Results 31 to 40 of about 262,017 (266)

Development and characterization of genomic and expressed SSRs in citrus by genome-wide analysis. [PDF]

open access: yesPLoS ONE, 2013
Microsatellites or simple sequence repeats (SSRs) are one of the most popular sources of genetic markers and play a significant role in plant genetics and breeding.
Sheng-Rui Liu   +4 more
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Single-Nucleotide-Polymorphism-Based Association Mapping of Dog Stereotypes [PDF]

open access: yesGenetics, 2008
Abstract Phenotypic stereotypes are traits, often polygenic, that have been stringently selected to conform to specific criteria. In dogs, Canis familiaris, stereotypes result from breed standards set for conformation, performance (behaviors), etc.
Paul, Jones   +5 more
openaire   +2 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Association Mapping for Improvement of Quantitative Traits in Plant Breeding Populations

open access: yesNepal Journal of Biotechnology, 2012
DNA-based molecular markers have been extensively utilized for mapping of genes and quantitative trait loci (QTL) of interest based on linkage analysis in mapping populations.
Umesh R Rosyara, Bal K Joshi
doaj   +1 more source

Population structure and association mapping studies for yield-related traits in Maize (Zea mays L.)

open access: yesCurrent Plant Biology, 2019
Association mapping is an efficient approach for dissecting the genetic architecture of yield-related traits using single nucleotide polymorphism (SNP) markers in maize. The present study was carried out with a set of 93 diverse maize accessions with the
S. Sivakumar   +6 more
doaj   +1 more source

Single nucleotide polymorphisms (SNPs) that map to gaps in the human SNP map [PDF]

open access: yesNucleic Acids Research, 2003
An international effort is underway to generate a comprehensive haplotype map (HapMap) of the human genome represented by an estimated 300,000 to 1 million 'tag' single nucleotide polymorphisms (SNPs). Our analysis indicates that the current human SNP map is not sufficiently dense to support the HapMap project.
Circe, Tsui   +7 more
openaire   +2 more sources

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

High-throughput isolation and mapping of C. elegans mutants susceptible to pathogen infection. [PDF]

open access: yesPLoS ONE, 2008
We present a novel strategy that uses high-throughput methods of isolating and mapping C. elegans mutants susceptible to pathogen infection. We show that C.
Laura E Fuhrman   +2 more
doaj   +1 more source

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