Results 21 to 30 of about 280,333 (306)

Nucleotide sequence-directed mapping of the nucleosomes

open access: yesNucleic Acids Research, 1983
The concept of sequence-dependent deformational anisotropy of DNA proposed earlier is further elaborated and a computational procedure is developed for the sequence-directed mapping of the nucleosomes along chromatin DNA nucleotide sequences. The deformational anisotropy is found to be nonuniform along the molecule of the nucleosomal DNA, suggesting ...
G, Mengeritsky, E N, Trifonov
openaire   +3 more sources

Identification of potential small molecule binding pockets on Rho family GTPases. [PDF]

open access: yesPLoS ONE, 2012
Rho GTPases are conformational switches that control a wide variety of signaling pathways critical for eukaryotic cell development and proliferation. They represent attractive targets for drug design as their aberrant function and deregulated activity is
Juan Manuel Ortiz-Sanchez   +5 more
doaj   +1 more source

Preliminary Identification of Key Genes Controlling Peach Pollen Fertility Using Genome-Wide Association Study

open access: yesPlants, 2021
Previous genetic mapping helped detect a ~7.52 Mb putative genomic region for the pollen fertility trait on peach Chromosome 06 (Chr.06), which was too long for candidate gene characterization.
Zhenyu Huang   +4 more
doaj   +1 more source

Nucleotide ‘maps’ of digests of deoxyribonucleic acid [PDF]

open access: yesBiochemical Journal, 1970
Various digests of 32P-labelled DNA were examined by two-dimensional ionophoresis on cellulose acetate and DEAE-cellulose paper. The products from digestion with pancreatic deoxyribonuclease and Neurospora crassa endonuclease were qualitatively closely similar, but very complex, and were used to investigate the mapping behaviour of nucleotides in ...
openaire   +2 more sources

Extent of genome-wide linkage disequilibrium in Australian Holstein-Friesian cattle based on a high-density SNP panel [PDF]

open access: yes, 2008
BACKGROUND: The extent of linkage disequilibrium (LD) within a population determines the number of markers that will be required for successful association mapping and marker-assisted selection.
Andrew R Collins   +27 more
core   +1 more source

Comparative BAC-based mapping in the white-throated sparrow, a novel behavioral genomics model, using interspecies overgo hybridization [PDF]

open access: yes, 2011
BACKGROUND The genomics era has produced an arsenal of resources from sequenced organisms allowing researchers to target species that do not have comparable mapping and sequence information.
Tuttle, Elaina M   +11 more
core   +1 more source

Single Nucleotide Polymorphism Identification, Characterization, and Linkage Mapping in Quinoa

open access: yesThe Plant Genome, 2012
Quinoa ( Willd.) is an important seed crop throughout the Andean region of South America. It is important as a regional food security crop for millions of impoverished rural inhabitants of the Andean Altiplano (high plains).
P. J. Maughan   +8 more
doaj   +1 more source

Genome-wide mapping of DNA strand breaks. [PDF]

open access: yesPLoS ONE, 2011
Determination of cellular DNA damage has so far been limited to global assessment of genome integrity whereas nucleotide-level mapping has been restricted to specific loci by the use of specific primers.
Frédéric Leduc   +6 more
doaj   +1 more source

Short communication: Characterization of the genome-wide linkage disequilibrium in 2 divergent selection lines of dairy cows [PDF]

open access: yes, 2010
The objective of this study was to describe results of a genome-wide map of single nucleotide polymorphisms (SNP) and assess the linkage disequilibrium (LD) level in 2 divergent selection lines of dairy cows. DNA extracted from 299 Holstein cows was used
Coffey, M. P., Banos, G.
core   +1 more source

Nucleotide diversity and linkage disequilibrium in 11 expressed resistance candidate genes in Lolium perenne

open access: yesBMC Plant Biology, 2007
Background Association analysis is an alternative way for QTL mapping in ryegrass. So far, knowledge on nucleotide diversity and linkage disequilibrium in ryegrass is lacking, which is essential for the efficiency of association analyses.
Asp Torben   +4 more
doaj   +1 more source

Home - About - Disclaimer - Privacy