Results 61 to 70 of about 4,735 (217)
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Purpose, Quality, and Value in Critical Realist Research within Nurse Education
Nurse Media: Journal of Nursing, 2019 Background: There have been a wide range of practice fields in nursing research including education; however, the quality of research in these disciplines has often failed to provide a sufficiently robust foundation.
Phil Coleman
doaj +1 more source
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Nursing homes for nursing education
Journal of Professional Nursing, 2023 Dunbar-Jacob, Jacqueline, Fulmer, Terry
openaire +2 more sources
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Fostering Scholarship Capacity: The Experience of Nurse Educators
Canadian Journal for the Scholarship of Teaching and Learning, 2012 In a milieu where traditional views of scholarship are embedded in the culture of educational institutions, and nursing programs in particular, this paper reports on a research project designed to support nurse educators’ capacity to engage in scholarly ...
Penelope A. Cash, Betty Tate
doaj +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Sexual dysfunction in males with systolic heart failure and associated factors
ARYA Atherosclerosis, 2012 Background: Erectile dysfunction (ED) is the inability to achieve or maintain the adequate erection for intercourse. Heart failure is a major risk factor for erectile dysfunction.
Sharareh Zeighami Mohammadi +3 more
doaj
Nursing OpenAim The aim of the study was to explore how students conceptualise and operationalise dignity with confidence in practice through a human rights lens. Design A quantitative study using an online survey questionnaire.
Sheila Douglas +4 more
doaj +1 more source