Results 111 to 120 of about 348,318 (186)

Decellularized Nucleus Pulposus Matrix/Chitosan Hybrid Hydrogels for Nucleus Pulposus Tissue Engineering

open access: yesGlobal Spine Journal
Study Design Basic research Objective To prepared 3 DNPM/chitosan hybrid hydrogels and chose the best DNPM/chitosan hybrid hydrogel for NP tissue engineering.
Yu Zhang MM   +3 more
doaj   +1 more source

The research of transgenic human nucleus pulposus cell transplantation in the treatment of lumbar disc degeneration

open access: yesKaohsiung Journal of Medical Sciences, 2019
The present study determines whether the in vivo injection of TGFβ1 and CTGF mediated by AAV2 to transfect nucleus pulposus cells in degenerative lumbar discs can reverse the biological effects of rhesus lumbar disc degeneration.
Hua‐Cong Wang   +6 more
doaj   +1 more source

Biomechanical, Structural, and Composition Characterization of the Vertebra‐Disc Interface

open access: yesJOR SPINE, Volume 9, Issue 4, December 2026.
ABSTRACT Background The spinal endplate region consists of the cartilage endplate (CEP), bony endplate (BEP), and subchondral trabecular bone (STB). Although this region is often involved in vertebral fractures and disrupted with disc degeneration, the biomechanics of these tissues are incompletely understood. The goal of this study was to characterize
Neilesh R. Frings   +5 more
wiley   +1 more source

Development of kartogenin-conjugated chitosan–hyaluronic acid hydrogel for nucleus pulposus regeneration

open access: yes, 2017
Injectable constructs for in vivo gelation have many advantages in the regeneration of degenerated nucleus pulposus.
Kedong Song   +9 more
core   +1 more source

Neutrophils: Heterogeneity, Biology, Diseases, and Therapeutic Strategies

open access: yesMedComm, Volume 7, Issue 11, November 2026.
Neutrophils exhibit remarkable functional plasticity and play dual roles in tissue protection and disease progression. This review summarizes their key biological functions and highlights the shift from conventional broad‐spectrum interventions to neutrophil‐based drug delivery systems.
Yibing Zhang   +4 more
wiley   +1 more source

IL-1β increases asporin expression via the NF-κB p65 pathway in nucleus pulposus cells during intervertebral disc degeneration

open access: yesScientific Reports, 2017
Disc degeneration (DD) is a multifaceted chronic process that alters the structure and function of intervertebral discs. The pathophysiology of degeneration is not completely understood, but the consensus is that changes in genes encoding extracellular ...
Shengjie Wang   +7 more
doaj   +1 more source

Dorsal ischaemic myelopathy in a dog: A case of unilateral, focal predominantly sensory loss

open access: yesVeterinary Record Case Reports, Volume 14, Issue 4, November 2026.
Abstract A 3‐year‐3‐month‐old, neutered, male Great Dane was presented with peracute left hindlimb monoparesis. Although voluntary movement was present, the dog was effectively non‐ambulatory due to its size. Proprioception, nociception and spinal reflexes were absent in the left hindlimb, localising the lesion to a left L4–S1 myelopathy.
Alexandra Ayoub   +3 more
wiley   +1 more source

Penatalaksanaan Fisioterapi pada Ischialgia e.c Hernia Nucleus Pulposus di RSUD DR. Loekmono Hadi Kudus [PDF]

open access: yes, 2018
THE MANAGEMENT OF PHYSIOTHERAPY TOWARD ISCHIALGIA e.c HERNIA NUCLEUS PULPOSUS IN RSUD DR. LOEKMONO HADI KUDUS (RISKA ANNISA, 2018) Background : Back pain is often felt between the lower back to folding the lower back of lumbar or lumbosacral areas ...
Annisa, Riska
core  

Effect of Keeping Caspar Retractor During Prestige LP Cervical Disc Implantation on Intra‐ and Postoperative Outcomes

open access: yesOrthopaedic Surgery, Volume 18, Issue 11, Page 2428-2439, November 2026.
This study evaluated the effect of retaining the Caspar retractor during Prestige LP implantation in cervical disc arthroplasty (CDA). Although the manufacturer recommends removal, removal caused vertebral instability during endplate drilling/cutting. Retaining the retractor reduced angle fluctuations, implantation time, and fluoroscopy usage, though ...
Xiaoqiang Zhao   +8 more
wiley   +1 more source

Nucleus pulposus-induced apoptosis in dorsal root ganglion following experimental disc herniation in rats

open access: yes, 2006
STUDY DESIGN: The mechanisms behind the formation of a characteristic tissue reaction at the surface of the dorsal root ganglion (DRG) exposed to nucleus pulposus was studied with special reference to apoptosis using electron microscopy and ...
Murata, Y.   +4 more
core  

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