Results 101 to 110 of about 73,046 (353)

An innovative iterative approach to solving Volterra integral equations of second kind

open access: yesActa Polytechnica
Many scientists have shown great interest in exploring the realm of second-kind integral equations, offering many techniques for solving them, including exact, approximate, and numerical methods.
Mohammed Abdulshareef Hussein   +2 more
doaj   +1 more source

On Some Results of Investigation of Singular Systems of Integro- Differential Equations Obtained by Yu. Ye. Boyarintsev Research Group

open access: yesИзвестия Иркутского государственного университета: Серия "Математика", 2017
This paper is dedicated to the 110th anniversary of the dean of the mathematical faculty of Irkutsk State University Vladimir Vladimirovich Vasiliev.
M. V. Bulatov, V. F. Chistyakov
doaj   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

Numerical Solution of Weakly Singular Ito-Volterra Integral Equations via Operational Matrix Method based on Euler Polynomials

open access: yesپژوهش‌های ریاضی, 2018
Introduction Many problems which appear in different sciences such as physics, engineering, biology, applied mathematics and different branches can be modeled by using deterministic integral equations.
Farshid Mirzaee, Nasrin Samadyar;
doaj  

Characterising small solutions in delay differential equations through numerical approximations [PDF]

open access: yes, 2003
This paper discusses how the existence of small solutions for delay differential equations can be predicted from the behaviour of the spectrum of the finite dimensional approximations.Manchester Centre for Computational ...
Ford, Neville J., Lunel, Sjoerd M. V.
core  

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Convergence of a collocation scheme for a retarded potential integral equation

open access: yes, 2003
Time domain boundary integral formulations of transient scattering problems involve retarded potential integral equations (RPIEs). Solving such equations numerically is both complicated and computationally intensive, and numerical methods often prove to ...
Duncan, D.B.
core  

Localized boundary-domain integral formulations for problems with variable coefficients

open access: yes, 2002
Specially constructed localized parametrixes are used in this paper instead of a fundamental solution to reduce a boundary value problem with variable coefficients to a localized boundary-domain integral or integro-differential equation (LBDIE or LBDIDE).
S.E. Mikhailov, Mikhailov, SE
core   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

open access: yesMolecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski   +12 more
wiley   +1 more source

New Applications and Improvements of Sinc Functions for Solving a System of Fredholm Integral Equations

open access: yesAxioms
This study introduces two novel methodologies for solving systems of Fredholm integral equations, with particular emphasis on second-kind equations. The first method integrates the Sinc-collocation technique with a newly developed singular exponential ...
Saeed Althubiti, Abdelaziz Mennouni
doaj   +1 more source

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