Results 21 to 30 of about 458,823 (303)
Genome-wide mapping of DNA strand breaks. [PDF]
Determination of cellular DNA damage has so far been limited to global assessment of genome integrity whereas nucleotide-level mapping has been restricted to specific loci by the use of specific primers.
Frédéric Leduc +6 more
doaj +1 more source
Gi- and Gs-coupled GPCRs show different modes of G-protein binding. [PDF]
More than two decades ago, the activation mechanism for the membrane-bound photoreceptor and prototypical G protein-coupled receptor (GPCR) rhodopsin was uncovered.
Altenbach, Christian +7 more
core +1 more source
Nucleotide ‘maps’ of digests of deoxyribonucleic acid [PDF]
Various digests of 32P-labelled DNA were examined by two-dimensional ionophoresis on cellulose acetate and DEAE-cellulose paper. The products from digestion with pancreatic deoxyribonuclease and Neurospora crassa endonuclease were qualitatively closely similar, but very complex, and were used to investigate the mapping behaviour of nucleotides in ...
openaire +2 more sources
LORSEN: Fast and Efficient eQTL Mapping With Low Rank Penalized Regression
Characterization of genetic variations that are associated with gene expression levels is essential to understand cellular mechanisms that underline human complex traits.
Cheng Gao, Hairong Wei, Kui Zhang
doaj +1 more source
Single nucleotide polymorphisms from Theobroma cacao expressed sequence tags associated with witches' broom disease in cacao [PDF]
In order to increase the efficiency of cacao tree resistance to witches¿ broom disease, which is caused by Moniliophthora perniciosa (Tricholomataceae), we looked for molecular markers that could help in the selection of resistant cacao genotypes.
Carels, Nicolas +10 more
core +1 more source
Background Association analysis is an alternative way for QTL mapping in ryegrass. So far, knowledge on nucleotide diversity and linkage disequilibrium in ryegrass is lacking, which is essential for the efficiency of association analyses.
Asp Torben +4 more
doaj +1 more source
Simple sequence repeats of DNA (SSRs) are the most popular source of genetic markers used in population genetics, phylogenetics, and genetic mapping. A large number of nucleotide repeats enriched in G and C were identified. 336 mononucleotide motifs with
Boiko S.M.
doaj +1 more source
Nucleotide sequence-directed mapping of the nucleosomes
The concept of sequence-dependent deformational anisotropy of DNA proposed earlier is further elaborated and a computational procedure is developed for the sequence-directed mapping of the nucleosomes along chromatin DNA nucleotide sequences. The deformational anisotropy is found to be nonuniform along the molecule of the nucleosomal DNA, suggesting ...
G, Mengeritsky, E N, Trifonov
openaire +3 more sources
Synteny analysis in Rosids with a walnut physical map reveals slow genome evolution in long-lived woody perennials. [PDF]
BackgroundMutations often accompany DNA replication. Since there may be fewer cell cycles per year in the germlines of long-lived than short-lived angiosperms, the genomes of long-lived angiosperms may be diverging more slowly than those of short-lived ...
Aradhya, Mallikarjuna +9 more
core +2 more sources
Transcriptome-wide mapping reveals a diverse dihydrouridine landscape including mRNA
Dihydrouridine is a modified nucleotide universally present in tRNAs, but the complete dihydrouridine landscape is unknown in any organism. We introduce dihydrouridine sequencing (D-seq) for transcriptome-wide mapping of D with single-nucleotide ...
Austin S. Draycott +7 more
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