Results 41 to 50 of about 9,390 (183)
NUT carcinoma: a rare and devastating neoplasm [PDF]
BMJ Case Reports, 2018 A 45-year-old woman with no significant medical history had 1 month of productive cough empirically treated with azithromycin and dyspnoea on exertion. She was never a smoker and denied any constitutional symptoms, including unexpected weight loss. A CT of the chest was performed after she developed haemoptysis, which demonstrated a 6.3×4.6 cm right ...
Shinban Liu, George Ferzli
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NUT Midline Carcinoma: A Rare Malignancy [PDF]
Cancer Control, 2017 Nuclear protein of the testis (NUT) midline carcinoma can present in the head, neck, and mediastinum. In general, it presents in young adult men and has a poor prognosis. We report on a case of NUT midline carcinoma of the mediastinum in a man 27 years of age without any prior malignancy.
Sameer, Al Diffalha +4 more
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p63-negative thoracic NUT carcinoma - A potential diagnostic pitfall
Indian Journal of Pathology and MicrobiologyNUT carcinoma is a rare, aggressive, undifferentiated carcinoma characterized by NUTM1 gene rearrangement. It was formerly termed NUT midline carcinoma due to its propensity to occur in midline anatomical structures.
K R Anila +3 more
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Radiologic Manifestations of Pulmonary Nuclear Protein in Testis Midline Carcinoma: A Case Report
Journal of the Korean Society of Radiology, 2023 Nuclear portein in testis (NUT) midline carcinoma is a very rare and low-differentiating malignant epithelial tumor that differentiates very aggressively and has poor prognosis. NUT midline carcinoma occurring in the lungs in particular can be confused
Jung A Kim +6 more
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Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
A Review of NUT Midline Carcinoma [PDF]
Head and Neck Pathology, 2011 Nut midline carcinomas are uncommon carcinomas characterized by chromosomal rearrangements that involve the gene encoding the nuclear protein of the testis (NUT). This article reviews the clinicopathologic features of these malignancies. Ancillary testing is discussed as well as the pathologic differential diagnosis.
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Diagnostic Cytopathology, EarlyView.ABSTRACT Fine‐needle aspiration cytology specimens are frequently utilized for ancillary studies to identify diagnostic and prognostic information. This case highlights diagnostic pitfalls and challenges in diagnosing NUTM1‐rearranged neoplasia on pancreatic cytology.
Terrance J. Lynn
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NUT midline carcinomas in the thymic region [PDF]
Modern Pathology, 2014 NUT midline carcinomas (NMCs) are rare tumors described predominantly in the pediatric age group. We recently reported two cases of these tumors occurring in the thymic region. In order to establish the true incidence of these tumors, we examined a large series of thymic carcinomas for morphological features of NUT tumor and further assessed the ...
Yesim, Gökmen-Polar +4 more
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Head &Neck, EarlyView.ABSTRACT Background Sinonasal malignancies (SNM) are rare, heterogeneous tumors with poor prognosis. There is an unmet need to improve treatment outcomes. Despite advances in imaging and molecular classification, optimal curative radiotherapy (RT) strategies remain undefined.
M. de Ridder +11 more
wiley +1 more source
Areca nut is associated with younger age of diagnosis, poor chemoradiotherapy response, and shorter overall survival in esophageal squamous cell carcinoma. [PDF]
PLoS ONE, 2017 OBJECTIVE:Areca nut chewing is carcinogenic to humans. However, little is known about the impact of areca nut chewing on esophageal squamous cell carcinoma (ESCC). METHODS:We retrospectively reviewed 286 ESCC patients who received surgery or preoperative
Chang-Han Chen +6 more
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