Results 61 to 70 of about 1,491,280 (348)
FEBS Letters, EarlyView.The protonated form of butyrate, as well as other short‐chain fatty acids (SCFAs), is membrane permeable. In acidic extracellular environments, this can lead to intracellular accumulation of SCFAs and cytosolic acidification. This phenomenon will be particularly relevant in acidic environments such as the large intestine or tumor microenvironments ...
Muwei Jiang +2 more
wiley +1 more source
A lysosome-to-nucleus signalling mechanism senses and regulates the lysosome via mTOR and TFEB
EMBO Journal, 2012 The lysosome plays a key role in cellular homeostasis by controlling both cellular clearance and energy production to respond to environmental cues. However, the mechanisms mediating lysosomal adaptation are largely unknown.
C. Settembre +12 more
semanticscholar +1 more source
A stepwise emergence of evolution in the RNA world
FEBS Letters, EarlyView.How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley +1 more source
eLife, 2019 Chromosomal DNA elements are organized into spatial domains within the eukaryotic nucleus. Sites undergoing DNA replication, high-level transcription, and repair of double-strand breaks coalesce into foci, although the significance and mechanisms giving ...
Haiyang Zhang +5 more
doaj +1 more source
Lithuanian Syllable: The Hierarchy of Syllable Constituents and Syllable Weight
Respectus Philologicus, 2022 The article aims to establish the hierarchy of Lithuanian syllable constituents and determine how syllables should be interpreted in terms of syllable weight. The empirical data based on 311 000 syllables show that the variety of consonants in the onset
Asta Kazlauskienė
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Pion production in nucleus-nucleus collisions [PDF]
AIP Conference Proceedings, 1975 Current work on pion production in high‐energy nucleus‐nucleus collisions is reviewed. The majority of existing data are of the inclusive variety in which a single final state pion is detected. Experimental data are compared and their possible contributions to obtaining new information on nuclear structure is discussed.
openaire +3 more sources
Heavy flavor in nucleus-nucleus and proton-nucleus: quenching, flow and correlations [PDF]
Nuclear and Particle Physics Proceedings, 2016 4 pages, proceedings of "Hard Probes 2015"
Andrea Beraudo +4 more
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FEBS Letters, EarlyView.The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp +5 more
wiley +1 more source
HADRON-NUCLEUS AND NUCLEUS-NUCLEUS SCATTERING AT HIGH ENERGIES
Le Journal de Physique Colloques, 1972 A review talk on the current study of hadron-nucleus and nucleus-nucleus scattering at the energies above 100 MeV.
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