Role of Embinin in the reabsorption of nucleus pulposus in lumbar disc herniation: Promotion of nucleus pulposus neovascularization and apoptosis of nucleus pulposus cells [PDF]
Open Life SciencesAbstract Reabsorption of the nucleus pulposus (NP) in lumbar disc herniation (LDH) refers to the natural absorption or even complete disappearance of LDH. In order to better treat LDH, it is necessary to further study its mechanism and develop new therapeutic drugs.
Meng Yingying +3 more
doaj +3 more sources
Inducing Angiogenesis in the Nucleus Pulposus. [PDF]
Cells, 2023 Bone morphogenetic protein (BMP) gene delivery to Lewis rat lumbar intervertebral discs (IVDs) drives bone formation anterior and external to the IVD, suggesting the IVD is inhospitable to osteogenesis. This study was designed to determine if IVD destruction with a proteoglycanase, and/or generating an IVD blood supply by gene delivery of an angiogenic
Damle SR +11 more
europepmc +4 more sources
Co-culture of Adult Mesenchymal Stem Cells and Nucleus Pulposus Cells in Bilaminar Pellets for Intervertebral Disc Regeneration [PDF]
, 2009 Background: Our goal is to optimize stem cell-based tissue engineering strategies in the context of the intervertebral disc environment. We explored the benefits of co-culturing nucleus pulposus cells (NPC) and adult mesenchymal stem cells (MSC) using a ...
Allon, AA, Lotz, JC, Schneider, RA
core +4 more sources
Acute Herniation of Nondegenerate Nucleus Pulposus: Acute Noncompressive Nucleus Pulposus Extrusion and Compressive Hydrated Nucleus Pulposus Extrusion [PDF]
Veterinary Clinics of North America: Small Animal Practice, 2018 Acute herniation of nondegenerate nucleus pulposus material is an important and relative common cause of acute spinal cord dysfunction in dogs. Two types of herniation of nondegenerate or hydrated nucleus pulposus have been recognized: acute noncompressive nucleus pulposus extrusion (ANNPE) and acute compressive hydrated nucleus pulposus extrusion ...
De Decker, S, Fenn, J
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The Mucopolysaccharides of Nucleus Pulposus. [PDF]
Acta Chemica Scandinavica, 1955 S. Gardell +3 more
openalex +4 more sources
On the Biology of Nucleus Pulposus [PDF]
Acta Orthopaedica Scandinavica, 1951 Bengt Sylvén
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The Proteinpolysaccharides of Bovine Nucleus Pulposus
Journal of Biological Chemistry, 1967 Abstract Bovine nucleus pulposus has been found to be a good source of a series of proteinpolysaccharides containing chondroitin 6-sulfate and keratan sulfate. Six distinct fractions have been separated, totaling 40% of the dry weight of the tissue. Each fraction contains protein, chondroitin 6-sulfate, and keratan sulfate, but the proportions of these
Lawrence Rosenberg +2 more
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Clinical characteristics associated with cervical hydrated nucleus pulposus extrusion in dogs [PDF]
J Vet Intern MedAbstract Background Clinical characteristics of cervical hydrated nucleus pulposus extrusion (HNPE) in dogs compared to other causes of cervical myelopathy are not well described. Hypothesis/Objectives To evaluate for clinical characteristics and mechanical ventilation likelihood associated with HNPE compared to other causes of cervical myelopathy ...
Lin M +4 more
europepmc +2 more sources
Penetration of Glycopeptide Antibiotics in Nucleus Pulposus
Spine, 1993 The penetration of the glycopeptide antibiotics vancomycin and teicoplanin into the nucleus pulposus of rabbits was studied. Blood samples were obtained at 0.5, 1, 4, 8, and 24 hours after intravenous administration of 30 mg/kg vancomycin or 16 mg/kg teicoplanin.
Gaetano J. Scuderi +4 more
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Single‐Cell Analysis Integrated With Machine Learning Elucidates the Mechanisms of Nucleus Pulposus Cells Apoptosis in Intervertebral Disc Degeneration and Therapeutic Interventions [PDF]
JOR SpineIVDD has various NPC subgroups, including HT‐CLNP, fibrous NPC, sticky NPC, regulatory NPC, and steady‐state NPC. Furthermore, numerous immune cell infiltrates, particularly monocytes and macrophages, play a crucial role in the evolution of IVDD. Parthenogenesis' key components are Osthole, Columbianadin, and Bergapten, which absorb IVDD by managing ...
Song C +8 more
europepmc +2 more sources