Results 61 to 70 of about 2,090,052 (356)
BackgroundColon adenocarcinoma (COAD) is characterized by high mortality and poor prognosis. Endoplasmic reticulum stress-related gene (ERSG) plays an indispensable role in the progression and immunotherapy of COAD.
Lichao Cao+28 more
doaj +1 more source
Chromatin and Nuclear Dynamics in the Maintenance of Replication Fork Integrity
Replication of the eukaryotic genome is a highly regulated process and stringent control is required to maintain genome integrity. In this review, we will discuss the many aspects of the chromatin and nuclear environment that play key roles in the ...
Jack Wootton, Evi Soutoglou
doaj +1 more source
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
The mitochondrial and nuclear genomes of Eukaryotes are inherited separately and consequently follow distinct evolutionary paths. Nevertheless, the encoding of many mitochondrial proteins by the nuclear genome shows the high level of integration they ...
Pierre-Henri Clergeot, Åke Olson
doaj +1 more source
Subsonic and supersonic nucleus-acoustic solitary waves in thermally degenerate plasmas with heavy nucleus species [PDF]
A fully ionized multi-nucleus plasma system (containing thermally degenerate electron species, non-degenerate warm light nucleus species, and low dense stationary heavy nucleus species) is considered. The basic features of thermal and degenerate pressure driven small and arbitrary amplitude subsonic and supersonic nucleus-acoustic solitary waves in ...
arxiv
Dilepton production from the Color Glass Condensate [PDF]
We consider dilepton production in high energy proton-nucleus (and very forward nucleus-nucleus) collisions. Treating the target nucleus as a Color Glass Condensate and describing the projectile proton (nucleus) as a collection of quarks and gluons as in the parton model, we calculate the differential cross section for dilepton production in quark ...
arxiv +1 more source
Making tau amyloid models in vitro: a crucial and underestimated challenge
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
Nucleus-nucleus collisions at highest energies [PDF]
The microscopic phasespace approach URQMD is used to investigate the stopping power and particle production in heavy systems at SPS and RHIC energies. We find no gap in the baryon rapidity distribution even at RHIC.
Amelin, Nikolai+12 more
core
The production of residual nuclei in peripheral high energy nucleus-nucleus interactions [PDF]
A formation zone intranuclear cascade model is applied to peripheral nucleus-nucleus collisions. We calculate the excitation energies of prefragments, treat their further nuclear disintegration and introduce a model for nuclear deexcitation by photon emission.
arxiv +1 more source
Pion production in nucleus-nucleus collisions [PDF]
Current work on pion production in high‐energy nucleus‐nucleus collisions is reviewed. The majority of existing data are of the inclusive variety in which a single final state pion is detected. Experimental data are compared and their possible contributions to obtaining new information on nuclear structure is discussed.
openaire +3 more sources