Results 81 to 90 of about 9,223 (166)

Metabolic Reprogramming and GM‐CSF Secretion in Areca Nut‐Activated Fibroblasts Drive Oral Precancer Progression

open access: yesOral Diseases, EarlyView.
ABSTRACT Objective Oral cancer, with a rising global incidence and poor prognosis, is associated with areca nut use in South and Southeast Asia. In this study, we addressed the effects of areca nut extract (ANE) on oral carcinogenesis by modulating fibroblast behavior in oral tissue.
Yen‐Yun Wang   +9 more
wiley   +1 more source

Changes in the 6th edition of the World Health Organization classification of tumours of the digestive system

open access: yesHistopathology, Volume 88, Issue 7, Page 1295-1314, June 2026.
Changes and new entities in the 6th edition WCT of the digestive system, including structural, molecular, and diagnostic updates to standardize terminology and improve clinical relevance. Epithelial tumours are organized by site; neuroendocrine, mesenchymal and haematolymphoid tumours have dedicated chapters, with refined grading, redefined ...
Mark J Arends   +48 more
wiley   +1 more source

Clinical Course and Impact of Breaks in Therapy for Children With Relapsed/Refractory Solid Tumors

open access: yesPediatric Blood &Cancer, Volume 73, Issue 5, May 2026.
ABSTRACT Introduction Pediatric relapsed or refractory (R/R) solid tumors carry a dismal prognosis, and postrelapse patient experiences are not well described. We present postrelapse outcomes, including number of R/R events and subsequent therapy regimens.
Matthew T. McEvoy   +5 more
wiley   +1 more source

Synchronous Haemorrhagic Tumors of the Anterior Maxilla and Oropharynx

open access: yesClinical Case Reports, Volume 14, Issue 5, May 2026.
Photomicrograph of a low‐power view of partially ulcerated squamous mucosa with underlying vascular proliferation showing anastomosing vascular channels. Hematoxylin and eosin stain. Magnification ×20. ABSTRACT Oral epithelioid angiosarcoma arising in the oral cavity is exceptionally rare.
Brian Maloney   +5 more
wiley   +1 more source

Greater Attention to Gingival Cancer and Floor of Mouth Cancer: Based on a Retrospective Analysis of Oral Cancer Across Different Subsites

open access: yesHead &Neck, Volume 48, Issue 5, Page 1351-1360, May 2026.
ABSTRACT Background The gingiva and floor of the mouth are distinct subsites, and oral squamous cell carcinoma (OSCC) originating in these locations warrants further indepth understanding. Methods This study enrolled patients with OSCC from 2000 to 2020, and analyzed the clinicopathological characteristics.
Hao Li   +12 more
wiley   +1 more source

A rare case of P63-negative sinonasal NUT midline carcinoma in the elderly

open access: yesEuropean Journal of Case Reports in Internal Medicine
A nuclear protein in testis (NUT) midline carcinoma arises from squamous cells and is often located in the head, neck, and lungs. This report focuses on the negative p63 mutation and older age at the diagnosis of a NUT carcinoma, which has significant ...
Anum Qayum   +6 more
doaj   +1 more source

Early‐Onset Digestive System Cancers: Risk Factors and Clinicopathological and Molecular Features Across Organ Sites

open access: yesCancer Science, Volume 117, Issue 5, Page 1223-1234, May 2026.
Shared risk factors, clinical features, and tumor characteristics across multiple early‐onset cancer types are shown in this Graphical Abstract. Integrative approaches combining molecular pathology, oncology, and population sciences offer opportunities to clarify underlying mechanisms and help us develop preventive strategies for early‐onset cancers ...
Nobuhiro Nakazawa   +17 more
wiley   +1 more source

Midline carcinoma with t(15;19) and BRD4-NUT fusion oncogene in a 30-year-old female with response to docetaxel and radiotherapy

open access: yesBMC Cancer, 2006
Background Poorly differentiated midline carcinoma with a translocation between chromosomes 15 and 19, i.e. t(15;19), has been recognized as a distinct clinical entity for over a decade.
Dahlén Anna   +5 more
doaj   +1 more source

A rare case of NUT midline carcinoma

open access: yesGynecologic Oncology Case Reports, 2013
► NUT midline carcinoma is a rare and aggressive cancer arising in midline structures and is of squamous cell lineage. ► Diagnosis by use of molecular tests is possible with clinical suspicion. ► NUT midline carcinoma is refractory to conventional treatments, but understanding of molecular alterations may lead to an effective therapy.
Ball, Allison   +5 more
openaire   +2 more sources

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