Results 71 to 80 of about 9,390 (183)

A rare case of NUT midline carcinoma

Gynecologic Oncology Case Reports, 2013
► NUT midline carcinoma is a rare and aggressive cancer arising in midline structures and is of squamous cell lineage. ► Diagnosis by use of molecular tests is possible with clinical suspicion. ► NUT midline carcinoma is refractory to conventional treatments, but understanding of molecular alterations may lead to an effective therapy.
Ball, Allison, Bromley, Amy, Glaze, Sarah, French, Christopher A., Ghatage, Prafull, Köbel, Martin   +5 more
openaire   +2 more sources

Voice of Asia: Provision of Patient‐Centered Care in Oral Cavity Cancer: A Qualitative Study With Patients, Caregivers, and Healthcare Professionals in Five Asia‐Pacific Regions

Asia-Pacific Journal of Clinical Oncology, EarlyView.
The study identified key barriers to optimal patient‐centered care, including delayed diagnosis due to awareness and stigma‐related barriers among patients and caregivers, and opportunities to enhance multidisciplinary coordination. Resource limitations impacted nursing and psychosocial support, while access to support care varied across regions.
Edwin Pun Hui, Puma Sundaresan, Hye Ryun Kim, Khoi Tuan Nguyen, Tracey E Nicholls, Hai‐Ling Teng, Yu‐Chung Li, Ying Jie Yew, Regina Gowindah, Con Stylianou, Pei‐Jen Lou   +10 more
wiley   +1 more source

Locally advanced thoracic NUT carcinoma — a case report and literature review

Oncology in Clinical Practice
NUT carcinoma is an extremely rare and aggressive cancer. It is characterised by the presence of a nuclear protein gene rearrangement (NUTM1) on chromosome 15q14. Nut carcinoma can occur at any age but mainly in third decade.
Piotr A. Chilczuk, Magdalena Knetki-Wróblewska   +1 more
doaj   +1 more source

The expanding universe of NUTM1 fusions in pediatric cancer

Clinical and Translational Science, 2023
NUT midline carcinoma family member 1 (NUTM1) fusions were originally identified in poorly differentiated and clinically aggressive carcinomas typically located in the midline structures of children and young adults, and collectively known as NUT ...
Rosane Charlab, Rebecca Racz
doaj   +1 more source

Evolving Pathology of Anaplastic Thyroid Carcinoma: Integrating Morphology, Immunohistochemistry, and Molecular Insights

Cancer Science, EarlyView.
Schematic overview of progression from differentiated thyroid carcinoma (DTC) to anaplastic thyroid carcinoma (ATC). ATC primarily develops via two pathways: the BRAF p.V600E‐mutated papillary thyroid carcinoma (PTC) pathway and the RAS‐mutated pathway. The origin and progression of BRAF/RAS‐wildtype ATC remain unclear.
Toru Odate, Tetsuo Kondo
wiley   +1 more source

Rare Secondary Neoplasms Arising in Epidermal Nevus: A Case Series and Literature Review

Journal of Cutaneous Pathology, EarlyView.
ABSTRACT Malignant transformation is known to occur with many nevi, such as nevus sebaceus. However, cases of secondary tumors developing in an epidermal nevus (EN) are rare, with only a few case reports documented in the literature. We present three unique cases of syringocystadenoma papilliferum (SCAP), syringofibroadenoma, trichilemmoma, and basal ...
Haya A. Homsi, Melissa Piliang, Jennifer Lucas, Jennifer S. Ko, Steven D. Billings, Shira Ronen   +5 more
wiley   +1 more source

Merkel Cell Carcinoma With Divergent Differentiation—Or Something Else? A Triphasic Cutaneous Carcinoma With Lineage Plasticity

Journal of Cutaneous Pathology, EarlyView.
ABSTRACT Merkel cell carcinoma (MCC) is a rare, aggressive cutaneous neuroendocrine carcinoma that typically arises in sun‐exposed skin of older or immunosuppressed patients. Combined or collision tumors involving MCC and other cutaneous malignancies are uncommon, and tumors exhibiting more than two distinct malignant phenotypes are exceptionally rare.
Zeinab Khalil, Hozaifa Elameen, Ahmed K. Alomari   +2 more
wiley   +1 more source

Head and neck squamous cell carcinoma in chronic areca nut chewing Indian women: Case series and review of literature

Indian Journal of Medical and Paediatric Oncology, 2012
Background: Head and neck squamous cell carcinoma (HNSCC) is an important public health problem in India. Several risk factors such as tobacco, human papilloma virus, alcohol, areca nut usage have been extensively studied as causative agents.
Sidramesh Shivanand Muttagi, Pankaj Chaturvedi, Rohith Gaikwad, Bikramjit Singh, Prashant Pawar   +4 more
doaj   +1 more source

Adverse Oral Health in Older Adults With Head and Neck Cancer (And Oral Potentially Malignant Disorders): A Systematic Review

Gerodontology, EarlyView.
ABSTRACT Objective This systematic review evaluated oral health, including oral health‐related quality of life (OHRQoL), in older adults with head and neck cancer (HANC) or oral potentially malignant disorders (OPMDs). The PICO/PECO focus question for this study was: ‘What is the incidence/prevalence of adverse oral health (O) among people aged 60 ...
Ciaran Moore, Niamh Walls, Shaima Abujaber, Amanda Willis, Finbarr Allen, Gerry McKenna   +5 more
wiley   +1 more source

Hilar/endobronchial NUT midline carcinoma: A case report

Human Pathology: Case Reports, 2017
Nuclear protein of the testis (NUT) midline carcinoma (NMC) is a rare aggressive tumor described in the midline in the chest and head and neck. Initially reported in younger individuals, it has subsequently been shown to have a wider age distribution ...
Deepika Sirohi, MD, Sumit Mamun, MD, FACP, Jaishree Jagirdar, MD   +2 more
doaj   +1 more source