Results 11 to 20 of about 262,017 (266)
Nucleotide Analog Interference Mapping
Methods, 1999 Single-atom substitution experiments provide atomic resolution biochemical information concerning RNA structure and function. Traditionally, these experiments are performed using chimeric RNAs generated by reassembly of full-length RNA from a synthetic substituted oligonucleotide and a truncated RNA transcript.
S P, Ryder, S A, Strobel
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Mapping of psoralen cross-linked nucleotides in RNA [PDF]
Nucleic Acids Research, 1984 A method is described for using the cross-linking reagent 4'-(hydroxy-methyl)-4,5',8-trimethylpsoralen (HMT) to map base paired regions and higher-order structure within RNA molecules. Applying this method to yeast tRNAPhe, we have specifically identified cross-links within the acceptor stem between U6 X U68, in the D-stem between C11 X C25, and in the
E, Garrett-Wheeler +2 more
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Mapping of Complex Traits by Single-Nucleotide Polymorphisms [PDF]
The American Journal of Human Genetics, 1998 Molecular geneticists are developing the third-generation human genome map with single-nucleotide polymorphisms (SNPs), which can be assayed via chip-based microarrays. One use of these SNP markers is the ability to locate loci that may be responsible for complex traits, via linkage/linkage-disequilibrium analysis.
Zhao, Lue Ping +3 more
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Identification of potential small molecule binding pockets on Rho family GTPases. [PDF]
PLoS ONE, 2012 Rho GTPases are conformational switches that control a wide variety of signaling pathways critical for eukaryotic cell development and proliferation. They represent attractive targets for drug design as their aberrant function and deregulated activity is
Juan Manuel Ortiz-Sanchez +5 more
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Mapping complex traits with single nucleotide polymorphisms [PDF]
Nature Genetics, 1999 Molecular geneticists are developing the third generation human genome map with single nucleotide polymorphisms (SNPs), which can be assayed through chip-based microarrays. One use of these SNP markers is to locate loci that may be responsible for complex traits through linkage/linkage-disequilibrium analysis.
Lue Ping Zhao +3 more
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Single Nucleotide Polymorphism Identification, Characterization, and Linkage Mapping in Quinoa
The Plant Genome, 2012 Quinoa ( Willd.) is an important seed crop throughout the Andean region of South America. It is important as a regional food security crop for millions of impoverished rural inhabitants of the Andean Altiplano (high plains).
P. J. Maughan +8 more
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Genome-wide mapping of DNA strand breaks. [PDF]
PLoS ONE, 2011 Determination of cellular DNA damage has so far been limited to global assessment of genome integrity whereas nucleotide-level mapping has been restricted to specific loci by the use of specific primers.
Frédéric Leduc +6 more
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Nucleotide ‘maps’ of digests of deoxyribonucleic acid [PDF]
Biochemical Journal, 1970 Various digests of 32P-labelled DNA were examined by two-dimensional ionophoresis on cellulose acetate and DEAE-cellulose paper. The products from digestion with pancreatic deoxyribonuclease and Neurospora crassa endonuclease were qualitatively closely similar, but very complex, and were used to investigate the mapping behaviour of nucleotides in ...
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LORSEN: Fast and Efficient eQTL Mapping With Low Rank Penalized Regression
Frontiers in Genetics, 2021 Characterization of genetic variations that are associated with gene expression levels is essential to understand cellular mechanisms that underline human complex traits.
Cheng Gao, Hairong Wei, Kui Zhang
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BMC Plant Biology, 2007 Background Association analysis is an alternative way for QTL mapping in ryegrass. So far, knowledge on nucleotide diversity and linkage disequilibrium in ryegrass is lacking, which is essential for the efficiency of association analyses.
Asp Torben +4 more
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