Results 141 to 150 of about 749,080 (252)

Modulating Signal Generation in Aptamer‐Based CNT‐FET Biosensors by Controlling the Functionalization Route

Advanced Sensor Research, EarlyView.
The impact of different assembly strategies is discussed on the performance of nanoscale aptamer‐based SWCNT‐FET biosensors. By combining electrical and optical characterization, this is revealed that how aptamer conformation affects local electrostatic changes within the Debye length, leading to distinct sensor responses.
Haosen Miao, Gririraj Manoharan, Ahran Lim, Peter Mirau, Jorge L. Chávez, Chang‐Seuk Lee, Matteo Palma   +6 more
wiley   +1 more source

DeepRNA-Twist: language-model-guided RNA torsion angle prediction with attention-inception network. [PDF]

Brief Bioinform
Abir AR, Tahmid MT, Rayan RI, Rahman MS.
europepmc   +1 more source

Opportunities in Therapeutic mRNA Stabilization: Sequence, Structure, Adjuvants and Vectors

Advanced Therapeutics, EarlyView.
Current mRNA lipid nanoparticles rely on cold storage, which increases the cost and reduces access to the vaccines. As mRNA expands to other clinical opportunities, better methods to stabilize the medicines during shipping, storage, and delivery are needed.
Joshua A. Choe, Jacobus Burger, Jamie Jones, Apurva Panjla, William L. Murphy   +4 more
wiley   +1 more source

Supplemental effect of dietary nucleotides on hematological profile, hepatic biomarkers, antioxidant capacity, and digestive functions in Sterlet sturgeon, Acipenser ruthenus. [PDF]

Sci Rep
Taklu M, Islami HR, Shekarabi SPH, Mousavi SA, Jourdehi AY.   +4 more
europepmc   +1 more source

Emerging Therapeutic Strategies for Hearing Loss

Advanced Therapeutics, EarlyView.
Challenges still exist in treating hearing loss in cases of severe damage to hair cells or spiral ganglion neurons. Here, a schematic diagram of cochlear sensory hair cells and auditory nerves is presented. It is found that in normal Corti organs, hair cells have upright stereocilia at the top and auditory neurons at the base. Ototoxic drugs, noise, or
Shanying Han, Tian Shen, Weiwei He, Hao Wei, Xiaolong Zhao, Wen Yang, Chuan Bu, Xinghua Tang, Yu Zhao, Jiangang Fan   +9 more
wiley   +1 more source

Quantitative and Multiplexing Analysis of MicroRNAs by Direct Full-Length Sequencing in Nanopores. [PDF]

J Am Chem Soc
Shi C, Yang D, Ma X, Chen Y, Hou P, Pan L, Li M, Wang P.   +7 more
europepmc   +1 more source

FUS Selectively Facilitates circRNAs Packing into Small Extracellular Vesicles within Hypoxia Neuron

Advanced Science, EarlyView.
This study aimed to unravel the role of FUS in the loading of functional circRNAs into neuronal sEVs under hypoxic conditions, which involves their aggregations in SGs and specific interaction between the FUS Zf_RanBP domain to regulate circRNA sorting in sEVs.
Jiankun Zang, Yousheng Wu, Xuanlin Su, Kaiwei Cai, Man Ke, Niu He, Huili Zhu, Zefeng Tan, Jielin Zhu, Wensheng He, Min Peng, Shiqing Zhang, Hongcheng Mai, Anding Xu, Dan Lu   +14 more
wiley   +1 more source

Dietary supplementation of new-born foals with free nucleotides positively affects neonatal diarrhoea management. [PDF]

Ir Vet J
Penazzi L, Pagliara E, Nervo T, Ala U, Bertuglia A, Romano G, Hattab J, Tiscar PG, Bergagna S, Pagliasso G, Antoniazzi S, Cavallarin L, Valle E, Prola L.   +13 more
europepmc   +1 more source

Lipid Droplet‐Derived Biomimetic Nanocarriers for the Enhancement of Porcine Intermuscular Fat Content

Advanced Science, EarlyView.
The article presents the development of artificial lipid droplets (aLDs) as biomimetic nanocarriers to enhance intramuscular fat (IMF) content in pigs. These aLDs, loaded with oleic acid, significantly increase IMF by up to 35% in muscle tissues without adverse side effects. This innovative approach improves pork quality by enhancing marbling, offering
Pengxiang Zhao, Hongbo Han, Jingjie Hao, Ziwei Yu, Zichen Zhao, Lupeng Chen, Heng Wang, Jian Wu, Zhuqing Ren   +8 more
wiley   +1 more source

Five unaddressed questions about cytokinin biosynthesis. [PDF]

J Exp Bot
Sakakibara H.
europepmc   +1 more source