Results 91 to 100 of about 2,520,215 (291)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Instantaneously Impulsive Stabilization of Mittag–Leffler Numerical Chua’s Oscillator
Fractal and FractionalThe Euler difference approach has become a prevalent tool in the research of integral order differential equations. Nevertheless, a review of the literature reveals a dearth of studies examining fractional order models using the exponential Euler ...
Huizhen Qu, Tianwei Zhang, Jianwen Zhou
doaj +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
The Numerical Applications of (ABM) and (AMM) Numerical Methods on Some Neutrosophic and Dual Problems [PDF]
Neutrosophic Sets and SystemsThe objective of this paper is to present two neutrosophic numerical methods for finding the numerical solutions for some neutrosophic differential equations, where a numerical comparison between AMM and ABM methods with numerical tables that clarify ...
Ahmed Salem Heilat
doaj +1 more source
On the Numerical Approximation of Problems of Impulse Controls [PDF]
, 1975 Problems of impulse control arise in a large number of situations in inventory theory (cf. A. F. VEINOTT Jr.[1]).
openaire +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Some Simple Full-Range Inverse-Normal Approximations
Journal of Numerical Analysis and Approximation TheoryTwo approximations are given for numerically inverting the full range of the standard normal cumulative distribution function. The first approximation has two fitted constants and only modest accuracy but is very simple and well suited for hand ...
Raymond Koopman
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Efficient numerical approximation of a non-regular Fokker-Planck equation associated with first-passage time distributions. [PDF]
BIT Numer Math, 2022 Boehm U, Cox S, Gantner G, Stevenson R.
europepmc +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source