Results 81 to 90 of about 9,390 (183)
Journal of Oral Pathology &Medicine, EarlyView.ABSTRACT Background Early‐onset oral squamous cell carcinoma (EO‐OSCC), commonly defined as occurring in individuals under 50 years of age, is increasingly recognized as a potentially distinct clinical subset with differences in exposure patterns and tumor biology compared with conventional oral squamous cell carcinoma (OSCC).
Gennaro Musella +8 more
wiley +1 more source
Models of Oral Epithelial Dysplasia: A Systematic Review and Temporal Analysis
Journal of Oral Pathology &Medicine, EarlyView.ABSTRACT Background Oral squamous cell carcinoma (OSCC) is the most common malignancy of the head and neck, associated with substantial morbidity and mortality worldwide. Oral epithelial dysplasia (OED) can precede OSCC, offering a critical window for preventive and therapeutic intervention.
Zilefac Brian Ngokwe +4 more
wiley +1 more source
Journal of Oral Pathology &Medicine, EarlyView.ABSTRACT Background Early diagnosis is crucial in improving oral cancer outcomes. Patient education materials support timely recognition and management. However, these resources are often written above recommended reading levels, beyond patients' health literacy and limiting accessibility.
Agata Baczynska +5 more
wiley +1 more source
Oral Diseases, EarlyView.ABSTRACT Background Histological grading of oral epithelial dysplasia (OED) is used for predicting malignant transformation risk. However, grading is associated with significant subjectivity and observer variability leading to inconsistency in prognosis prediction.
Hanya Mahmood +10 more
wiley +1 more source
Oral Diseases, EarlyView.ABSTRACT Objective Oral cancer, with a rising global incidence and poor prognosis, is associated with areca nut use in South and Southeast Asia. In this study, we addressed the effects of areca nut extract (ANE) on oral carcinogenesis by modulating fibroblast behavior in oral tissue.
Yen‐Yun Wang +9 more
wiley +1 more source
A rare case of P63-negative sinonasal NUT midline carcinoma in the elderly
European Journal of Case Reports in Internal MedicineA nuclear protein in testis (NUT) midline carcinoma arises from squamous cells and is often located in the head, neck, and lungs. This report focuses on the negative p63 mutation and older age at the diagnosis of a NUT carcinoma, which has significant ...
Anum Qayum +6 more
doaj +1 more source
Updates on Mediterranean diet and health status: active ingredients and pharmacological mechanisms
British Journal of Pharmacology, Volume 183, Issue 13, Page 3484-3502, July 2026.The Mediterranean diet (MedDiet) is among the most extensively studied dietary patterns and has been consistently associated with reduced risk of all‐cause mortality, cardiovascular disease, metabolic disorders, cognitive decline and several types of cancers.
Lukas Schwingshackl +3 more
wiley +1 more source
Case report: Diagnosis of NUT carcinoma of hepatic origin by next-generation sequencing
Frontiers in OncologyNUT carcinoma is a rare subcategory of squamous cell carcinoma. The latter is primarily characterized by the fusion of the coding sequence NUTM1 on chromosome 15q14 with BRD4 or BRD3, both of which are acetyl-histone binding bromodomains.
Bach Ardalan +3 more
doaj +1 more source
SIRT1: Protean roles at the nexus of health, disease, and therapeutics
Journal of Cell Communication and Signaling, Volume 20, Issue 2, June 2026.SIRT1 serves as a central regulator linking metabolism, stress responses, and disease. It influences diverse processes, including transcriptional and posttranscriptional gene expression and protein activity, inflammation, mitochondrial function, and cell survival, through the deacetylation of multiple protein targets. While SIRT1 often plays protective
Brahim Chaqour
wiley +1 more source
BMC Cancer, 2006 Background Poorly differentiated midline carcinoma with a translocation between chromosomes 15 and 19, i.e. t(15;19), has been recognized as a distinct clinical entity for over a decade.
Dahlén Anna +5 more
doaj +1 more source