Results 61 to 70 of about 9,223 (166)

Skeletal muscle status and malnutrition as predictors of short‐term radiotherapy response and oral mucositis in head and neck cancer

Precision Radiation Oncology, EarlyView.
Baseline muscle mass and malnutrition were not decisive for short‐term radiotherapy outcomes in advanced head‐and‐neck cancer, yet diminished hand‐grip strength signaled poorer tumor response. This suggests that functional muscle metrics may serve as an accessible, actionable biomarker warranting validation in larger longitudinal cohorts.
Haomiao Zhang, Xiaonan Hu, Junying Zhao, Mingxin Zhang, Yang You, Wencheng Shao, Lili Yu   +6 more
wiley   +1 more source

Tracheal resection and reconstruction under non-intubated anesthesia for nuclear protein in testis carcinoma: a case report

World Journal of Surgical Oncology
Background Nuclear protein in testis (NUT) carcinoma is a rare and highly aggressive solid tumor with a poor overall survival outcome. There’s no recognized treatment or consensus on the management for NUT carcinoma.
Zijian Li, Chudong Wang, Yuxuan Li, Rui Wang, Yun Juan Liang, Shuben Li   +5 more
doaj   +1 more source

Genomic profiling of solid tumors harboring BRD4-NUT and response to immune checkpoint inhibitors

Translational Oncology, 2021
Background: The translocation t(15:19) produces the oncogenic BRD4-NUT fusion which is pathognomonic for NUT carcinoma (NC), which is a rare, but extremely aggressive solid tumor.
Jonathan W. Riess, Shaila Rahman, Waleed Kian, Claire Edgerly, Andreas M. Heilmann, Russell Madison, Shakti H. Ramkissoon, Shai Shlomi Klaitman, Jon H. Chung, Sally E. Trabucco, Dexter X. Jin, Brian M. Alexander, Samuel J. Klempner, Lee A. Albacker, Garrett M. Frampton, Laila C. Roisman, Vincent A. Miller, Jeffrey S. Ross, Alexa B. Schrock, Jeffrey P. Gregg, Nir Peled, Ethan S. Sokol, Siraj M. Ali   +22 more
doaj   +1 more source

A sample size analysis of a mathematical model of longitudinal tumor volume and progression‐free survival for Bayesian individual dynamic predictions in recurrent high‐grade glioma

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 495-509, March 2025.
Abstract Patients with recurrent high‐grade glioma (rHGG) have a poor prognosis with median progression‐free survival (PFS) of <7 months. Responses to treatment are heterogenous, suggesting a clinical need for prognostic models. Bayesian data analysis can exploit individual patient follow‐up imaging studies to adaptively predict the risk of progression.
Daniel J. Glazar, Solmaz Sahebjam, Hsiang‐Husan M. Yu, Dung‐Tsa Chen, Menal Bhandari, Heiko Enderling   +5 more
wiley   +1 more source

NUT carcinoma

Indian Journal of Pathology and Microbiology, 2023
Mohammed, Shahin, Krushna Kumari, Sahoo, Ephraim, Rebba, Mahesh, Sultania, Madhabananda, Kar, Mukund, Sable   +5 more
  +5 more sources

A Retrospective Study of Two Mandibulectomy Approaches for T3‐Stage Lower Gingival Carcinoma

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective This study retrospectively analyzes two mandibular resection techniques for T3‐stage lower gingival carcinoma, aiming to compare their impact on patient prognosis. Methods Retrospective cohort study. Data from 78 cases of T3‐stage lower gingival carcinoma involving the mandible were reviewed in our Department of Head and Neck Surgery.
Hang Ling, Wen‐Xiao Huang, Wai‐Sheng Zhong, Hai‐Lin Zhang, Hong Peng, Jie Chen, Ping‐Qing Tan   +6 more
wiley   +1 more source

Neuroendocrine and squamous cell phenotypes of NUT carcinoma are potential diagnostic pitfalls that discriminating it from mimickers, such as small cell and squamous cell carcinoma

Diagnostic Pathology
Introduction NUT carcinoma is a rare cancer associated with a poor prognosis. Because of its rarity, its diagnosis is challenging and is usually made by excluding other diagnoses. Immunohistochemical analysis is a reliable technique that contributes to a
Hironori Ninomiya, Yukiko Sato, Kentaro Inamura, Akito Dobashi, Kengo Takeuchi, Hiroki Mitani, Mingyon Mun, Makoto Nishio, Yuichi Ishikawa   +8 more
doaj   +1 more source

A Review of NUT Midline Carcinoma [PDF]

Head and Neck Pathology, 2011
Nut midline carcinomas are uncommon carcinomas characterized by chromosomal rearrangements that involve the gene encoding the nuclear protein of the testis (NUT). This article reviews the clinicopathologic features of these malignancies. Ancillary testing is discussed as well as the pathologic differential diagnosis.
openaire   +2 more sources

Voice of Asia: Provision of Patient‐Centered Care in Oral Cavity Cancer: A Qualitative Study With Patients, Caregivers, and Healthcare Professionals in Five Asia‐Pacific Regions

Asia-Pacific Journal of Clinical Oncology, EarlyView.
The study identified key barriers to optimal patient‐centered care, including delayed diagnosis due to awareness and stigma‐related barriers among patients and caregivers, and opportunities to enhance multidisciplinary coordination. Resource limitations impacted nursing and psychosocial support, while access to support care varied across regions.
Edwin Pun Hui, Puma Sundaresan, Hye Ryun Kim, Khoi Tuan Nguyen, Tracey E Nicholls, Hai‐Ling Teng, Yu‐Chung Li, Ying Jie Yew, Regina Gowindah, Con Stylianou, Pei‐Jen Lou   +10 more
wiley   +1 more source

NUT Midline Carcinomas of the Sinonasal Tract [PDF]

American Journal of Surgical Pathology, 2012
NUT midline carcinoma (NMC) is a highly lethal tumor defined by translocations involving the NUT gene on chromosome 15q14. NMC involves midline structures including the sinonasal tract, but its overall incidence at this midline site and its full morphologic profile are largely unknown because sinonasal tumors are not routinely tested for the NUT gene ...
Justin A, Bishop, William H, Westra
openaire   +2 more sources