Results 11 to 20 of about 72,699 (283)

The Effects of Topiramate Applied to the Nucleus Accumbens Region on Morphine Withdrawal Syndrome [PDF]

open access: yesNamık Kemal Tıp Dergisi, 2020
Aim:Nucleus accumbens, one of the nuclei of the basal ganglia, and dopamine, the neurotransmitter play a critical role in opioid dependence and withdrawal. In opioid withdrawal, the importance of neurotransmitters such as glutamate and gamma aminobutyric
Songül ÖZKULA   +9 more
doaj   +2 more sources

The Nucleus Accumbens and Pavlovian Reward Learning [PDF]

open access: yesThe Neuroscientist, 2007
The ability to form associations between predictive environmental events and rewarding outcomes is a fundamental aspect of learned behavior. This apparently simple ability likely requires complex neural processing evolved to identify, seek, and use natural rewards and redirect these activities based on updated sensory information.
Jeremy J, Day, Regina M, Carelli
openaire   +4 more sources

Differential involvement of NMDA, AMPA/kainate, and dopamine receptors in the nucleus accumbens core in the acquisition and performance of pavlovian approach behavior [PDF]

open access: yes, 2001
Stimuli paired with primary rewards can acquire emotional valence and the ability to elicit automatic, Pavlovian approach responses that have been shown to be mediated by the nucleus accumbens. The present experiment investigated the effects of infusions
Rudolf N. Cardinal   +9 more
core   +1 more source

Allopregnanolone and Pentobarbital Infused Into the Nucleus Accumbens Substitute for the Discriminative Stimulus Effects of Ethanol [PDF]

open access: yes, 2001
BACKGROUND: The discriminative stimulus effects of ethanol are mediated in part by the gamma-aminobutyric acid type A (GABA(A)) receptor system. We have previously shown that microinjections of the competitive GABA(A) agonist muscimol in the nucleus ...
Nannini, Michelle A.   +4 more
core   +1 more source

463 Childhood Emotional Neglect on Nucleus Accumbens Connectivity in Adult Survivors of Trauma

open access: yesJournal of Clinical and Translational Science, 2023
OBJECTIVES/GOALS: Neuroimaging research has found that childhood maltreatment is related to reduced activation of the nucleus accumbens. The long-lasting impact of this relationship is not as well understood.
Michael T. Liuzzi   +3 more
doaj   +1 more source

The bivalent side of the nucleus accumbens [PDF]

open access: yesNeuroImage, 2009
An increasing body of evidence suggests that the nucleus accumbens (NAcc) is engaged in both incentive reward processes and in adaptive responses to conditioned and unconditioned aversive stimuli. Yet, it has been argued that NAcc activation to aversive stimuli may be a consequence of the rewarding effects of their termination, i.e., relief. To address
Liat Levita   +5 more
openaire   +3 more sources

The Nucleus Accumbens: A Comprehensive Review [PDF]

open access: yesStereotactic and Functional Neurosurgery, 2015
There is increasing interest among functional neurosurgeons in the potential for novel therapies to impact upon diseases beyond movement disorders and pain. A target of increasing interest is the nucleus accumbens (NAc), which has long been studied as a key brain region mediating a variety of behaviors, including reward and satisfaction. As such, focal
Sanjay, Salgado, Michael G, Kaplitt
openaire   +2 more sources

A case of musical preference for Johnny Cash following deep brain stimulation of the nucleus accumbens

open access: yesFrontiers in Behavioral Neuroscience, 2014
Music is among all cultures an important part of the live of most people. Music has psychological benefits and may generate strong emotional and physiological responses.
Mariska eMantione   +2 more
doaj   +1 more source

Dysconnectivity of the parafascicular nucleus in Parkinson's disease: A dynamic causal modeling analysis

open access: yesNeurobiology of Disease, 2023
Background: Recent animal model studies have suggested that the parafascicular nucleus has the potential to be an effective deep brain stimulation target for Parkinson's disease.
Lili Chen   +8 more
doaj   +1 more source

Functional bias of morphine and oliceridine under conditions of minor injury

open access: yesMolecular Pain, 2021
Recent reports suggest pain from surgical injury may influence the risks associated with exposure to opioids. In mice, hind-paw incision attenuates morphine-primed reinstatement due to kappa opioid receptor activation by dynorphin.
Chinwe Nwaneshiudu   +3 more
doaj   +1 more source

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