Results 11 to 20 of about 1,708,901 (308)

Mapping of psoralen cross-linked nucleotides in RNA [PDF]

Nucleic Acids Research, 1984
A method is described for using the cross-linking reagent 4'-(hydroxy-methyl)-4,5',8-trimethylpsoralen (HMT) to map base paired regions and higher-order structure within RNA molecules. Applying this method to yeast tRNAPhe, we have specifically identified cross-links within the acceptor stem between U6 X U68, in the D-stem between C11 X C25, and in the
E, Garrett-Wheeler, R E, Lockard, A, Kumar   +2 more
openaire   +2 more sources

Mapping of Complex Traits by Single-Nucleotide Polymorphisms [PDF]

The American Journal of Human Genetics, 1998
Molecular geneticists are developing the third-generation human genome map with single-nucleotide polymorphisms (SNPs), which can be assayed via chip-based microarrays. One use of these SNP markers is the ability to locate loci that may be responsible for complex traits, via linkage/linkage-disequilibrium analysis.
Zhao, Lue Ping, Aragaki, Corinne, Hsu, Li, Quiaoit, Filemon   +3 more
openaire   +2 more sources

Nucleotide Analog Interference Mapping

Methods, 1999
Single-atom substitution experiments provide atomic resolution biochemical information concerning RNA structure and function. Traditionally, these experiments are performed using chimeric RNAs generated by reassembly of full-length RNA from a synthetic substituted oligonucleotide and a truncated RNA transcript.
S P, Ryder, S A, Strobel
openaire   +2 more sources

Single nucleotide polymorphisms (SNPs) that map to gaps in the human SNP map [PDF]

Nucleic Acids Research, 2003
An international effort is underway to generate a comprehensive haplotype map (HapMap) of the human genome represented by an estimated 300,000 to 1 million 'tag' single nucleotide polymorphisms (SNPs). Our analysis indicates that the current human SNP map is not sufficiently dense to support the HapMap project.
Circe, Tsui, Laura E, Coleman, Jacqulyn L, Griffith, E Andrew, Bennett, Summer G, Goodson, Jason D, Scott, W Stephen, Pittard, Scott E, Devine   +7 more
openaire   +2 more sources

Billa Kalina [cartographic material] /

, 1948
Topographic map of Billa Kalina, South Australia. Relief shown by spot heights.; On verso: Mis.13079.; Also available in an electronic version via the internet at: http://nla.gov.au/nla.map ...
Australia. National Mapping Section.
core   +3 more sources

Nucleotide ‘maps’ of digests of deoxyribonucleic acid [PDF]

Biochemical Journal, 1970
Various digests of 32P-labelled DNA were examined by two-dimensional ionophoresis on cellulose acetate and DEAE-cellulose paper. The products from digestion with pancreatic deoxyribonuclease and Neurospora crassa endonuclease were qualitatively closely similar, but very complex, and were used to investigate the mapping behaviour of nucleotides in ...
openaire   +2 more sources

Nucleotide sequence-directed mapping of the nucleosomes

Nucleic Acids Research, 1983
The concept of sequence-dependent deformational anisotropy of DNA proposed earlier is further elaborated and a computational procedure is developed for the sequence-directed mapping of the nucleosomes along chromatin DNA nucleotide sequences. The deformational anisotropy is found to be nonuniform along the molecule of the nucleosomal DNA, suggesting ...
G, Mengeritsky, E N, Trifonov
openaire   +3 more sources

Identification of potential small molecule binding pockets on Rho family GTPases. [PDF]

PLoS ONE, 2012
Rho GTPases are conformational switches that control a wide variety of signaling pathways critical for eukaryotic cell development and proliferation. They represent attractive targets for drug design as their aberrant function and deregulated activity is
Juan Manuel Ortiz-Sanchez, Sara E Nichols, Jacqueline Sayyah, Joan Heller Brown, J Andrew McCammon, Barry J Grant   +5 more
doaj   +1 more source

Single Nucleotide Polymorphism Identification, Characterization, and Linkage Mapping in Quinoa

The Plant Genome, 2012
Quinoa ( Willd.) is an important seed crop throughout the Andean region of South America. It is important as a regional food security crop for millions of impoverished rural inhabitants of the Andean Altiplano (high plains).
P. J. Maughan, S. M. Smith, J. A. Rojas-Beltrán, D. Elzinga, J. A. Raney, E. N. Jellen, A. Bonifacio, J. A. Udall, D. J. Fairbanks   +8 more
doaj   +1 more source

Preliminary Identification of Key Genes Controlling Peach Pollen Fertility Using Genome-Wide Association Study

Plants, 2021
Previous genetic mapping helped detect a ~7.52 Mb putative genomic region for the pollen fertility trait on peach Chromosome 06 (Chr.06), which was too long for candidate gene characterization.
Zhenyu Huang, Fei Shen, Yuling Chen, Ke Cao, Lirong Wang   +4 more
doaj   +1 more source