Results 61 to 70 of about 9,420 (171)

NUT carcinoma: A rare presentation of a chest mass with hypercalcemia in a pediatric patient

Human Pathology Reports, 2023
The most common etiologies for chest masses in children include neurogenic tumors, germ cell tumors, leukemia/lymphoma and cysts [1]. Hypercalcemia of malignancy can complicate the clinical course, but is rare in children and most likely to occur in ...
Amanda K. Johnson, Travis Johnson, Katrina Winsnes, Jessica L. Davis   +3 more
doaj   +1 more source

NUT Midline Carcinomas of the Sinonasal Tract [PDF]

American Journal of Surgical Pathology, 2012
NUT midline carcinoma (NMC) is a highly lethal tumor defined by translocations involving the NUT gene on chromosome 15q14. NMC involves midline structures including the sinonasal tract, but its overall incidence at this midline site and its full morphologic profile are largely unknown because sinonasal tumors are not routinely tested for the NUT gene ...
Justin A, Bishop, William H, Westra
openaire   +2 more sources

Primary Nodal Poroid Hidradenocarcinoma With YAP1::NUTM1 Fusion: Report of a Rare Case

Journal of Cutaneous Pathology, EarlyView.
ABSTRACT Poroid hidradenocarcinoma is a rare malignant sweat gland neoplasm. Although primary nodal hidradenoma has been reported, primary nodal poroid hidradenocarcinoma has not been described. We report a case of a 56‐year‐old man presenting with a nontender 5.5 cm mass within the axillary lymph node, and no identifiable primary cutaneous lesion on ...
Niloufar Hosseini, Omar Sbeanaty, William J. Phillips, Bryan Lo, Sandeep Sehdev, Thomas Brenn   +5 more
wiley   +1 more source

NUT carcinoma

Indian Journal of Pathology and Microbiology, 2023
Mohammed, Shahin, Krushna Kumari, Sahoo, Ephraim, Rebba, Mahesh, Sultania, Madhabananda, Kar, Mukund, Sable   +5 more
  +5 more sources

Neuroendocrine and squamous cell phenotypes of NUT carcinoma are potential diagnostic pitfalls that discriminating it from mimickers, such as small cell and squamous cell carcinoma

Diagnostic Pathology
Introduction NUT carcinoma is a rare cancer associated with a poor prognosis. Because of its rarity, its diagnosis is challenging and is usually made by excluding other diagnoses. Immunohistochemical analysis is a reliable technique that contributes to a
Hironori Ninomiya, Yukiko Sato, Kentaro Inamura, Akito Dobashi, Kengo Takeuchi, Hiroki Mitani, Mingyon Mun, Makoto Nishio, Yuichi Ishikawa   +8 more
doaj   +1 more source

Genomic profiling of solid tumors harboring BRD4-NUT and response to immune checkpoint inhibitors

Translational Oncology, 2021
Background: The translocation t(15:19) produces the oncogenic BRD4-NUT fusion which is pathognomonic for NUT carcinoma (NC), which is a rare, but extremely aggressive solid tumor.
Jonathan W. Riess, Shaila Rahman, Waleed Kian, Claire Edgerly, Andreas M. Heilmann, Russell Madison, Shakti H. Ramkissoon, Shai Shlomi Klaitman, Jon H. Chung, Sally E. Trabucco, Dexter X. Jin, Brian M. Alexander, Samuel J. Klempner, Lee A. Albacker, Garrett M. Frampton, Laila C. Roisman, Vincent A. Miller, Jeffrey S. Ross, Alexa B. Schrock, Jeffrey P. Gregg, Nir Peled, Ethan S. Sokol, Siraj M. Ali   +22 more
doaj   +1 more source

Diagnosis of NUT Midline Carcinoma Using a NUT-specific Monoclonal Antibody [PDF]

American Journal of Surgical Pathology, 2009
NUT midline carcinoma (NMC) is a uniformly lethal malignancy that is defined by rearrangement of the nuclear protein in testis (NUT) gene on chromosome 15q14. NMCs are morphologically indistinguishable from other poorly differentiated carcinomas, and the diagnosis is usually made currently by fluorescence in situ hybridization (FISH).
Herbert, Haack, Laura A, Johnson, Christopher J, Fry, Katherine, Crosby, Roberto D, Polakiewicz, Edward B, Stelow, Seung-Mo, Hong, Brian E, Schwartz, Michael J, Cameron, Mark A, Rubin, Martin C, Chang, Jon C, Aster, Christopher A, French   +12 more
openaire   +2 more sources

S1 guideline sweat gland carcinoma

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary The current classification of sweat gland carcinomas is based on histomorphological characteristics and distinguishes between more than 20 entities. Most patients are older, but some subtypes also affect middle‐aged and younger patients. The majority of tumors arise de novo. Sweat gland carcinomas have nonspecific clinical features.
Mirjana Ziemer, Michael Erdmann, Abbas Agaimy, Jürgen C. Becker, Almut Böer‐Auer, Doris Helbig, Cornelia Erfurt‐Berge, Alexander Frisman, Conrad Hempel, Ulrike Leiter, Friedegund Meier, Thomas Mentzel, Lara Racz, Silke Redler, Stefan Schliep, Clemens Seidel, Alpaslan Tasdogan, Jochen Utikal, Carsten Weishaupt, Selma Ugurel   +19 more
wiley   +1 more source

A rare case of NUT midline carcinoma

Gynecologic Oncology Case Reports, 2013
► NUT midline carcinoma is a rare and aggressive cancer arising in midline structures and is of squamous cell lineage. ► Diagnosis by use of molecular tests is possible with clinical suspicion. ► NUT midline carcinoma is refractory to conventional treatments, but understanding of molecular alterations may lead to an effective therapy.
Ball, Allison, Bromley, Amy, Glaze, Sarah, French, Christopher A., Ghatage, Prafull, Köbel, Martin   +5 more
openaire   +2 more sources

Adverse Oral Health in Older Adults With Head and Neck Cancer (And Oral Potentially Malignant Disorders): A Systematic Review

Gerodontology, EarlyView.
ABSTRACT Objective This systematic review evaluated oral health, including oral health‐related quality of life (OHRQoL), in older adults with head and neck cancer (HANC) or oral potentially malignant disorders (OPMDs). The PICO/PECO focus question for this study was: ‘What is the incidence/prevalence of adverse oral health (O) among people aged 60 ...
Ciaran Moore, Niamh Walls, Shaima Abujaber, Amanda Willis, Finbarr Allen, Gerry McKenna   +5 more
wiley   +1 more source