Results 31 to 40 of about 9,390 (183)
Frontiers in Oncology, 2023 BackgroundNuclear protein of the testis (NUT) carcinoma is a rare subset of poorly differentiated, highly aggressive malignancy defined by NUTM1 gene rearrangements.
Huahua Jiang +12 more
doaj +1 more source
NUT Carcinoma of the Sublingual Gland [PDF]
Head and Neck Pathology, 2015 NUT carcinoma (NC) is a recently described, rare and extremely aggressive cancer primarily located to supradiaphragmatic structures and affecting young individuals. NC is characterized by translocations involving the NUT gene on 15q14 with the most common translocation partner gene being BRD4 on 19p13, resulting in the t(15;19)(q14;p13) karyotype.
S. Andreasen +4 more
openaire +3 more sources
Frontiers in Oncology, 2023 BackgroundPrimary nuclear protein in testis (NUT) carcinoma is a rare malignant tumor originating from the salivary glands that usually occurs in midline structures, such as the head and neck, and has been identified in young patients. Progression of NUT
Shujuan Fu +6 more
doaj +1 more source
Challenges and Opportunities in NUT Carcinoma Research [PDF]
Genes, 2021 NUT carcinoma (NC) is a type of aggressive cancer driven by chromosome translocations. Fusion genes between a DNA-binding protein, such as bromodomain and extraterminal domain (BET) proteins, and the testis-specific protein NUTM1 generated by these translocations drive the formation of NC.
Bin Gu, Maxwell C. Hakun
openaire +2 more sources
Betel Nut and Arecoline: Past, Present, and Future Trends [PDF]
Innovations in Digital Health, Diagnostics, and Biomarkers, 2022 The areca nut, commonly known as betel nut, has been the subject of consistent scientific study over the past 5 decades. Betel nut is a natural compound chewed for its psychostimulating effects.
Zisis Kozlakidis +2 more
doaj +1 more source
Clinical Diagnosis and Treatment of Primary Lung NUT Midline Carcinoma
Zhongliu Fangzhi Yanjiu, 2019 The nuclear protein of the testis (NUT) midline carcinoma is a highly aggressive malignant epithelial neoplasm. The tumor is characterized by chromosome rearrangement of the NUT gene on 15q14, which results in the expression of NUT protein outside the ...
HE Xinyue, SHI Lei, ZHANG Ziyue, LI Jia
doaj +1 more source
A case of metastatic NUT carcinoma with prolonged response on gemcitabine and nab‐paclitaxel
Clinical Case Reports, 2021 Background NUT carcinoma is an aggressive malignancy characterized by translocations in the NUTM1 gene. There are currently no consensus treatment recommendations for NUT carcinomas.
Shetal A. Patel +5 more
doaj +1 more source
The first report of molecular characterized BRD4-NUT carcinoma in Brazil: a case report
Journal of Medical Case Reports, 2019 Background NUT midline carcinoma is a rare and aggressive subset of squamous cell carcinoma, which is characterized by the translocation of nuclear protein in testis gene that is mostly fused with bromodomain and extraterminal family proteins.
Leandro J. C. Oliveira +7 more
doaj +1 more source
Sinonasal NUT carcinoma: A retrospective case series from a single institution
Frontiers in Surgery, 2023 PurposeNuclear protein in testis (NUT) carcinoma is a rare, aggressive tumor defined by the presence of NUT gene rearrangement. The aim of this study was to describe the clinical, radiologic, and biological features of sinonasal NUT carcinoma.MethodsWe ...
Lei Wang +7 more
doaj +1 more source
Clinical imaging of primary pulmonary nucleoprotein of the testis carcinoma
Frontiers in Medicine, 2023 ObjectivePrimary pulmonary nucleoprotein of the testis (NUT) carcinoma is very rare in the clinic. In this study, the clinicopathological manifestations and imaging features of the primary pulmonary NUT carcinoma were investigated to improve the ...
Wenpeng Huang +6 more
doaj +1 more source