Population structure and association mapping studies for yield-related traits in Maize (Zea mays L.)
Current Plant Biology, 2019 Association mapping is an efficient approach for dissecting the genetic architecture of yield-related traits using single nucleotide polymorphism (SNP) markers in maize. The present study was carried out with a set of 93 diverse maize accessions with the
S. Sivakumar +6 more
doaj +1 more source
Single nucleotide polymorphisms (SNPs) that map to gaps in the human SNP map [PDF]
Nucleic Acids Research, 2003 An international effort is underway to generate a comprehensive haplotype map (HapMap) of the human genome represented by an estimated 300,000 to 1 million 'tag' single nucleotide polymorphisms (SNPs). Our analysis indicates that the current human SNP map is not sufficiently dense to support the HapMap project.
Circe, Tsui +7 more
openaire +2 more sources
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Intramolecular integration within Moloney murine leukemia virus DNA [PDF]
, 1981 By screening a library of unintegrated, circular Moloney murine leukemia virus (M-MuLV) DNA cloned in lambda phage, we found that approximately 20% of the M-MuLV DNA inserts contained internal sequence deletions or inversions.
Baltimore, David +3 more
core
QQ-SNV: single nucleotide variant detection at low frequency by comparing the quality quantiles [PDF]
, 2015 Background: Next generation sequencing enables studying heterogeneous populations of viral infections. When the sequencing is done at high coverage depth ("deep sequencing"), low frequency variants can be detected.
Aerssens, Jeroen +7 more
core +4 more sources
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Mutagenesis of the conserved 51-nucleotide region of Sindbis virus [PDF]
, 1990 We have constructed 25 site-specific mutations in a domain of 51 nucleotides in Sindbis virus that is highly conserved among all alphaviruses sequenced to date.
Niesters, Hubert G. M. +1 more
core
Hyb:A bioinformatics pipeline for the analysis of CLASH (crosslinking, ligation and sequencing of hybrids) data [PDF]
, 2013 Peer reviewedPublisher ...
Aiba +32 more
core +2 more sources
High-throughput isolation and mapping of C. elegans mutants susceptible to pathogen infection. [PDF]
PLoS ONE, 2008 We present a novel strategy that uses high-throughput methods of isolating and mapping C. elegans mutants susceptible to pathogen infection. We show that C.
Laura E Fuhrman +2 more
doaj +1 more source
Genome-wide mapping of nucleotide excision repair with XR-seq [PDF]
Nature Protocols, 2018 Nucleotide excision repair is a versatile mechanism to repair a variety of bulky DNA adducts. We developed excision repair sequencing (XR-seq) to study nucleotide excision repair of DNA adducts in humans, mice, Arabidopsis thaliana, yeast and Escherichia coli. In this protocol, the excised oligomers, generated in the nucleotide excision repair reaction,
Jinchuan Hu +6 more
openaire +4 more sources