Results 121 to 130 of about 19,939 (253)

Pre‐Conditioned Bone Marrow Mesenchymal Stromal Cell‐Derived Secretome Exerts an Anti‐Inflammatory Effect on Degenerative Nucleus Pulposus Cells In Vitro

open access: yesJOR SPINE, Volume 9, Issue 2, June 2026.
IL‐1β‐preconditioned BM‐MSC‐derived secretome counteracts inflammation‐driven degeneration in hNPCs. BM‐MSCs were preconditioned with IL‐1β (10 ng/mL) for 24 h, and the resulting secretome (BM‐MSCsec) was collected. Degenerative hNPCs cultured in a 3D alginate bead model were exposed to IL‐1β to reproduce an inflammatory degenerative microenvironment ...
Veronica Tilotta   +7 more
wiley   +1 more source

Defining the Human Nucleus Pulposus Microenvironment and Its Impact on Cell Matrix Synthesis and Metabolic Activity

open access: yesJOR SPINE, Volume 9, Issue 2, June 2026.
Human intervertebral disc nutrient microenvironment. Changes observed in microenvironmental profile as a result of degeneration outlined on upper vertebral body with ranges of each species as reported in previous studies. Oxygen, glucose, and lactate gradients are profiled across the lower disc in both healthy and degenerated states.
Niamh Wilson   +6 more
wiley   +1 more source

Durability of Supplemental Nucleus Pulposus Allograft in Patients with Lumbar Discogenic Pain

open access: yes
Shrif Costandi,1 Douglas P Beall,2 Timothy T Davis,3 Kasra Amirdelfan,4 Ramana K Naidu,5 Michael J DePalma,6 Edward S Yoon,7 Jacob W Fleming,8 Jon E Block,9 Nagy Mekhail1 1Pain Management, Cleveland Clinic, Cleveland, OH, USA; 2Comprehensive Specialty ...
Beall DP   +9 more
core  

“Postural Kyphoscoliosis”: an atypical presentation of herniated lumbar nucleus pulposus

open access: yes, 2018
INTRODUCTION: Herniated Nucleus Pulposus is displacement of disc material beyond the intervertebral disc normal margins resulting in pain, weakness or numbness following the myptomal or dermatomal distribution.
Komahen, Colin   +3 more
core  

A Decade of Leadership and Impact: Celebrating 10 Years of the ORS Spine Section

open access: yes
JOR SPINE, Volume 9, Issue 2, June 2026.
Neharika Bhadouria   +43 more
wiley   +1 more source

Effects of Physical Exercise on Pain in Patients With Lumbar Disc Herniation: A Systematic Review and Meta‐Analysis of Randomised Controlled Trials

open access: yesMusculoskeletal Care, Volume 24, Issue 2, June 2026.
ABSTRACT Objective The aim of this study was to analyse the effects of physical exercise on pain in patients with lumbar disc herniation, regardless of whether they had undergone surgery. Methods A meta‐analysis was conducted according to the PRISMA guidelines.
Diego Gama Linhares   +4 more
wiley   +1 more source

Simultaneous Water‐Specific and Fat‐Specific T1 and Fat Fraction Mapping of the Abdomen in Free Breathing Conditions With a Radially Encoded MP2RAGE

open access: yesNMR in Biomedicine, Volume 39, Issue 6, June 2026.
A radially encoded MP2RAGE with alternated fat and water selective pulses to enable 3D abdominal imaging and quantitative parameter mapping in free breathing conditions and simultaneously provide proton‐density fat fraction, water‐specific and fat‐specific T1 maps.
Nadège Corbin   +9 more
wiley   +1 more source

Effect of nucleus pulposus on the stress-strain behaviour of human spinal intervertebral disc

open access: yes, 2009
73 p.Human spinal intervertebral disc (IVD) is 23 in number in the spinal column that connect the adjacent vertebral bodies. The disc is a heterogenous organ consisting of nucleus pulposus (NP), annulus fibrosis and cartilaginous endplates.
Keddal Thulasiraman Ramya.
core  

Axial length, myopia progression, and myopic maculopathy in Stickler syndrome

open access: yesActa Ophthalmologica, Volume 104, Issue 4, Page 423-430, June 2026.
Abstract Purpose We lack knowledge on the potentially progressive nature of and the prevalence of complications to myopia as a characteristic trait of Stickler syndrome. Methods This cross‐sectional study combines ophthalmic examination and medical record data on Danish patients with genetically confirmed Stickler syndrome type 1 (COL2A1) and type 2 ...
Kirstine B. Boysen   +4 more
wiley   +1 more source

Intervertebral disc degeneration in dogs [PDF]

open access: yes, 2010
Back pain is common in both dogs and humans, and is often associated with intervertebral disc (IVD) degeneration. The IVDs are essential structures of the spine and degeneration can ultimately result in diseases such as IVD herniation or spinal ...
Bergknut, Niklas   +3 more
core  

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