Results 31 to 40 of about 376,324 (266)
Molecular Pain, 2018 Various small molecules act as neurotransmitters and orchestrate neural communication. Growing evidence suggests that not only classical neurotransmitters but also several small molecules, including amino acid derivatives, modulate synaptic transmission.
Moe Watanabe +10 more
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NeuroImage: Clinical, 2023 Craving is a core symptom of cocaine use disorder and a major factor for relapse risk. To date, there is no pharmacological therapy to treat this disease or at least to alleviate cocaine craving as a core symptom.
Etna J.E. Engeli +11 more
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Encoding of Aversion by Dopamine and the Nucleus Accumbens [PDF]
Frontiers in Neuroscience, 2012 Adaptive motivated behavior requires rapid discrimination between beneficial and harmful stimuli. Such discrimination leads to the generation of either an approach or rejection response, as appropriate, and enables organisms to maximize reward and minimize punishment.
McCutcheon, James E. +3 more
openaire +4 more sources
Effect of Electrical Stimulation and Lesion of Nucleus Accumbens on EEG of Intact and Addicted Rats [PDF]
Journal of Kerman University of Medical Sciences, 2008 Introduction: The nucleus accumbens is involved in various functions ranging from motivation and reward to feeding and drug addiction. Some researchers have also suggested that this region has some roles in consciousness. In the present study, the effect
M Hosseini +4 more
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The value of extended amygdala structures in emotive effects of narcogenic with diverse chemical structure [PDF]
Research Results in Pharmacology, 2019 Introduction: Studies on the mechanisms of the reinforcing action of opioid and non-opioid narcotics confirmed the existence in the brain of a specialized system named the extended amygdala.
Roman O. Roik +2 more
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Biomolecules, 2022 G protein-coupled trace amine-associated receptors (TAAR) recognize different classes of amine compounds, including trace amines or other exogenous and endogenous molecules.
Anastasia N. Vaganova +4 more
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Sex differences in pre- and post-synaptic glutamate signaling in the nucleus accumbens core
Biology of Sex Differences, 2023 Background Glutamate signaling within the nucleus accumbens underlies motivated behavior and is involved in psychiatric disease. Although behavioral sex differences in these processes are well-established, the neural mechanisms driving these differences ...
Melissa C. Knouse +4 more
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Frontiers in Human Neuroscience, 2009 The ventral striatum / nucleus accumbens has been implicated in the craving for drugs and alcohol which is a major reason for relapse of addicted people. Craving might be induced by drug-related cues.
Hans-Jochen Heinze +14 more
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Dopamine restores reward prediction errors in old age [PDF]
, 2013 Senescence affects the ability to utilize information about the likelihood of rewards for optimal decision-making. Using functional magnetic resonance imaging in humans, we found that healthy older adults had an abnormal signature of expected value ...
Dayan, P. +32 more
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Neuropsychopharmacology Reports, 2019 Aim Repeated psychostimulant drug treatment, including methamphetamine, in rodents readily produces behavioral sensitization, which reflects altered brain function caused by repeated drug exposure.
Yoshiyuki Kasahara +7 more
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