Results 211 to 220 of about 151,615 (262)
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The Journal of Parasitology, 1977
Immunity to the intracellular protozoan, Toxoplasma gondii, in mice is of the premunition type. Chemoprophylaxis with sulfadiazine normally permits mice to develop immunity to virulent organisms. However, nude (nu/nu) mice, which lack the thymus, failed to develop immunity to toxoplasma during 3 weeks of drug therapy while their hirsute littermates ...
Lindberg, R E, Frenkel, J K
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Immunity to the intracellular protozoan, Toxoplasma gondii, in mice is of the premunition type. Chemoprophylaxis with sulfadiazine normally permits mice to develop immunity to virulent organisms. However, nude (nu/nu) mice, which lack the thymus, failed to develop immunity to toxoplasma during 3 weeks of drug therapy while their hirsute littermates ...
Lindberg, R E, Frenkel, J K
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International Archives of Allergy and Applied Immunology, 2009
IgE levels in nude mice were estimated by the one-step single radial radio-diffusion method using antisera prepared by immunization of guinea pigs with an IgE-rich fraction obtained from sera of normal mice infected with Nippostrongylus brasiliensis and immunized with DNP-ovalbumin in alum gel.
K, Ito +7 more
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IgE levels in nude mice were estimated by the one-step single radial radio-diffusion method using antisera prepared by immunization of guinea pigs with an IgE-rich fraction obtained from sera of normal mice infected with Nippostrongylus brasiliensis and immunized with DNP-ovalbumin in alum gel.
K, Ito +7 more
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Pharmacokinetics of hydroxyurea in nude mice
Anti-Cancer Drugs, 1994Extrachromosomal DNA is the predominant form of gene amplification in human tumors. Hydroxyurea (HU) concentrations of 100-150 microM have been promising in vitro for extrachromosomal DNA elimination. The study objective was to determine the HU dose-concentration relationship in nude mice with HU doses from 0 to 200 mg/kg.
C L, Van den Berg +7 more
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Alloantibody production by nude mice
Cellular Immunology, 1980Abstract Nude mice which have been injected with allogeneic cells are able to make cytotoxic antibodies. These antibodies are predominantly IgM and can be detected with rabbit complement but not with guinea pig complement or by hemagglutination. Antibody may be directed against H-2 determinants but antibody against non-H-2 antigens may also be found ...
B, Kindred, V, Schirrmacher
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Transmission of Leprosy in Nude Mice
The American Journal of Tropical Medicine and Hygiene, 1985Nude mice in groups of 10 were exposed to M. leprae by subcutaneous injection and topically through the nose, lungs, mouth, stomach and skin, broken and unbroken. Animals injected subcutaneously and those topically exposed to M. leprae through the nose developed localized disease which in the course of time became generalized.
S, Chehl, C K, Job, R C, Hastings
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APMIS, 1990
Ossification was studied in cleared fetuses, newborns, 1‐ and 6‐week‐old nu/nu and nu/+ mice of the B 10 LP background. The same ossification pattern was observed in nu/nu and nu/+ in the embryonal period as well as in newborn animals and mice aged 1 or 6 weeks.
K, Smetana, M, Holub
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Ossification was studied in cleared fetuses, newborns, 1‐ and 6‐week‐old nu/nu and nu/+ mice of the B 10 LP background. The same ossification pattern was observed in nu/nu and nu/+ in the embryonal period as well as in newborn animals and mice aged 1 or 6 weeks.
K, Smetana, M, Holub
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Cells Tissues Organs, 1990
In the present study, the morphological aspect of the skin and the hairs of athymic, macroscopically nude mice (NMRI, nu/nu) was investigated by descriptive light- and electron-microscopical methods and compared with the appearance of the skin and the hairs in normally haired mice (NMRI).
P. Köpf-Maier +2 more
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In the present study, the morphological aspect of the skin and the hairs of athymic, macroscopically nude mice (NMRI, nu/nu) was investigated by descriptive light- and electron-microscopical methods and compared with the appearance of the skin and the hairs in normally haired mice (NMRI).
P. Köpf-Maier +2 more
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Growth of Rat-mouse hybridomas in nude mice and nude rats
Journal of Immunological Methods, 1982Athymic (nude) mice and rats were inoculated intraperitoneally with rat-mouse hybridoma cells secreting monoclonal antibodies to rat MHC class I antigens in order to improve the yield of antibodies. Pristane priming and subsequent intraperitoneal injection of the hybridoma cells in to nude mice yielded ascites which contained antibody in high ...
Noeman, S A +4 more
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Nature, 1975
MICE homozygous for the mutation, nude (nu) have been reported to have no thymus1, although they retain a prelymphoid thymic rudiment2. Here, I report the occurrence of individuals that are by external signs (including hairlessness) a nude mutation but possess an apparently normal thymus.
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MICE homozygous for the mutation, nude (nu) have been reported to have no thymus1, although they retain a prelymphoid thymic rudiment2. Here, I report the occurrence of individuals that are by external signs (including hairlessness) a nude mutation but possess an apparently normal thymus.
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ULTRAVIOLET CARCINOGENESIS IN ATHYMIC NUDE MICE
Transplantation, 1987We have investigated the development of skin cancer from exposure to ultraviolet (UV) radiation in C3H- nu/nu nude mice. Nude mice, nude mice reconstituted with thymuses, and nude mouse skin grafted onto normal haired mice had similar tumor incidences and rates of tumor development.
T L, Hoover, W L, Morison, M L, Kripke
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