Results 81 to 90 of about 1,534,545 (314)

Antiproton production in p-nucleus and nucleus-nucleus collisions

open access: yesPhysics Letters B, 1991
Abstract The production of antiprotons in proton-nucleus and nucleus-nucleus reactions is analyzed with respect to baryon-baryon production processes. The dynamical evolution of the phase-space distributions is treated on the basis of the Vlasov-Uehling-Uhlenbeck transport theory including explicitly pion, Δ(1232) and N∗(1400) degrees of freedom and ...
G. Batko   +4 more
openaire   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Beta-decay and structure of odd nuclei, suppression of weak forces in nuclei

open access: yesЯдерна фізика та енергетика, 2019
Results of calculations in the framework of the dynamic collective model of probabilities of beta-transitions for more than 20 nuclei with mass numbers from А = 31 to А = 231 with one universal renormalization of weak interaction constants are presented.
A. A. Kurteva, V. E. Mitroshin
doaj   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Single-nucleus chromatin accessibility and transcriptomic characterization of Alzheimer’s disease

open access: yesNature Genetics, 2021
S. Morabito   +9 more
semanticscholar   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

The IMPORTance of the Nucleus during Flavivirus Replication

open access: yesViruses, 2017
Flaviviruses are a large group of arboviruses of significant medical concern worldwide. With outbreaks a common occurrence, the need for efficient viral control is required more than ever.
Adam J. Lopez-Denman, Jason M. Mackenzie
doaj   +1 more source

Heavy flavors in nucleus-nucleus and proton-nucleus collisions [PDF]

open access: yesEPJ Web of Conferences, 2016
A multi-step setup for heavy-flavor studies in high-energy nucleus-nucleus (AA) and proton-nucleus (pA) collisions is presented. The propagation of the heavy quarks in the medium is described in a framework provided by the relativistic Langevin equation, here solved using weak-coupling transport coefficients. Successively, the heavy quarks hadronize in
openaire   +2 more sources

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

Nucleolar dynamics and interactions with nucleoplasm in living cells

open access: yeseLife, 2019
Liquid-liquid phase separation (LLPS) has been recognized as one of the key cellular organizing principles and was shown to be responsible for formation of membrane-less organelles such as nucleoli.
Christina M Caragine   +2 more
doaj   +1 more source

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