Results 51 to 60 of about 9,223 (166)

Predominance of In‐Field Recurrence After Radiotherapy for Sinonasal Cancer: A Single‐Center Retrospective Study

Head &Neck, EarlyView.
ABSTRACT Background Sinonasal malignancies (SNM) are rare, heterogeneous tumors with poor prognosis. There is an unmet need to improve treatment outcomes. Despite advances in imaging and molecular classification, optimal curative radiotherapy (RT) strategies remain undefined.
M. de Ridder, L. J. van de Velde, T. de Bie, R. van Noortwijk, C. P. J. Raaijmakers, E. H. Voormolen, W. W. Braunius, R. de Bree, G. E. Breimer, L. A. Devriese, E. J. Smid, J. A. Rijken   +11 more
wiley   +1 more source

Systemic Treatments for Recurrent or Metastatic Sinonasal Carcinomas: A Retrospective Multicenter Study

Head &Neck, EarlyView.
ABSTRACT Introduction Sinonasal cancers are rare and heterogeneous and pose a therapeutic challenge at an advanced stage due to the lack of data on appropriate systemic management. Methods This retrospective multicenter study analyzed 83 patients with recurrent or metastatic sinonasal carcinomas ineligible for curative treatment, treated in France ...
Marie Degrange, Mathilde Morisseau, Justin Michel, Thibaut Reverdy, Sylvain Morinière, Amaury Daste, Maxime Humbert, Caroline Viala, Pauline Corbaux, Tiffany Darbas, François‐Régis Ferrand, Valentin Favier, Camille Evrard, Diane Evrard, Delphine Farneti, Sarah Betrian‐Lagarde, Victor Sarradin   +16 more
wiley   +1 more source

NUT carcinoma of the thorax in a 7-year-old child

Radiology Case Reports, 2022
We present a rare case of NUT midline carcinoma of the thorax in a 7-year-old-male who presented with nonspecific abdominal pain. The patient was initially evaluated with an abdominal ultrasound, which was negative, followed by an abdominopelvic CT that ...
Kendall S. Cooper, Nathan C. Hull, Kelly K. Horst, Amy B. Kolbe, Shannon N. Zingula, Paul G. Thacker   +5 more
doaj   +1 more source

Diagnosis of NUT Midline Carcinoma Using a NUT-specific Monoclonal Antibody [PDF]

American Journal of Surgical Pathology, 2009
NUT midline carcinoma (NMC) is a uniformly lethal malignancy that is defined by rearrangement of the nuclear protein in testis (NUT) gene on chromosome 15q14. NMCs are morphologically indistinguishable from other poorly differentiated carcinomas, and the diagnosis is usually made currently by fluorescence in situ hybridization (FISH).
Herbert, Haack, Laura A, Johnson, Christopher J, Fry, Katherine, Crosby, Roberto D, Polakiewicz, Edward B, Stelow, Seung-Mo, Hong, Brian E, Schwartz, Michael J, Cameron, Mark A, Rubin, Martin C, Chang, Jon C, Aster, Christopher A, French   +12 more
openaire   +2 more sources

Efficacy of omega‐3 fatty acids as a functional food: a multifaceted approach to health reinforcement

Journal of the Science of Food and Agriculture, EarlyView.
Abstract Omega‐3 fatty acids (omega‐3s) are polyunsaturated fatty acids linked with numerous health benefits. Omega‐3s exhibit multifaceted activities through various mechanisms. Eicosapentaenoic acid (EPA) alleviates oxidative stress by lowering reactive oxygen species and improving oxidative stress in brain tissues and acts against neurodegenerative ...
Md Faruque Ahmad, Abdulrahman A Alsayegh, Anjum Khanam, Awais Ahmed, António Raposo, Farkad Bantun, Md Zeyaullah, Ahmad O Babalghith, Abdullah F Aldairi, Boshra Mozaffar, Mohammed F Bajahzer, Mohamed H Abdelrahman, Mohammad Intakhab Alam   +12 more
wiley   +1 more source

NUT carcinoma: A rare presentation of a chest mass with hypercalcemia in a pediatric patient

Human Pathology Reports, 2023
The most common etiologies for chest masses in children include neurogenic tumors, germ cell tumors, leukemia/lymphoma and cysts [1]. Hypercalcemia of malignancy can complicate the clinical course, but is rare in children and most likely to occur in ...
Amanda K. Johnson, Travis Johnson, Katrina Winsnes, Jessica L. Davis   +3 more
doaj   +1 more source

Midline Carcinoma with NUT Rearrangement [PDF]

Otolaryngology–Head and Neck Surgery, 2012
Objective1) Report the clinicopathologic features of a rare, midline carcinoma. 2) Review the literature on NUT midline carcinoma and associated treatment protocols.MethodCase report with review of the literature on NUT midline carcinoma.ResultsA 23‐year‐old Chinese man presented with a 10‐day history of enlarging nontender cervical lymphadenopathy ...
Richard O. Wein, Kara Mosesso
openaire   +1 more source

Uric Acid in Metabolic Dysfunction‐Associated Steatotic Liver Disease

Portal Hypertension &Cirrhosis, EarlyView.
MASLD is the most prevalent chronic liver disease worldwide, yet effective pharmacological treatments remain limited. Hyperuricemia is now recognized as a key driver of hepatic steatosis, inflammation, and fibrosis, with elevated serum uric acid levels independently predicting hepatocellular carcinoma and liver‐related mortality.
Rong Wang, Zhenyu Liu, Jun Lin, Weijing Zhang, Xianzhi Liu, Tong Zhang   +5 more
wiley   +1 more source

Alpha–fetoprotein elevation in NUT midline carcinoma: a case report

BMC Cancer, 2017
Background Nuclear protein in testis (NUT) midline carcinoma is a rarely diagnosed and potentially under-recognized type of squamous carcinoma that is considered one of the most aggressive human solid tumors.
Lorenzo D’Ambrosio, Erica Palesandro, Marina Moretti, Giuseppe Pelosi, Alessandra Fabbri, Fabrizio Carnevale Schianca, Massimo Aglietta, Giovanni Grignani   +7 more
doaj   +1 more source

NUT midline carcinoma in a young pregnant female: a case report

World Journal of Surgical Oncology, 2020
Introduction The NUT midline carcinoma is a rare tumor mostly reported in the midline of upper aerodigestive tract and mediastinum. Children as well as adolescents are affected without a gender distribution. A standard treatment is not established.
Sebastian Joel, Friederike Weschenfelder, Ekkehard Schleussner, Gunther O. Hofmann, Wolfram Weschenfelder   +4 more
doaj   +1 more source