Results 81 to 90 of about 1,491,280 (348)
Mechanism of Cell Cycle Asynchrony within the Animal Organism [PDF]
International Journal of Biomedicine, 2013 Every organism is composed of multi-cellular systems. Each of these cells, from the time of birth until death, often plays a polyfunctional role. Obviously, this cycle must include periods of intense work and leisure.
Michael T. Lucenko, PhD, ScD
doaj
A Globin in the Nucleus! [PDF]
Journal of Biological Chemistry, 2003 Cytoglobin and neuroglobin are recently discovered members of the globin family. In situ hybridization localized neuroglobin mainly in brain and retina, while cytoglobin was expressed ubiquitously in all analyzed tissues. In the present study, polyclonal antibodies were raised against both proteins and the distribution of them was studied by ...
Geuens, Eva +5 more
openaire +4 more sources
Aβ42 promotes the aggregation of α‐synuclein splice isoforms via heterogeneous nucleation
FEBS Letters, EarlyView.The aggregation of amyloid‐β (Aβ) and α‐synuclein (αSyn) is associated with Alzheimer's and Parkinson's diseases. This study reveals that Aβ aggregates serve as potent nucleation sites for the aggregation of αSyn and its splice isoforms, shedding light on the intricate interplay between these two pathogenic proteins.
Alexander Röntgen +2 more
wiley +1 more source
Single strand conformation polymorphism (SSCP) detection in six genes in Portuguese indigenous sheep breed [PDF]
Biotechnologie, Agronomie, Société et Environnement, 2001 Evaluation of the genetic diversity for six genes in forty animals of the Portuguese indigenous sheep breed (Ovis aries) ""Churra da Terra Quente"" was done.
Guedes-Pinto H. +3 more
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Frontotemporal Dementia-Associated N279K Tau Mutation Localizes at the Nuclear Compartment
Frontiers in Cellular Neuroscience, 2018 Tau is a microtubule-associated protein that plays an important role in Alzheimer’s disease and related tauopathies. Approximately one-half of all cases of Frontotemporal dementia with parkinsonism-17 (FTDP-17) are caused by mutations in the MAPT gene ...
Maxi L. Ritter +6 more
doaj +1 more source
ERBIN limits epithelial cell plasticity via suppression of TGF‐β signaling
FEBS Letters, EarlyView.In breast and lung cancer patients, low ERBIN expression correlates with poor clinical outcomes. Here, we show that ERBIN inhibits TGF‐β‐induced epithelial‐to‐mesenchymal transition in NMuMG breast and A549 lung adenocarcinoma cell lines. ERBIN suppresses TGF‐β/SMAD signaling and reduces TGF‐β‐induced ERK phosphorylation.
Chao Li +3 more
wiley +1 more source
The manifestation of intonational focus in Castilian Spanish
Catalan Journal of Linguistics, 2003 In this paper we study the phonological manifestation of various intonational focus domains in Castilian Spanish. We propose that downstep is one of the intonational signallers of focus in this language.
Mercedes Cabrera Abreu +1 more
doaj +1 more source
Hard probes in nucleus-nucleus collisions [PDF]
Nuclear Physics A, 1996 15 pages, 8 figures, Latex, uses packages graphicx,rotating,cite, fleqn and the sty file espcrc1_new (included in this submission)
openaire +3 more sources
FEBS Letters, EarlyView.In this work, we reveal how different enzyme binding configurations influence the fluorescence decay of NAD(P)H in live cells using time‐resolved anisotropy imaging and fluorescence lifetime imaging microscopy (FLIM). Mathematical modelling shows that the redox states of the NAD and NADP pools govern these configurations, shaping their fluorescence ...
Thomas S. Blacker +8 more
wiley +1 more source
Nuclear Tau and Its Potential Role in Alzheimer’s Disease
Biomolecules, 2016 Tau protein, found in both neuronal and non-neuronal cells, forms aggregates in neurons that constitutes one of the hallmarks of Alzheimer’s disease (AD).
Mahmoud Bukar Maina +2 more
doaj +1 more source