Results 41 to 50 of about 15,083 (198)

Pade Method for Construction of Numerical Algorithms for Fractional Initial Value Problem

Journal of Mathematics, 2020
In this paper, we propose an efficient method for constructing numerical algorithms for solving the fractional initial value problem by using the Pade approximation of fractional derivative operators. We regard the Grunwald–Letnikov fractional derivative
Feng Gao, Chunmei Chi
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

A cell-based model approach to radiation-induced breast cancer development

Frontiers in Public Health
Epidemiological studies, e.g., on atomic bomb survivors, have shown that exposure to ionizing radiation increases the risk of developing breast cancer.
Jins de Jong, Jesse Vogel, Andreas Spörl, Nikolas Pomplun, Christine E. Hellweg   +4 more
doaj   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Numerical and Stability Analysis of Hilfer-Type Fuzzy Fractional Control Systems with Infinite Delay

Fractal and Fractional
This paper presents a unified theoretical and numerical investigation of Hilfer-type fuzzy fractional control systems with infinite continuous delay.
Aeshah Abdullah Muhammad Al-Dosari
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

A Hybrid Numerical Method Combining Legendre Polynomials and Improved Block-Pulse Functions for Solving Linear Systems of Fredholm Integral Equations

Axioms
In order to solve linear systems of Fredholm integral equations, this paper proposes a novel hybrid numerical method that combines improved block-pulse functions with Legendre polynomials.
Mohammed Z. Alqarni, Mohamed A. Ramadan, Heba S. Osheba   +2 more
doaj   +1 more source

The cell-average based neural network for numerical approximation of the nonlinear Schrödinger equation [PDF]

, 2023
Dielan Hu, Changxin Qiu, Bo Yang, Biao Li   +3 more
openalex   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source