Results 11 to 20 of about 634,585 (195)
Primary Uterine NUT Carcinoma: A Case Report and Literature Review [PDF]
Clinics and PracticeBackground: Nuclear protein in testis (NUT) carcinoma is a rare, aggressive, and poorly differentiated epithelial malignancy characterized by the rearrangement of NUTM1 (NUT midline carcinoma family member 1) on 15q14.
Tetsuro Shiraishi +12 more
doaj +3 more sources
Leptomeningeal carcinomatosis in sinonasal NUT carcinoma: a case report and review of intracranial involvement [PDF]
Frontiers in OncologyBackgroundSinonasal NUT carcinoma is a rare and highly aggressive malignancy, frequently diagnosed at advanced stages with poor prognosis. Intracranial spread is uncommon and, to our knowledge, leptomeningeal carcinomatosis has not been previously ...
Francisco Manuel Rodríguez-Santiago +7 more
doaj +3 more sources
NUT Carcinoma—An Underdiagnosed Malignancy [PDF]
Frontiers in Oncology, 2022 NUT carcinoma (NC) is a rare and highly aggressive malignancy with a dismal prognosis and a median survival of 6–9 months only. Although very few cases of NC are reported each year, the true prevalence is estimated to be much higher, with NC potentially widely underdiagnosed due to the lack of awareness.
Ulrich M. Lauer +13 more
exaly +6 more sources
NUT carcinoma of the head and neck: A case report and literature review [PDF]
Precision Radiation OncologyNuclear protein in testis (NUT) carcinoma is a rare and highly aggressive cancer, characterized by rearrangements involving the NUT gene located on chromosome 15q14.
Yue Zhao +4 more
doaj +3 more sources
Challenging Diagnosis in NUT Carcinoma [PDF]
International Journal of Surgical Pathology, 2021 Nuclear protein in testis (NUT) carcinoma represents a highly aggressive, poorly differentiated carcinoma that is genetically defined by rearrangement of NUT gene. The histomorphological appearance ranges from entirely undifferentiated carcinoma to carcinoma with prominent squamous differentiation.
Grosse, Claudia, Grosse, Alexandra
openaire +5 more sources
Cancer Genetics and Cytogenetics, 2010 NUT midline carcinoma (NMC) is a rare, aggressive human cancer, genetically defined by rearrangements of the gene NUT (HUGO symbol: C15orf55). In the majority (∼75%) of NMCs, most of the coding sequence of NUT on chromosome 15q14 is fused with BRD4 creating chimeric genes that encode BRD-NUT fusion proteins. In the remaining cases, NUT is fused to BRD3
Christopher A. French
core +6 more sources
Molecular Characterization of NUT Carcinoma: A Report from the NUT Carcinoma Registry. [PDF]
Clin Cancer ResAbstract Purpose: NUT carcinoma (NC) is an underdiagnosed, poorly differentiated squamous cell cancer with a median survival of 6.7 months. Defined by NUTM1 fusions, NC enhances oncogene transcription, including MYC.
Kim JJ +16 more
europepmc +5 more sources
Supraglottic NUT Carcinoma: A Case Report and Literature Review
Case Reports in Oncology, 2022 Nuclear protein of the testis (NUT) carcinoma is a very rare cancer that occurs in relatively young patients. In this study, we experienced a case of laryngeal NUT carcinoma that followed a rapid course.
Masaaki Higashino +3 more
doaj +2 more sources
NUT Carcinoma of the Sublingual Gland [PDF]
Head and Neck Pathology, 2015 NUT carcinoma (NC) is a recently described, rare and extremely aggressive cancer primarily located to supradiaphragmatic structures and affecting young individuals. NC is characterized by translocations involving the NUT gene on 15q14 with the most common translocation partner gene being BRD4 on 19p13, resulting in the t(15;19)(q14;p13) karyotype.
S. Andreasen +4 more
openaire +4 more sources
Shared PRAME epitopes are T-cell targets in NUT carcinoma [PDF]
Journal for ImmunoTherapy of CancerBackground NUT carcinoma is a rare but highly lethal solid tumor without an effective standard of care. NUT carcinoma is caused by bromodomain-containing NUTM1 fusion oncogenes, most commonly BRD4::NUTM1.
Alex Rubinsteyn +22 more
doaj +2 more sources