Results 31 to 40 of about 111,869 (302)
Dynamic risk control by human nucleus accumbens [PDF]
, 2015 Real-world decisions about reward often involve a complex counterbalance of risk and value. Although the nucleus accumbens has been implicated in the underlying neural substrate, its criticality to human behaviour remains an open question, best addressed
Avecillas, J +9 more
core +1 more source
mGluR5 antagonism inhibits cocaine reinforcement and relapse by elevation of extracellular glutamate in the nucleus accumbens via a CB1 receptor mechanism. [PDF]
, 2018 Metabotropic glutamate receptor 5 (mGluR5) antagonism inhibits cocaine self-administration and reinstatement of drug-seeking behavior. However, the cellular and molecular mechanisms underlying this action are poorly understood.
Bi, Guo-Hua +9 more
core +2 more sources
Lithium treatment impacts nucleus accumbens shape in bipolar disorder
NeuroImage: Clinical, 2020 The effects of lithium treatment duration on deep grey matter structures in bipolar disorder are not well known. In this cross-sectional neuroimaging case-control study, we tested the hypothesis that shape characteristics of deep grey matter structures ...
Daniela Vecchio +7 more
doaj +1 more source
Nature Communications, 2018 The nucleus accumbens regulates many behaviours that depend on arousal. Here the authors show that dopamine D1 receptor neurons in the nucleus accumbens can directly regulate wakefulness.
Yan-Jia Luo +10 more
doaj +1 more source
Imaging markers of disability in aquaporin-4 immunoglobulin G seropositive neuromyelitis optica: a graph theory study [PDF]
, 2019 Neuromyelitis optica spectrum disorders lack imaging biomarkers associated with disease course and supporting prognosis. This complex and heterogeneous set of disorders affects many regions of the central nervous system, including the spinal cord and ...
Asseyer, Susanna +10 more
core +2 more sources
A multimodal neuroimaging classifier for alcohol dependence [PDF]
, 2020 With progress in magnetic resonance imaging technology and a broader dissemination of state-of-the-art imaging facilities, the acquisition of multiple neuroimaging modalities is becoming increasingly feasible.
Garbusow, Maria +13 more
core +1 more source
Dnmt3a regulates emotional behavior and spine plasticity in the nucleus accumbens. [PDF]
, 2010 Despite abundant expression of DNA methyltransferases (Dnmts) in brain, the regulation and behavioral role of DNA methylation remain poorly understood. We found that Dnmt3a expression was regulated in mouse nucleus accumbens (NAc) by chronic cocaine use ...
Bolaños, Carlos A +26 more
core +3 more sources
Nucleus Accumbens Invulnerability to Methamphetamine Neurotoxicity [PDF]
ILAR Journal, 2011 Methamphetamine (Meth) is a neurotoxic drug of abuse that damages neurons and nerve endings throughout the central nervous system. Emerging studies of human Meth addicts using both postmortem analyses of brain tissue and noninvasive imaging studies of intact brains have confirmed that Meth causes persistent structural abnormalities.
Donald M, Kuhn +2 more
openaire +2 more sources
Effect of Electrical Stimulation and Lesion of Nucleus Accumbens on EEG of Intact and Addicted Rats [PDF]
Journal of Kerman University of Medical Sciences, 2008 Introduction: The nucleus accumbens is involved in various functions ranging from motivation and reward to feeding and drug addiction. Some researchers have also suggested that this region has some roles in consciousness. In the present study, the effect
M Hosseini +4 more
doaj
Molecular Pain, 2018 Various small molecules act as neurotransmitters and orchestrate neural communication. Growing evidence suggests that not only classical neurotransmitters but also several small molecules, including amino acid derivatives, modulate synaptic transmission.
Moe Watanabe +10 more
doaj +1 more source