Results 71 to 80 of about 9,223 (166)

Updates on Mediterranean diet and health status: active ingredients and pharmacological mechanisms

British Journal of Pharmacology, EarlyView.
The Mediterranean diet (MedDiet) is among the most extensively studied dietary patterns and has been consistently associated with reduced risk of all‐cause mortality, cardiovascular disease, metabolic disorders, cognitive decline and several types of cancers.
Lukas Schwingshackl, Jakub Morze, Sabina Wallerer, Georg Hoffmann   +3 more
wiley   +1 more source

Locally advanced thoracic NUT carcinoma — a case report and literature review

Oncology in Clinical Practice
NUT carcinoma is an extremely rare and aggressive cancer. It is characterised by the presence of a nuclear protein gene rearrangement (NUTM1) on chromosome 15q14. Nut carcinoma can occur at any age but mainly in third decade.
Piotr A. Chilczuk, Magdalena Knetki-Wróblewska   +1 more
doaj   +1 more source

The expanding universe of NUTM1 fusions in pediatric cancer

Clinical and Translational Science, 2023
NUT midline carcinoma family member 1 (NUTM1) fusions were originally identified in poorly differentiated and clinically aggressive carcinomas typically located in the midline structures of children and young adults, and collectively known as NUT ...
Rosane Charlab, Rebecca Racz
doaj   +1 more source

Comparative drug screening in NUT midline carcinoma [PDF]

British Journal of Cancer, 2014
The NUT midline carcinoma (NMC) is a rare but fatal cancer for which systematic testing of therapy options has never been performed.On the basis of disease biology, we compared the efficacy of the CDK9 inhibitor flavopiridol (FP) with a panel of anticancer agents in NMC cell lines and mouse xenografts.In vitro anthracyclines, topoisomerase inhibitors ...
Beesley, A H, Stirnweiss, A, Ferrari, E, Endersby, R, Howlett, M, Failes, T W, Arndt, G M, Charles, A K, Cole, C H, Kees, U R   +9 more
openaire   +2 more sources

Rare Secondary Neoplasms Arising in Epidermal Nevus: A Case Series and Literature Review

Journal of Cutaneous Pathology, EarlyView.
ABSTRACT Malignant transformation is known to occur with many nevi, such as nevus sebaceus. However, cases of secondary tumors developing in an epidermal nevus (EN) are rare, with only a few case reports documented in the literature. We present three unique cases of syringocystadenoma papilliferum (SCAP), syringofibroadenoma, trichilemmoma, and basal ...
Haya A. Homsi, Melissa Piliang, Jennifer Lucas, Jennifer S. Ko, Steven D. Billings, Shira Ronen   +5 more
wiley   +1 more source

Early‐Onset Oral Squamous Cell Carcinoma: Emerging Biological Insights, Risk Factors and Clinical Implications

Journal of Oral Pathology &Medicine, EarlyView.
ABSTRACT Background Early‐onset oral squamous cell carcinoma (EO‐OSCC), commonly defined as occurring in individuals under 50 years of age, is increasingly recognized as a potentially distinct clinical subset with differences in exposure patterns and tumor biology compared with conventional oral squamous cell carcinoma (OSCC).
Gennaro Musella, Cristina D'Antonio, Federica Canfora, Michele D. Mignogna, Valentino Vellone, Vito Carlo Alberto Caponio, Amerigo Giudice, Alessandro Villa, Daniela Adamo   +8 more
wiley   +1 more source

Head and neck squamous cell carcinoma in chronic areca nut chewing Indian women: Case series and review of literature

Indian Journal of Medical and Paediatric Oncology, 2012
Background: Head and neck squamous cell carcinoma (HNSCC) is an important public health problem in India. Several risk factors such as tobacco, human papilloma virus, alcohol, areca nut usage have been extensively studied as causative agents.
Sidramesh Shivanand Muttagi, Pankaj Chaturvedi, Rohith Gaikwad, Bikramjit Singh, Prashant Pawar   +4 more
doaj   +1 more source

NUT Midline Carcinoma of the Nasal Cavity [PDF]

Head and Neck Pathology, 2016
Nuclear protein in testis (NUT) midline carcinoma (NMC) is a rare, aggressive, poorly differentiated form of squamous cell carcinoma caused by a chromosomal rearrangement of the NUT gene on chromosome 15. These tumors have a predilection for midline and paramidline structures of the upper aerodigestive tract and mediastinum and can affect patients ...
Mia, Edgar, Andria M, Caruso, Esther, Kim, Robert D, Foss   +3 more
openaire   +2 more sources

Independent Multicentre Validation of the ‘Six‐Point’ Model for Malignant Transformation Risk in Oral Epithelial Dysplasia

Oral Diseases, EarlyView.
ABSTRACT Background Histological grading of oral epithelial dysplasia (OED) is used for predicting malignant transformation risk. However, grading is associated with significant subjectivity and observer variability leading to inconsistency in prognosis prediction.
Hanya Mahmood, Mike Bradburn, Nadim M. Islam, Omar Kujan, Nasir Rajpoot, Alan Roger Santos‐Silva, Pablo Agustin Vargas, Jacqueline James, Paul Nankivell, Hisham Mehanna, Syed Ali Khurram   +10 more
wiley   +1 more source

Hilar/endobronchial NUT midline carcinoma: A case report

Human Pathology: Case Reports, 2017
Nuclear protein of the testis (NUT) midline carcinoma (NMC) is a rare aggressive tumor described in the midline in the chest and head and neck. Initially reported in younger individuals, it has subsequently been shown to have a wider age distribution ...
Deepika Sirohi, MD, Sumit Mamun, MD, FACP, Jaishree Jagirdar, MD   +2 more
doaj   +1 more source