, Y, Zhang, X, Zhang, Z, Tong, Wei, Groenen, Martien A M, Yang, Zheng, Wong, Gane Ka-Shu, Wang, Xiaoling, Yu, Yingpu, Liu, B, Burt, David W., Wang, Pei, Tong, W, Li, ST, Zhang, J, Qi, Q, Cheng, HH, Hocking, Paul M, de Koning, DJ, Meng, QS, Land, Fengdi, Li, Songgang, Tang, Haizhou, Wang, MH, Cheng, Hans, He, XM, Ovcharenko, I, Crooijmans, Richard, Morrice, David, van der Poel, Jan J, Walker, Brian, Ye, Chen, Ellegren, Hans, Tammi, Martti T., Yu, Jun, Aerts, A, Kaiser, P, Yu, YP, Wang, Xioaling, Li, Heng, Zhang, Xiaowei, Wilson, SA, Bartly, Neil, Wilson, Stuart A., Shi, Jianping, Dong, Le, Lucas, Susan, He, Ximiao, Hillier, LaDeana, Webber, C, Young, JR, ?, ?, Bartley, Neil, Warren, WC, van der Poel, JJ, Wilson, RK, Walker, Brian A., Li, N, Ovcharenko, Ivan, Li, J, Li, H, Yang, SP, Li, G, Overton, Ian M., Li, D, Zhang, Zengjin, Ran, Longhua, Hillier, LaDeana W., Lamont, SJ, Bartley, N, Qi, QH, Walker, BA, Lucas, S, Stubbs, Lisa, Huang, X, Huang, Y, Burt, David, Andersson, Leif, Wang, Jun, Overton, Ian M; id_orcid, Li, Jun, Crooijmans, Richard P M A, Huang, Xingang, Li, Y, Andersson, Björn, Lin, W, Li, W, Wong, GKS, Brandström, Mikael, Li, S, Young, John R., Li, R, Bovenhuis, H., He, X, van der Poel, J.J., Zhang, XW, Hocking, PM, Ran, LH, Gordon, L, Rogers, Sally L, Tammi, Martti, Zeng, C, Dai, MT, Li, GY, Bumstead, N, He, DD, Liu, B., Bovenhuis, H, Yang, N, Wilson, Stuart, Yang, H, Burt, David W, Yang, Huanming, Stubbs, L, Hubbard, Simon, Hillier, LW, Groenen, M.A.M., Wahlberg, Per, Yang, Z, Kaiser, Pete, Xi, Yan, Hu, Songnian, Yang, X, Zhao, WM, Walker, Brian A, van Hateren, A, Zhang, Jianguo, He, D, Lamont, Susan J, Hocking, Paul, Li, YZ, Hu, S, Zhang, Yong, Rothwell, Lisa, Huang, YQ, Li, Wenjie, Wong, GK, Zhang, JG, Zhang, ZJ, Zhang, ZP, Zhang, Jingjing, Li, Shengting, Wong, G.K., Rogers, Sally, Wang, Jianjun, Hunt, Henry, Cheng, Hans H, Zhang, YZ, Li, Guangyuan, Ponting, CP, Gunnarsson, U, Hubbard, Simon J, Zhao, Yiqiang, Tammi, Martti T, Glavina, T, Wong, Gane, Ruan, J, Hubbard, SJ, Yang, Shiaw-Pyng, Boardman, Paul E, Xie, F, Hao, B, Yang, Shuaw-Pyng, Overton, Ian, Boardman, Paul, Yu, J, Wilson, Richard, Law, Andy, Hillier, Ladeana W, Zhang, Zhi-Yong, Zhou, Y, Bumstead, Nat, Ran, L, Hocking, Paul M., Zheng, HK, Zhou, J, Meng, Q, Zhou, H, Lan, Fengdi, Ye, Jia, Tammi, MT, van Hateren, Andy, Kaufman, J, Ponting, Chris P., Dai, Mingtao, He, Dandan, Li, Dawei, Li, DW, Huang, XG, Consortium, International Chicken Polymorphism Map, Chen, Jie, Wang, Miaoheng, Warren, Wesley C, Kaufman, Jim, Yu, Y, Law, A, Ye, C, Shi, JP, Morrice, D, Zhang, JJ, Warren, Wesley C., Xi, Y, Groenen, Martien A. M., Ye, J, Yang, Ning, Wei, Ning, Ellegren, H, Tang, H, Wilson, Stuart A, Ponting, Chris; id_orcid, Andersson, B, Zheng, WM, Zheng, H, Shi, J, Groenen, MA, Gunnarsson, Ulrika, Zeng, Changqing, Chen, J, Ruan, Jue, Li, Yuanzhe, Boardman, PE, Sun, YQ, Ponting, Chris P, Ni, P, Chen, C, Zheng, W, Andersson, L, Poel, J.J., van der, Dong, Wei, Crooijmans, RP, Zhao, YQ, van der Poel, Jan J., Hubbard, Simon; id_orcid, Overton, Ian M, Zhou, Huaijun, Li, WJ, Wang, Jing, Dong, W, Hubbard, Simon J., Meng, Qingshun, Li, GQ, Dong, L, Sun, Y, Dai, M   +319 more
core   +1 more source

High capacity DNA data storage with variable-length Oligonucleotides using repeat accumulate code and hybrid mapping

Journal of Biological Engineering, 2019
Background With the inherent high density and durable preservation, DNA has been recently recognized as a distinguished medium to store enormous data over millennia.
Yixin Wang, Md Noor-A-Rahim, Jingyun Zhang, Erry Gunawan, Yong Liang Guan, Chueh Loo Poh   +5 more
doaj   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

The Ncm-1 gene for resistance to Cucumber mosaic virus in yellow lupin (Lupinus luteus): molecular studies and marker development

, 2012
Cucumber mosaic virus (CMV) is an important virus pathogen of lupins in Australia which causes serious yield losses of up to 60% in epidemic years. In commercially grown lupin (Lupinus angustifolius and L.
Li, Dora
core  

The sim gene of Escherichia coli phage P1: nucleotide sequence and purification of the processed protein

, 1990
Maillou J, Dreiseikelmann B. The sim gene of Escherichia coli phage P1: nucleotide sequence and purification of the processed protein. Virology. 1990;175(2):500-507.The sim gene of bacteriophage P1 causes exclusion of a superinfecting P1 phage.
Maillou, Julia, Dreiseikelmann, Brigitte
core   +1 more source