Results 131 to 140 of about 19,939 (253)
Cell Proliferation, Volume 59, Issue 6, June 2026.Schematic illustration showing that FAP‐α promoted angiogenesis, cytokine release and ECM degradation in the CEP degeneration of the intervertebral disc through upregulating the PI3K/Akt/HIF‐1α/VEGFA pathway. ABSTRACT Intervertebral disc degeneration (IDD) is a primary cause of low back pain, with the development of new blood vessels being a key ...
Hao‐Wei Xu +4 more
wiley +1 more source
, 2006 STUDY DESIGN: The mechanisms behind the formation of a characteristic tissue reaction at the surface of the dorsal root ganglion (DRG) exposed to nucleus pulposus was studied with special reference to apoptosis using electron microscopy and ...
Murata, Y. +4 more
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On the Biology of Nucleus Pulposus [PDF]
Acta Orthopaedica Scandinavica, 1951 openaire +2 more sources
Mitochondrial DNA: A Key Alarmin Igniting the Inflammasome Fire in Health and Disease
Immunology, Volume 178, Issue 2, Page 218-230, June 2026.This review illustrates how mitochondrial DNA, released under cellular stress, acts as a key alarmin that ignites innate immune sensors, particularly inflammasomes and the cGAS‐STING pathway. This paper details how this sustained “inflammasome fire” fuels the progression of diverse inflammatory diseases, including neurodegeneration and metabolic ...
Woo Hyun Park
wiley +1 more source
Dehnel's Phenomenon in Mammals
Mammal Review, Volume 56, Issue 2, June 2026.Some small mammals, which remain active year‐round, undergo reversible reductions in body size, braincase height, and the mass of internal organs, including the brain, from summer to winter. It is called Dehnel's phenomenon. In this review, we summarise knowledge of the mechanisms, adaptive value, and genetic basis of the phenomenon, and show how new ...
Jan R. E. Taylor +2 more
wiley +1 more source
Xinyu Yang,1,2 Qiaochu Li,1,2 Linbang Wang,3 Jiaxing Chen,1,2 Zhengxue Quan1,2 1Department of Orthopedics, the First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, People’s Republic of China; 2Orthopedic Laboratory of Chongqing ...
Yang X, Chen J, Li Q, Quan Z, Wang L
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Orthopaedic Surgery, Volume 18, Issue 6, Page 1133-1143, June 2026.This meta‐analysis finds that anterior cervical discectomy and fusion (ACDF) has a lower initial cost, while cervical disc arthroplasty (CDA) demonstrates a lower risk of reoperation and DVT/PE. CDA's long‐term clinical benefits may offset its higher upfront expense.
Thomas Cho +4 more
wiley +1 more source
, 2015 Discectomy and spinal fusion is the gold standard for spinal surgery to relieve pain. However, fusion can be hindered for yet unknown reasons that lead to non-fusions with pseudo-arthrosis.
Gantenbein, Benjamin +5 more
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Orthopaedic Surgery, Volume 18, Issue 6, Page 1298-1308, June 2026.The formation of lumbar ligamentum flavum cyst (LLFC) represents one of the extremely rare etiologies of lumbar spinal stenosis. Owing to the rarity of such cases and the severe adhesion of LLFC to adjacent tissues, significant challenges are posed to surgical intervention.
Chunjian Gu +3 more
wiley +1 more source
Orthopaedic Surgery, Volume 18, Issue 6, Page 1216-1222, June 2026.The ultrasonic osteotome‐based segmental excision method has the advantages of shorter and controllable operation time, lower blood loss, higher success rate of removal, and lower risk of nerve damage, making it uniquely valuable in the revision surgery for IVDS infection after lumbar fusion.
Junhui Liu +5 more
wiley +1 more source