Electronic signature of DNA nucleotides via transverse transport
We report theoretical studies of charge transport in single-stranded DNA in the direction perpendicular to the backbone axis. We find that, if the electrodes which sandwich the DNA have the appropriate spatial width, each nucleotide carries a unique ...
Di Ventra, Massimiliano, Zwolak, Michael
core +1 more source
Effect of nucleotides on broiler performance and carcass yield
This study aimed at evaluating the effect of nucleotides on the performance and carcass yield of broilers fed diets with no antibiotic growth promoters (AGP), anticoccidials, or animal feedstuffs. In the trial, 600 Ross 308 male broilers were distributed
VC Pelícia +7 more
doaj +1 more source
Simultaneous quantification of 12 different nucleotides and nucleosides released from renal epithelium and in human urine samples using ion-pair reversed-phase HPLC [PDF]
Nucleotides and nucleosides are not only involved in cellular metabolism but also act extracellularly via P1 and P2 receptors, to elicit a wide variety of physiological and pathophysiological responses through paracrine and autocrine signalling pathways.
Alberto Contreras-Sanz +60 more
core +2 more sources
Thermophilic phosphoribosyltransferases Thermus thermophilus HB27 in nucleotide synthesis
Phosphoribosyltransferases are the tools that allow the synthesis of nucleotide analogues using multi-enzymatic cascades. The recombinant adenine phosphoribosyltransferase (TthAPRT) and hypoxanthine phosphoribosyltransferase (TthHPRT) from Thermus ...
Ilja V. Fateev +9 more
doaj +1 more source
Genome-scale high-resolution mapping of activating and repressive nucleotides in regulatory regions
Massively parallel reporter assays (MPRAs) enable nucleotide-resolution dissection of transcriptional regulatory regions, such as enhancers, but only few regions at a time.
J. Ernst +6 more
semanticscholar +1 more source
Atomic mutagenesis of stop codon nucleotides reveals the chemical prerequisites for release factor-mediated peptide release. [PDF]
Termination of protein synthesis is triggered by the recognition of a stop codon at the ribosomal A site and is mediated by class I release factors (RFs).
Clementi, Nina +11 more
core +3 more sources
Macropinocytosis confers resistance to therapies targeting cancer anabolism. [PDF]
Macropinocytic cancer cells scavenge amino acids from extracellular proteins. Here, we show that consuming necrotic cell debris via macropinocytosis (necrocytosis) offers additional anabolic benefits.
Edinger, Aimee L, Jayashankar, Vaishali
core
Error correction and diversity analysis of population mixtures determined by NGS [PDF]
The impetus for this work was the need to analyse nucleotide diversity in a viral mix taken from honeybees. The paper has two findings. First, a method for correction of next generation sequencing error in the distribution of nucleotides at a site is ...
Burroughs, Nigel J. +3 more
core +3 more sources
A new and versatile method for the successful conversion of AFLP-TM markers into simple single locus markers [PDF]
Genetic markers can efficiently be obtained by using amplified fragment length polymorphism (AFLP) fingerprinting because no prior information on DNA sequence is required.
Brugmans, B.W. +4 more
core +2 more sources
A series of 5′-phosphorylated (dialkyl phosphates, diaryl phosphates, phosphoramidates, H-phosphonates, phosphates) 1,2,3-triazolyl nucleoside analogues in which the 1,2,3-triazole-4-yl-β-D-ribofuranose fragment is attached via a methylene group or a ...
Dmitry A. Tatarinov +12 more
doaj +1 more source

