Results 41 to 50 of about 634,585 (195)
Supercharging BRD4 with NUT in carcinoma
Oncogene, 2021 NUT carcinoma (NC) is an extremely aggressive squamous cancer with no effective therapy. NC is driven, most commonly, by the BRD4-NUT fusion oncoprotein. BRD4-NUT combines the chromatin-binding bromo- and extraterminal domain-containing (BET) protein, BRD4, with an unstructured, poorly understood protein, NUT, which recruits and activates the histone ...
Kyle P. Eagen, Christopher A. French
openaire +3 more sources
Thoracic Cancer, 2020 Background Nuclear protein in testis (NUT) carcinoma is a rare tumor associated with NUT rearrangement that can present as poorly differentiated to undifferentiated carcinoma, with or without abrupt squamous differentiation.
Yoon Ah Cho +5 more
doaj +1 more source
Thoracic Cancer, 2020 Nuclear protein in testis (NUT) carcinoma is a rare, aggressive carcinoma that is a diagnostic challenge for pathologists. Here, we report a case of NUT carcinoma in a 63‐year‐old woman with uncommon immunohistochemical results. The initial bronchoscopic
Hwa Jin Cho, Hyun‐Kyung Lee
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NUT carcinoma arising from the parotid gland: a case report and review of the literature [PDF]
, 2021 NUT carcinoma is an aggressive carcinoma with an overall poor survival outcome. The mediastinum and head and neck area, especially the sinonasal region, are among the common sites of disease.
Da Forno, Philip
core +3 more sources
P63-negative pulmonary NUT carcinoma arising in the elderly: a case report
Diagnostic Pathology, 2020 Background Pulmonary NUT carcinoma is rare, but lethal, thus, must not be overlooked. The definitive diagnosis is made by a NUT monoclonal antibody or gene analysis, but these are not always routinely available.
Satoe Numakura +12 more
doaj +1 more source
Frontiers in Oncology, 2023 BackgroundNuclear protein of the testis (NUT) carcinoma is a rare subset of poorly differentiated, highly aggressive malignancy defined by NUTM1 gene rearrangements.
Huahua Jiang +12 more
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Challenges and Opportunities in NUT Carcinoma Research [PDF]
Genes, 2021 NUT carcinoma (NC) is a type of aggressive cancer driven by chromosome translocations. Fusion genes between a DNA-binding protein, such as bromodomain and extraterminal domain (BET) proteins, and the testis-specific protein NUTM1 generated by these translocations drive the formation of NC.
Bin Gu, Maxwell C. Hakun
openaire +2 more sources
Beyond labelling: What strategies do nut allergic individuals employ to make food choices? A qualitative study [PDF]
, 2013 This article is made available through the Brunel Open Access Publishing Fund. Copyright @ 2013 Barnett et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use ...
Raats Monique M. +28 more
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Clinical Diagnosis and Treatment of Primary Lung NUT Midline Carcinoma
Zhongliu Fangzhi Yanjiu, 2019 The nuclear protein of the testis (NUT) midline carcinoma is a highly aggressive malignant epithelial neoplasm. The tumor is characterized by chromosome rearrangement of the NUT gene on 15q14, which results in the expression of NUT protein outside the ...
HE Xinyue, SHI Lei, ZHANG Ziyue, LI Jia
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Betel Nut and Arecoline: Past, Present, and Future Trends [PDF]
Innovations in Digital Health, Diagnostics, and Biomarkers, 2022 The areca nut, commonly known as betel nut, has been the subject of consistent scientific study over the past 5 decades. Betel nut is a natural compound chewed for its psychostimulating effects.
Zisis Kozlakidis +2 more
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