Results 111 to 120 of about 19,939 (253)

Quantitative Disk and Metabolic Bone PET‐MRI for Understanding Disk‐Endplate Crosstalk in Degeneration of the Lumbar Spine

open access: yesJOR SPINE, Volume 9, Issue 2, June 2026.
ABSTRACT Objectives The aim of this investigation was to explore the association between disk degeneration, quantified by Pfirrmann grades and T1rho as a marker of hydration, and bone remodeling in the vertebral endplate quantified by Na[18F]F uptake on PET.
Virginie Kreutzinger   +7 more
wiley   +1 more source

Soft biomaterials as a substitute for the Nucleus Pulposus [PDF]

open access: yes, 2014
One of the largest health problems faced worldwide, when evaluated by direct (clinical) as well indirect cost (absenteeism), is the degeneration of the intervertebral disc (IVD) that leads to back pain and, potentially disability and individual´s quality
Nabais, João António Pires Miranda
core  

PENEGAKAN DIAGNOSIS DAN PENANGGULANGAN CERVICALYS HERNIATED NUCLEUS PULPOSUS

open access: yes, 2019
This paper examines the exact and precise diagnosis of the Cervicalys Herniatted Nucleus Pulposus (CHNP). CHNP comes from the displacement of the nucleus pulposus in the intervertebral disc at the cervical level, which can cause direct compression of the
Nadeak, Bernadetha
core   +1 more source

Effect of acupotomy intervention on the expressions of proteoglycans in lumbar intervertebral disc of rabbits with lumbar intervertebral disc degeneration

open access: yes针刺研究, 2023
Objective To observe the effect of acupotomy intervention on the expressions of biglycan(BGN), decorin(DCN) and Caspase-3 in lumbar intervertebral disc of rabbits with lumbar intervertebral disc degeneration(LIDD), so as to explore its possible mechanism
HU Jiang-shan   +6 more
doaj  

MRI T2 Relaxation Time of the Intervertebral Disc: Repeatability, the Effect of Time of Day, and Unloaded Rest

open access: yesJOR SPINE, Volume 9, Issue 2, June 2026.
T2 relaxation time is a commonly used MRI measure of intervertebral disc degeneration. This study investigated the repeatability, as well as the effects of time of day and rest on T2 relaxation time. T2 time repeatability was primarily driven by acquisition factors while time of day and rest changes did not exceed within subject variability. Thus, this
Mackenzie N. Conner   +4 more
wiley   +1 more source

Diagnostic Features of Discogenic Low Back Pain: A Narrative Review and Suggested Areas for Future Research and Clinical Practice

open access: yesJOR SPINE, Volume 9, Issue 2, June 2026.
ABSTRACT Background Chronic low back pain is a leading cause of global disability, with discogenic low back pain (DLBP), mechanically stimulated pain arising from the intervertebral disc, representing an important but often under‐recognized subtype. DLBP arises from chronic structural and metabolic changes within the intervertebral disc, leading to ...
William Roger Peters   +2 more
wiley   +1 more source

Herniation of Nucleus Pulposus (Labeled)

open access: yes
Herniation of nucleus ...
Royal College of Surgeons of Ireland (RCSI)
core  

Nucleus pulposus cellular longevity by telomerase gene therapy

open access: yes, 2007
Study designNonviral transfection of nucleus pulposus cells with a telomerase expression construct to assess the effects on cellular lifespan, function, karyotypic stability, and transformation properties.ObjectivesTo investigate whether telomerase gene ...
Webb, Graham   +13 more
core   +1 more source

The Onset of Systemic Lupus Erythematosus Triggers Nucleus Pulposus Cell Pyroptosis to Exacerbate Intervertebral Disc Degeneration

open access: yes
Zhaobai Lao,1,* Xuliang Fang,1,* Shuchao Shen,1,* Yuliang Zhang,2,* Xin Chen,1 Helou Zhang,1 Yishan Bian,1 Chengcong Zhou,1 Ronghua Bao,2 Taotao Xu,3 Hongting Jin,1 Fangda Fu,1 Chengliang Wu,1 Changfeng Hu,4 Hongfeng Ruan1 1Institute of ...
Zhang H   +14 more
core  

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