Results 51 to 60 of about 280,333 (306)

A genome-wide library of CB4856/N2 introgression lines of Caenorhabditis elegans

, 2009
Recombinant inbred lines (RILs) derived from Caenorhabditis elegans wild-type N2 and CB4856 are increasingly being used for mapping genes underlying complex traits.
Jan Kammenga, Snoek, L.B., L. Basten Snoek, Emilie Fradin, Riksen, J.A.G., Joost Riksen, Doroszuk, A., Kammenga, J.E., Agnieszka Doroszuk, Fradin, E.   +9 more
core   +1 more source

A catalogue of validated single nucleotide polymorphisms in bovine orthologs of mammalian imprinted genes and associations with beef production traits [PDF]

, 2010
peer-reviewedGenetic (or ‘genomic’) imprinting, a feature of approximately 100 mammalian genes, results in monoallelic expression from one of the two parentally inherited chromosomes. To date, most studies have been directed on imprinted genes in murine
Magee, David A, Park, Stephen D. E., B.W. Wickham, Kenny, David A., Wickham, Brian W., K.M. Sikora, R.D. Evans, Sweeney, Torres, C. Spillane, T. Sweeney, D.P. Berry, S.D.E. Park, Berkowicz, Erik W, D.E. MacHugh, Evans, R. D., D.A. Kenny, Spillane, Charles, D.A. Magee, Kelly, Alan K, E.W. Berkowicz, Sikora, Klaudia M, MacHugh, David E, A.K. Kelly, Berry, Donagh   +23 more
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Association Mapping for Improvement of Quantitative Traits in Plant Breeding Populations

Nepal Journal of Biotechnology, 2012
DNA-based molecular markers have been extensively utilized for mapping of genes and quantitative trait loci (QTL) of interest based on linkage analysis in mapping populations.
Umesh R Rosyara, Bal K Joshi
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

QTL mapping in autotetraploids using SNP dosage information [PDF]

, 2014
Dense linkage maps derived by analysing SNP dosage in autotetraploids provide detailed information about the location of, and genetic model at, quantitative trait loci.
Christine A. Hackett, Glenn J. Bryan, Bradshaw, John E., Bryan, Glenn J., John E. Bradshaw, Hackett, Christine A.   +5 more
core   +1 more source

Population structure and association mapping studies for yield-related traits in Maize (Zea mays L.)

Current Plant Biology, 2019
Association mapping is an efficient approach for dissecting the genetic architecture of yield-related traits using single nucleotide polymorphism (SNP) markers in maize. The present study was carried out with a set of 93 diverse maize accessions with the
S. Sivakumar, M. Dhasarathan, A. Karthikeyan, P. Bharathi, N. Kumari vinodhana, K. Ganesamurthy, N. Senthil   +6 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Mapping ribonucleotides embedded in genomic DNA to single-nucleotide resolution using Ribose-Map [PDF]

Nature Protocols, 2020
ABSTRACT Ribose-Map is a user-friendly, standardized bioinformatics toolkit for the comprehensive analysis of ribonucleotide sequencing experiments. It allows researchers to map the locations of ribonucleotides in DNA to single-nucleotide resolution and identify biological signatures of ribonucleotide incorporation.
Alli L. Gombolay, Francesca Storici
openaire   +2 more sources

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source