Results 171 to 180 of about 566,734 (334)

Astroglial CB1 Reveal Sex‐Specific Synaptic Effects of Amphetamine

open access: yesGlia, Volume 73, Issue 8, Page 1673-1691, August 2025.
Main Points Astroglial CB1 mediate long‐term depression in the NAc through purine release. Amphetamine occludes LTD in male mice by inducing the saturation of A1 receptors. Astroglial CB1 mediate behavioral amphetamine effects in males, but not in females.
Yamuna Mariani   +15 more
wiley   +1 more source

Differential Effects of Prenatal Poly I:C Exposure and Antipsychotics on NMDA/GABA Receptors and GSK3β‐Mediated Signaling in the Dorsal Raphe Nucleus of Female Rats

open access: yesFundamental &Clinical Pharmacology, Volume 39, Issue 4, August 2025.
ABSTRACT Background The dorsal raphe nucleus (DRN) is the origin of the 5‐HT neurotransmission pathways. The 5‐HT, dopamine D2, GABA, and NMDA receptors, as well as the cyclic adenosine monophosphate (cAMP)‐protein kinase A (PKA) and G protein‐independent protein kinase B (PKB/Akt)‐glycogen synthase kinase 3β (GSK3β) signaling, are involved in the ...
Shiyan Chen   +3 more
wiley   +1 more source

Chronic hyperammonemia alters motor and neurochemical responses to activation of group i metabotropic glutamate receptors in the nucleus accumbens in rats in vivo

open access: yesNeurobiology of Disease, 2003
Hyperammonemia leads to altered cerebral function and neurological alterations in patients with hepatic encephalopathy. We studied the effects of hyperammonemia in rats on the modulation by group I metabotropic glutamate receptors (mGluR) of motor and ...
Juan-José Canales   +5 more
doaj  

Nutritionally Responsive PMv DAT Neurons Are Dynamically Regulated During Pubertal Transition

open access: yesThe FASEB Journal, Volume 39, Issue 13, 15 July 2025.
The ventral premammillary nucleus of the hypothalamus plays an essential role in the metabolic control of reproduction. Puberty brings large changes to a subpopulation of PMvLepRb cells expressing the dopamine transporter (PMvDAT). DAT gene expression is higher in prepubertal females than in adults and is regulated by leptin in prepubertal females ...
Cristina Sáenz de Miera   +11 more
wiley   +1 more source

Cellular Organization and Migration Pathways of the Ventricular–Subventricular Zone in the Juvenile Swine Brain (Sus scrofa domesticus)

open access: yesJournal of Comparative Neurology, Volume 533, Issue 7, July 2025.
A detailed structural analysis of the juvenile swine ventricular–subventricular zone reveals four distinct cellular layers and diverse neuroblast migration routes, including pathways toward the olfactory bulb and cortical regions. These features underscore the swine brain's value as a translational model for studying postnatal neurogenesis in large ...
Lucía Inés Torrijos‐Saiz   +6 more
wiley   +1 more source

PASTa: An Open‐Source Analysis and Signal Processing Toolbox for Fiber Photometry Data

open access: yesCurrent Protocols, Volume 5, Issue 7, July 2025.
Abstract Fiber photometry is a rapidly growing technique to record real‐time neural signaling in awake, behaving subjects. However, the processing and analysis of photometry data streams can be complicated, and there is wide divergence in methods across the field.
Rachel M. Donka   +4 more
wiley   +1 more source

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