Results 121 to 130 of about 87,253,677 (294)

The impact of leukocyte‐associated RNA retention on platelet RNA‐based cancer detection

open access: yesMolecular Oncology, EarlyView.
Platelets carry RNA signals that may help detect cancer, but platelet samples can also retain RNA from white blood cells. We found that this retained white blood cell signal did not significantly affect machine learning cancer classification, suggesting that the cancer‐related RNA signal in platelets is largely independent of leukocyte‐associated RNA ...
Michał Sieczczyński   +12 more
wiley   +1 more source

Solving linear Fredholm-Stieltjes integral equations of the second kind by using the generalized Simpson’s rule

open access: yesMANAS: Journal of Engineering, 2016
In this paper, the generalized Simpson's rule (GSR) is applied to solve linear Fredholm-Stieltjes integral equations of the second kind (LFSIESK). A numerical example is presented to illustrate the method by using Maple.
A. Asanov, S. Yanık
doaj  

Versatile vector tools for efficient protein screening across multiple expression systems

open access: yesFEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu   +5 more
wiley   +1 more source

A regularization–discretization strategy for weakly singular Fredholm integral equations: a Tikhonov–Legendre approach

open access: yesOpen Mathematics
This study presents a new computational technique for solving weakly singular Fredholm integral equations of the first kind, based on a regularization–discretization strategy that combines Tikhonov regularization with Legendre spectral projection methods.
Bechouat Tahar   +4 more
doaj   +1 more source

Numerical solution for fractional Neumann series equations

open access: yesAin Shams Engineering Journal
This study focuses on fractional differential equations defined by the Neumann series operator. The inverse of the fractional integral operator (1−α)I0+αIα is associated with a MABC operator.
Dumitru Baleanu, Babak Shiri
doaj   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

open access: yesFEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão   +3 more
wiley   +1 more source

On asymptotic behaviour at infinity and the finite section for integral equations on the half-line [PDF]

open access: yes, 1994
We consider integral equations on the half-line of the form and the finite section approximation to x obtained by replacing the infinite limit of integration by the finite limit β.
Chandler-Wilde, SN
core   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

open access: yesFEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro   +1 more
wiley   +1 more source

High-Order, Accurate Finite Difference Schemes for Fourth-Order Differential Equations

open access: yesAxioms
This article is devoted to the study of high-order, accurate difference schemes’ numerical solutions of local and non-local problems for ordinary differential equations of the fourth order. Local and non-local problems for ordinary differential equations
Allaberen Ashyralyev   +1 more
doaj   +1 more source

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