Results 21 to 30 of about 72,699 (283)
Effects of hippocampal damage on reward threshold and response rate during self-stimulation of the ventral tegmental area in the rat [PDF]
, 1999 The main purpose of this study was to explore the role of the hippocampus in motivated behavior. Rats with bilateral excitotoxic lesions of the hippocampus and controls were trained to lever press for electrical stimulation of the ventral tegmental area.
Kelley, Stephen P., Mittleman, Guy
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Nucleus accumbens facilitates nociception [PDF]
Experimental Neurology, 2011 We have previously demonstrated an opioid link in nucleus accumbens (NAc) that mediates antinociception produced by a novel ascending pain modulation pathway. For example, noxious stimulation induces heterosegmental antinociception that is mediated by both mu- and delta-opioid receptors in NAc.
Robert W, Gear, Jon D, Levine
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Nature Communications, 2018 The nucleus accumbens regulates many behaviours that depend on arousal. Here the authors show that dopamine D1 receptor neurons in the nucleus accumbens can directly regulate wakefulness.
Yan-Jia Luo +10 more
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Lithium treatment impacts nucleus accumbens shape in bipolar disorder
NeuroImage: Clinical, 2020 The effects of lithium treatment duration on deep grey matter structures in bipolar disorder are not well known. In this cross-sectional neuroimaging case-control study, we tested the hypothesis that shape characteristics of deep grey matter structures ...
Daniela Vecchio +7 more
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Gustatory reward and the nucleus accumbens [PDF]
Physiology & Behavior, 2006 The concept of reward is central to psychology, but remains a cipher for neuroscience. Considerable evidence implicates dopamine in the process of reward and much of the data derives from the nucleus accumbens. Gustatory stimuli are widely used for animal studies of reward, but the connections between the taste and reward systems are unknown.
R, Norgren, A, Hajnal, S S, Mungarndee
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Molecular Pain, 2018 Various small molecules act as neurotransmitters and orchestrate neural communication. Growing evidence suggests that not only classical neurotransmitters but also several small molecules, including amino acid derivatives, modulate synaptic transmission.
Moe Watanabe +10 more
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The value of extended amygdala structures in emotive effects of narcogenic with diverse chemical structure [PDF]
Research Results in Pharmacology, 2019 Introduction: Studies on the mechanisms of the reinforcing action of opioid and non-opioid narcotics confirmed the existence in the brain of a specialized system named the extended amygdala.
Roman O. Roik +2 more
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Encoding of Aversion by Dopamine and the Nucleus Accumbens [PDF]
Frontiers in Neuroscience, 2012 Adaptive motivated behavior requires rapid discrimination between beneficial and harmful stimuli. Such discrimination leads to the generation of either an approach or rejection response, as appropriate, and enables organisms to maximize reward and minimize punishment.
McCutcheon, James E. +3 more
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Dopamine restores reward prediction errors in old age [PDF]
, 2013 Senescence affects the ability to utilize information about the likelihood of rewards for optimal decision-making. Using functional magnetic resonance imaging in humans, we found that healthy older adults had an abnormal signature of expected value ...
Dayan, P. +32 more
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Effect of Electrical Stimulation and Lesion of Nucleus Accumbens on EEG of Intact and Addicted Rats [PDF]
Journal of Kerman University of Medical Sciences, 2008 Introduction: The nucleus accumbens is involved in various functions ranging from motivation and reward to feeding and drug addiction. Some researchers have also suggested that this region has some roles in consciousness. In the present study, the effect
M Hosseini +4 more
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