Results 51 to 60 of about 9,420 (171)

A sample size analysis of a mathematical model of longitudinal tumor volume and progression‐free survival for Bayesian individual dynamic predictions in recurrent high‐grade glioma

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 495-509, March 2025.
Abstract Patients with recurrent high‐grade glioma (rHGG) have a poor prognosis with median progression‐free survival (PFS) of <7 months. Responses to treatment are heterogenous, suggesting a clinical need for prognostic models. Bayesian data analysis can exploit individual patient follow‐up imaging studies to adaptively predict the risk of progression.
Daniel J. Glazar   +5 more
wiley   +1 more source

NUT Midline Carcinoma of the Nasal Cavity [PDF]

open access: yesHead and Neck Pathology, 2016
Nuclear protein in testis (NUT) midline carcinoma (NMC) is a rare, aggressive, poorly differentiated form of squamous cell carcinoma caused by a chromosomal rearrangement of the NUT gene on chromosome 15. These tumors have a predilection for midline and paramidline structures of the upper aerodigestive tract and mediastinum and can affect patients ...
Mia, Edgar   +3 more
openaire   +2 more sources

A Retrospective Study of Two Mandibulectomy Approaches for T3‐Stage Lower Gingival Carcinoma

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective This study retrospectively analyzes two mandibular resection techniques for T3‐stage lower gingival carcinoma, aiming to compare their impact on patient prognosis. Methods Retrospective cohort study. Data from 78 cases of T3‐stage lower gingival carcinoma involving the mandible were reviewed in our Department of Head and Neck Surgery.
Hang Ling   +6 more
wiley   +1 more source

NUT carcinoma of the thorax in a 7-year-old child

open access: yesRadiology Case Reports, 2022
We present a rare case of NUT midline carcinoma of the thorax in a 7-year-old-male who presented with nonspecific abdominal pain. The patient was initially evaluated with an abdominal ultrasound, which was negative, followed by an abdominopelvic CT that ...
Kendall S. Cooper   +5 more
doaj   +1 more source

Voice of Asia: Provision of Patient‐Centered Care in Oral Cavity Cancer: A Qualitative Study With Patients, Caregivers, and Healthcare Professionals in Five Asia‐Pacific Regions

open access: yesAsia-Pacific Journal of Clinical Oncology, EarlyView.
The study identified key barriers to optimal patient‐centered care, including delayed diagnosis due to awareness and stigma‐related barriers among patients and caregivers, and opportunities to enhance multidisciplinary coordination. Resource limitations impacted nursing and psychosocial support, while access to support care varied across regions.
Edwin Pun Hui   +10 more
wiley   +1 more source

Tracheal resection and reconstruction under non-intubated anesthesia for nuclear protein in testis carcinoma: a case report

open access: yesWorld Journal of Surgical Oncology
Background Nuclear protein in testis (NUT) carcinoma is a rare and highly aggressive solid tumor with a poor overall survival outcome. There’s no recognized treatment or consensus on the management for NUT carcinoma.
Zijian Li   +5 more
doaj   +1 more source

Alpha–fetoprotein elevation in NUT midline carcinoma: a case report

open access: yesBMC Cancer, 2017
Background Nuclear protein in testis (NUT) midline carcinoma is a rarely diagnosed and potentially under-recognized type of squamous carcinoma that is considered one of the most aggressive human solid tumors.
Lorenzo D’Ambrosio   +7 more
doaj   +1 more source

Merkel Cell Carcinoma With Divergent Differentiation—Or Something Else? A Triphasic Cutaneous Carcinoma With Lineage Plasticity

open access: yesJournal of Cutaneous Pathology, EarlyView.
ABSTRACT Merkel cell carcinoma (MCC) is a rare, aggressive cutaneous neuroendocrine carcinoma that typically arises in sun‐exposed skin of older or immunosuppressed patients. Combined or collision tumors involving MCC and other cutaneous malignancies are uncommon, and tumors exhibiting more than two distinct malignant phenotypes are exceptionally rare.
Zeinab Khalil   +2 more
wiley   +1 more source

Novel BRD2::NUTM1 Fusion in NUT Carcinoma With Exceptional Response to Chemotherapy: A Case Report

open access: yesJTO Clinical and Research Reports
We present the first known case of a patient with BRD2::NUTM1-driven NUT carcinoma. A 59-year-old woman presented with poorly differentiated squamous cell lung cancer metastatic to the pleura.
Sarah J. Wu, MD, PhD   +10 more
doaj   +1 more source

NUT midline carcinoma in a young pregnant female: a case report

open access: yesWorld Journal of Surgical Oncology, 2020
Introduction The NUT midline carcinoma is a rare tumor mostly reported in the midline of upper aerodigestive tract and mediastinum. Children as well as adolescents are affected without a gender distribution. A standard treatment is not established.
Sebastian Joel   +4 more
doaj   +1 more source

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