Results 141 to 150 of about 348,318 (186)

Correction: p16 deficiency attenuates intervertebral disc degeneration by adjusting oxidative stress and nucleus pulposus cell cycle.

Elife
Che H, Li J, Li Y, Ma C, Liu H, Qin J, Dong J, Zhang Z, Xian CJ, Miao D, Wang L, Ren Y.   +11 more
europepmc   +1 more source

In Situ Stress-Dispersing Hydrogel Millispheres via Load Redistribution to Restore Nucleus Pulposus Metabolic Homeostasis. [PDF]

Adv Sci (Weinh)
Li A, Yuan H, Xiao H, Liu X, Cui W.
europepmc   +1 more source

UCHL3 drives ferroptosis in nucleus pulposus cells by deubiquitinating HMGB1 to activate NCOA4-mediated ferritinophagy. [PDF]

Autophagy
Hu T, Cui P, Zhao X, Wang W, Ma Y, Hu X, Zhang H, Fan Z, Wang D, Huang Q, Pan F, Huang H, Cui C, Chen X, Rong Y, Lu S.   +15 more
europepmc   +1 more source

Rapamycin-nanoliposomes target the mTORC1-mediated autophagy-lysosomal and NLRP3/Caspase-1 pathways to inhibit nucleus pulposus cell senescence in intervertebral discs. [PDF]

Bioeng Transl Med
Xing H, Yu M, Liu J, Zhao R, Ai X, Tang R, Zhu T, Li Y, Jiang L, Wei Q, Huang Y, Guo Y, Jiang T, Huang B.   +13 more
europepmc   +1 more source

Editorial Expression of Concern: Integrating bioinformatics and experimental validation to Investigate IRF1 as a novel biomarker for nucleus pulposus cells necroptosis in intervertebral disc degeneration. [PDF]

Sci Rep
Zhou K, Wu S, Wu Z, Ran R, Song W, Dong H, Zhang H.   +6 more
europepmc   +1 more source

Mitigating nucleus pulposus cell senescence in intervertebral disk degeneration: the role of nodakenin in SIRT6 and PINK1/Parkin-associated mitophagy signaling. [PDF]

Cell Mol Biol Lett
Zhou D, Wang L, Zhou Y, Lv J, Song C, Mei Y, Liu T, Wu T, Yu F, Liu Z.   +9 more
europepmc   +1 more source

GPNMB⁺ macrophages promote osteogenic differentiation of nucleus pulposus cells through PDGF signaling in intervertebral disc degeneration. [PDF]

Cell Rep Med
Jiang J, Kong F, Zheng B, Mei Z, Zhu J, Xu X, Pan W, Wang Z, Sun X, Sun K, Huan L, Shi J, Xu H, Guo Y.   +13 more
europepmc   +1 more source

HACE1 alleviates intervertebral disc degeneration by inhibiting ferroptosis in nucleus pulposus cells. [PDF]

Sci Rep
Xia J, Zhang W, Jiang Y, Li T, Dong H, Zhu L, Xia Q, Zhao Y, Yi J, Weng Z, Feng S, Xin Z.   +11 more
europepmc   +1 more source

SENP1 mitigates intervertebral disc degeneration: mechanisms involving suppression of pyroptosis and apoptosis in nucleus pulposus cells. [PDF]

J Orthop Surg Res
Xu Z, Hao K, Zhang T, Yang X, Peng S, Yang G, Zhao J, Zhao Y, Wu D.   +8 more
europepmc   +1 more source

Thrombospondin-4 Regulates Lipopolysaccharide-Induced Apoptosis and Inflammation in Nucleus Pulposus Cells via the Phosphatidylinositol 3-Kinase/Protein Kinase B Pathway. [PDF]

Immun Inflamm Dis
Shu Y, Sun C, Chen S.
europepmc   +1 more source