Results 41 to 50 of about 111,869 (302)

The value of extended amygdala structures in emotive effects of narcogenic with diverse chemical structure [PDF]

open access: yesResearch Results in Pharmacology, 2019
Introduction: Studies on the mechanisms of the reinforcing action of opioid and non-opioid narcotics confirmed the existence in the brain of a specialized system named the extended amygdala.
Roman O. Roik   +2 more
doaj   +3 more sources

Public Transcriptomic Data Meta-Analysis Demonstrates TAAR6 Expression in the Mental Disorder-Related Brain Areas in Human and Mouse Brain

open access: yesBiomolecules, 2022
G protein-coupled trace amine-associated receptors (TAAR) recognize different classes of amine compounds, including trace amines or other exogenous and endogenous molecules.
Anastasia N. Vaganova   +4 more
doaj   +1 more source

Stability of CART peptide expression in the nucleus accumbens in aging [PDF]

open access: yes, 2015
Aging is accompanied by changes of several anorexigenic and orexigenic neuropeptides expressed in various brain areas that control food intake and these changes correlate with senescent anorexia.
Armbruszt, Simon   +2 more
core   +1 more source

Effort discounting in human nucleus accumbens [PDF]

open access: yesCognitive, Affective, & Behavioral Neuroscience, 2009
A great deal of behavioral and economic research suggests that the value attached to a reward stands in inverse relation to the amount of effort required to obtain it, a principle known as effort discounting. In the present article, we present the first direct evidence for a neural analogue of effort discounting.
Matthew M, Botvinick   +2 more
openaire   +2 more sources

Accumbal-thalamic connectivity and associated glutamate alterations in human cocaine craving: A state-dependent rs-fMRI and 1H-MRS study

open access: yesNeuroImage: Clinical, 2023
Craving is a core symptom of cocaine use disorder and a major factor for relapse risk. To date, there is no pharmacological therapy to treat this disease or at least to alleviate cocaine craving as a core symptom.
Etna J.E. Engeli   +11 more
doaj   +1 more source

Modelling the Effect of Dorsal Raphe Serotonin Neurons on Patience for Future Rewards [PDF]

open access: yes, 2016
Serotonin is a neurotransmitter that is implicated in many basic human functions and behaviours and is closely associated with happiness, depression and reward processing.
Porr, Bernd, Sutherland, Marc
core   +1 more source

Photoperiod Impacts Nucleus Accumbens Dopamine Dynamics

open access: yeseneuro, 2023
AbstractCircadian photoperiod, or day length, changes with the seasons and influences behavior to allow animals to adapt to their environment. Photoperiod is also associated with seasonal rhythms of affective state, as evidenced by seasonality of several neuropsychiatric disorders.
Jameson, Alexis N.   +5 more
openaire   +2 more sources

The Effects of Topiramate Applied to the Nucleus Accumbens Region on Morphine Withdrawal Syndrome

open access: yesNamık Kemal Tıp Dergisi, 2020
Aim:Nucleus accumbens, one of the nuclei of the basal ganglia, and dopamine, the neurotransmitter play a critical role in opioid dependence and withdrawal. In opioid withdrawal, the importance of neurotransmitters such as glutamate and gamma aminobutyric
Songül ÖZKULA   +9 more
doaj   +1 more source

Incentive learning underlying cocaine relapse requires mGluR5 receptors located on dopamine D1 receptor-expressing neurons [PDF]

open access: yes, 2010
Understanding the psychobiological basis of relapse remains a challenge in developing therapies for drug addiction. Relapse in cocaine addiction often occurs following exposure to environmental stimuli previously associated with drug taking.
Bilbao, Ainhoa   +11 more
core   +2 more sources

Counteracting incentive sensitization in severe alcohol dependence using deep brain stimulation of the nucleus accumbens: clinical and basic science aspects

open access: yesFrontiers in Human Neuroscience, 2009
The ventral striatum / nucleus accumbens has been implicated in the craving for drugs and alcohol which is a major reason for relapse of addicted people. Craving might be induced by drug-related cues.
Hans-Jochen Heinze   +14 more
doaj   +1 more source

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