Results 81 to 90 of about 1,516,986 (362)

Dynamic relocalization of replication origins by Fkh1 requires execution of DDK function and Cdc45 loading at origins

open access: yeseLife, 2019
Chromosomal DNA elements are organized into spatial domains within the eukaryotic nucleus. Sites undergoing DNA replication, high-level transcription, and repair of double-strand breaks coalesce into foci, although the significance and mechanisms giving ...
Haiyang Zhang   +5 more
doaj   +1 more source

Mechanosensing by the nucleus: From pathways to scaling relationships

open access: yesJournal of Cell Biology, 2017
The nucleus is linked mechanically to the extracellular matrix via multiple polymers that transmit forces to the nuclear envelope and into the nuclear interior.
Sangkyun Cho, J. Irianto, D. Discher
semanticscholar   +1 more source

RAD50 missense variants differentially affect the DNA damage response and mitotic progression

open access: yesFEBS Letters, EarlyView.
RAD50 incorporates into the MRN complex and initiates the DNA damage response. Furthermore, RAD50 promotes mitotic progression. RAD50 missense variants capable of forming an MRN complex supported the DNA damage response and mitotic features to different extents in complementation experiments, indicating these functions are separable and might impact ...
Hanna Redeker   +9 more
wiley   +1 more source

Hard probes in nucleus-nucleus collisions [PDF]

open access: yesNuclear Physics A, 1996
15 pages, 8 figures, Latex, uses packages graphicx,rotating,cite, fleqn and the sty file espcrc1_new (included in this submission)
openaire   +3 more sources

Heavy flavor in nucleus-nucleus and proton-nucleus: quenching, flow and correlations [PDF]

open access: yesNuclear and Particle Physics Proceedings, 2016
4 pages, proceedings of "Hard Probes 2015"
Andrea Beraudo   +4 more
openaire   +3 more sources

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Kinds of nucleus for effective pearl cultivation of the pearl oysters, Pinctada fucata [PDF]

open access: yesSongklanakarin Journal of Science and Technology (SJST), 2007
Seeding is the most important aspect of pearl cultivation, and appropriate nucleus can determine the quality of a pearl : nacre secretion and accumulation around the nucleus.
Kanjanachatree, K.   +2 more
doaj  

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Morphopathology of the Prussian carp (Carassius auratus gibelio Bloch, 1782) liver under the effect of allyl acetate

open access: yesRibogospodarsʹka Nauka Ukraïni
Purpose. To assess the liver parenchyma of Prussian carp based on the analysis of histological parameters of the organ, to establish the level of the effect of alylacetate on the physiological status of fish and the degree of their damage.
M. Koziy
doaj   +1 more source

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

open access: yesMolecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez   +17 more
wiley   +1 more source

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