Results 21 to 30 of about 111,869 (302)

Tumor suppression and improvement in immune systems by specific activation of dopamine D1-receptor-expressing neurons in the nucleus accumbens

open access: yesMolecular Brain, 2022
Recent research has suggested that the mesolimbic dopamine network that mainly terminates in the nucleus accumbens may positively control the peripheral immune system.
Daisuke Sato   +12 more
doaj   +1 more source

Nucleus accumbens facilitates nociception [PDF]

open access: yesExperimental Neurology, 2011
We have previously demonstrated an opioid link in nucleus accumbens (NAc) that mediates antinociception produced by a novel ascending pain modulation pathway. For example, noxious stimulation induces heterosegmental antinociception that is mediated by both mu- and delta-opioid receptors in NAc.
Robert W, Gear, Jon D, Levine
openaire   +2 more sources

Low frequency deep brain stimulation of nucleus accumbens shell neuronal subpopulations attenuates cocaine seeking selectively in male rats

open access: yesAddiction Neuroscience, 2023
The present study examined the effect of deep brain stimulation (DBS) in the nucleus accumbens shell on cocaine seeking and neuronal plasticity in rats.
Sarah E. Swinford-Jackson   +7 more
doaj   +1 more source

Involvement of the accumbal osteopontin-interacting transmembrane protein 168 in methamphetamine-induced place preference and hyperlocomotion in mice [PDF]

open access: yes, 2017
Chronic exposure to methamphetamine causes adaptive changes in brain, which underlie dependence symptoms. We have found that the transmembrane protein 168 (TMEM168) is overexpressed in the nucleus accumbens of mice upon repeated methamphetamine ...
Fu Kequan   +11 more
core   +3 more sources

Glutamate Afferents From the Medial Prefrontal Cortex Mediate Nucleus Accumbens Activation by Female Sexual Behavior

open access: yesFrontiers in Behavioral Neuroscience, 2019
Low levels of desire and arousal are the primary sexual dysfunctions in women, necessitating neurobiological studies of sexual motivation in female animal models.
Kelsey M. Moore   +5 more
doaj   +1 more source

Behavioral flexibility is increased by optogenetic inhibition of neurons in the nucleus accumbens shell during specific time segments [PDF]

open access: yes, 2014
Behavioral flexibility is vital for survival in an environment of changing contingencies. The nucleus accumbens may play an important role in behavioral flexibility, representing learned stimulus–reward associations in neural activity during response ...
Aquili, Luca *   +4 more
core   +1 more source

Effects of cocaethylene on dopamine and serotonin synthesis in Long–Evans and Sprague–Dawley brains [PDF]

open access: yes, 1998
We examined the behavioral and neurochemical effects of cocaethylene treatment in Long–Evans ( LE). and Sprague–Dawley (SD) rats. Cocaethylene-induced behaviors were significantly less in LE rats.
Baumann, Dr. M.H.   +3 more
core   +1 more source

463 Childhood Emotional Neglect on Nucleus Accumbens Connectivity in Adult Survivors of Trauma

open access: yesJournal of Clinical and Translational Science, 2023
OBJECTIVES/GOALS: Neuroimaging research has found that childhood maltreatment is related to reduced activation of the nucleus accumbens. The long-lasting impact of this relationship is not as well understood.
Michael T. Liuzzi   +3 more
doaj   +1 more source

Dysconnectivity of the parafascicular nucleus in Parkinson's disease: A dynamic causal modeling analysis

open access: yesNeurobiology of Disease, 2023
Background: Recent animal model studies have suggested that the parafascicular nucleus has the potential to be an effective deep brain stimulation target for Parkinson's disease.
Lili Chen   +8 more
doaj   +1 more source

Functional bias of morphine and oliceridine under conditions of minor injury

open access: yesMolecular Pain, 2021
Recent reports suggest pain from surgical injury may influence the risks associated with exposure to opioids. In mice, hind-paw incision attenuates morphine-primed reinstatement due to kappa opioid receptor activation by dynorphin.
Chinwe Nwaneshiudu   +3 more
doaj   +1 more source

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