Results 151 to 160 of about 482,535 (309)
Chondrocyte‐like nested cells in the aged intervertebral disc are late‐stage nucleus pulposus cells
Aging Cell, 2019 Aging is a major risk factor of intervertebral disc degeneration and a leading cause of back pain. Pathological changes associated with disc degeneration include the absence of large, vacuolated and reticular‐shaped nucleus pulposus cells, and appearance
S. Mohanty +4 more
semanticscholar +1 more source
Resveratrol attenuates inflammation environment-induced nucleus pulposus cell senescence in vitro
Bioscience Reports, 2019 Intervertebral disc degeneration is a disease identified as an inflammation response-participated pathological process. As a classical cellular feature, disc cell senescence is reported to be closely related with disc cell senescence.
Xiaoming Li +6 more
semanticscholar +1 more source
Pain Practice, Volume 25, Issue 7, September 2025.ABSTRACT Introduction Discogenic low back pain can be severely disabling, clinically challenging to diagnose, and expensive to treat. Disc degeneration is characterized by disc dehydration, which diminishes the ability of the disc to distribute pressure, making it more susceptible to damage, and leading to annular tears, fissures, and a higher ...
Wouter K. M. van Os +6 more
wiley +1 more source
COX-2 expression mediated by calcium-TonEBP signaling axis under hyperosmotic conditions serves osmoprotective function in nucleus pulposus cells. [PDF]
, 2018 The nucleus pulposus (NP) of intervertebral discs experiences dynamic changes in tissue osmolarity because of diurnal loading of the spine. TonEBP/NFAT5 is a transcription factor that is critical in osmoregulation as well as survival of NP cells in the ...
Chaiyamongkol, Weera +7 more
core +1 more source
A Comparison of the Antigenic Properties of Nucleus Pulposus and Cartilage Protein Polysaccharide Complexes [PDF]
, 1967 Arsen M. Pankovich, Leonhard Korngold
openalex +1 more source
Injectable Chitosan Hydrogels with Enhanced Mechanical Properties for Nucleus Pulposus Regeneration.
Tissue Engineering. Part A, 2019 IMPACT STATEMENT A thermosensitive chitosan-based hydrogel was developed, which mimics the mechanical properties of the human nucleus pulposus (NP) tissue and provides a suitable environment for seeded NP cells to live and produce glycosaminoglycans ...
Y. Alinejad +6 more
semanticscholar +1 more source
Advanced Science, Volume 12, Issue 29, August 7, 2025.Eosinophils play a crucial role in the progression of temporomandibular joint osteoarthritis (TMJOA). This study demonstrates that eosinophils, induced by OVA/IL‐5, promote Lumican secretion in the synovium, which binds to Annexin A1 in chondrocytes, inhibiting transforming growth factor β2 and Smad2/3 phosphorylation.
Wenqian Chen +12 more
wiley +1 more source
Developmental adaptations to gravity in animals [PDF]
Terrestrial animals have adapted to a constant gravitational stress over millions of years. Tissues of the cardiovascular system and lumbar spine in tall species of animals such as the giraffe are particularly well adapted to high and variable vectors of
Hargens, Alan R.
core +1 more source
Penatalaksanaan Fisioterapi Pada Kasus Ischialgia Akibat Hernia Nukleus Pulposus Dengan Modalitas Short Wave Diathermy Dan Mobilisasi Saraf Di Rsud Sragen [PDF]
, 2015 Latar Belakang :Hernia nucleus pulposus (HNP) adalah suatu nyeri yang disebabkan oleh proses patologik di kolumna vertebralis pada diskus intervertebralis, gejala klinis yang paling sering terjadi ischialgia yaitu nyeri ...
, Maskum Pujianto, SMPh.M.Kes +1 more
core
International Journal for Numerical Methods in Biomedical Engineering, Volume 41, Issue 8, August 2025.The tether pretension within vertebral body tethering is a key parameter that modifies the stress field of the IVD and the contact forces at the facet joints. ABSTRACT Anterior vertebral body tethering (VBT) is a promising technique for the treatment of adolescent idiopathic scoliosis.
Luis Fernando Nicolini +5 more
wiley +1 more source