Results 151 to 160 of about 6,208 (302)

Heterogeneous multiscale methods for stiff ordinary differential equations

, 2005
The heterogeneous multiscale methods (HMM) is a general framework for the numerical approximation of multiscale problems. It is here developed for ordinary differential equations containing different time scales. Stability and convergence results for the
Engquist, Björn,, Tsai, Y. H.
core   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

FEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Numerical methods for singular nonlinear integro-differential equations

, 1987
For the numerical integration of singular nonlinear integro-differential equations we consider fractional linear multistep methods. We prove convergence of these methods and discuss their stability (as an extension of A-stability for stiff differential ...
E. Hairer, Maass, Peter, P. Maass, Hairer, Ernst   +3 more
core   +1 more source

Self-evolving meta-learning neural ordinary differential equations: A novel artificial intelligence-driven approach for solving differential equations

Journal of Algorithms & Computational Technology
Solving ordinary differential equations (ODEs) constitutes a fundamental problem for many scientific and engineering disciplines, particularly for stiff, high-dimensional problems, or problems with changing dynamics.
V Murugesh, M Priyadharshini, R Meganathan, Manoj Singhal, Anand Muni Mishra, Santar Pal Singh, Shashi Prakash Dwivedi, Shubham Sharma, Aseel Smerat, Rajesh Singh, Krishnaraj Ramaswamy   +10 more
doaj   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

Block one-step methods for solving stiff differential equations [PDF]

, 2014
In this research, both stiff ordinary differential equations (ODEs) and parabolic partial differential equation (PDEs) are solved using the A-stable one-step block method with Newton’s iteration with constant step size. Two-point block one-step method
Mohd Zabidi, Muhammad Izzat Zakwan
core  

Innovative Approaches in Differential Equation Analysis Using the Enhanced Differential Transform and Homotopy Perturbation Method

International Journal of Differential Equations
Ordinary differential equations (ODEs) are very basic when it comes to modeling dynamic systems in various fields of science and engineering. However, solving high-dimensional, nonlinear, and stiff ODEs is still a major challenge given the limitations of
V. Murugesh, M. Priyadharshini, Yogesh Kumar Sharma, Umesh Kumar Lilhore, Sarita Simaiya, Lidia Gosy Tekeste   +5 more
doaj   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source