Results 111 to 120 of about 2,580 (202)

Pathogenesis and pathobiology of testicular germ cell tumours: a view from a developmental biological perspective with guidelines for pathological diagnostics

Histopathology, Volume 85, Issue 5, Page 701-715, November 2024.
Testicular germ cell tumours (GCT) are divided into three different subtypes according to their developmental origin, molecular features and histological differences. This review article summarises the pathobiological and developmental aspects of the three different types of testicular GCT that help in the histopathological examination of GCT by ...
Alexander Fichtner, Daniel Nettersheim, Felix Bremmer   +2 more
wiley   +1 more source

NUT Midline Carcinoma at the Anterior Skull Base - A Case Report

Medical Journal of Dr. D.Y. Patil Vidyapeeth
An uncommon and severe form of human malignancy is called NUT midline carcinoma (NMC). The mediastinum or midline of the upper aerodigestive tract contains the majority of NMCs.
Santosh K. Swain, S. P. A Anwer, Pradeep Pradhan, Amit K. Adhya   +3 more
doaj   +1 more source

Nut Directs p300-Dependent, Genome-Wide H4 Hyperacetylation in Male Germ Cells

Cell Reports, 2018
Summary: Nuclear protein in testis (Nut) is a universal oncogenic driver in the highly aggressive NUT midline carcinoma, whose physiological function in male germ cells has been unclear.
Hitoshi Shiota, Sophie Barral, Thierry Buchou, Minjia Tan, Yohann Couté, Guillaume Charbonnier, Nicolas Reynoird, Fayçal Boussouar, Matthieu Gérard, Mingrui Zhu, Lisa Bargier, Denis Puthier, Florent Chuffart, Ekaterina Bourova-Flin, Sarah Picaud, Panagis Filippakopoulos, Afsaneh Goudarzi, Ziad Ibrahim, Daniel Panne, Sophie Rousseaux, Yingming Zhao, Saadi Khochbin   +21 more
doaj   +1 more source

Selectivity on-target of bromodomain chemical probes by structure-guided medicinal chemistry and chemical biology [PDF]

, 2016
Targeting epigenetic proteins is a rapidly growing area for medicinal chemistry and drug discovery. Recent years have seen an explosion of interest in developing small molecules binding to bromodomains, the readers of acetyl-lysine modifications.
Alessio Ciulli, Carles Galdeano, Chiang C-M, Lejeune P   +3 more
core   +2 more sources

Prolonged Survival of NUT Midline Carcinoma and Current Approaches to Treatment. [PDF]

Oncologist, 2023
Kaplan HG, Subramaniam S, Vallières E, Barnett T.   +3 more
europepmc   +1 more source

A Rare Case of Lung Nuclear Protein in Testis Carcinoma

Acta Medica Bulgarica
Nuclear protein in testis carcinoma is a very rare but extremely aggressive highgrade carcinoma characterized by the presence of a fusion NUT gene – an oncogene. It is also called midline carcinoma because it mainly affects structures along the midline –
Ivanova S., Cherneva R., Alexieva M., Yankov G.   +3 more
doaj   +1 more source

A sinonasal NUT midline carcinoma in an 84-year-old man undergoing radiation and proton therapy. [PDF]

Clin Case Rep, 2023
Zhang K, Laxague F, MacMillan C, MacNeil SD, Fung K, Yoo J, Nichols AC, Mendez A.   +7 more
europepmc   +1 more source

NUT MIDLINE CARCINOMA: A FATAL NEOPLASM [PDF]

Chest, 2021
MARIAM SAEED, SARAH ELSAYED, ZINOBIA KHAN, AHMED GOHAR, MANI LATIFI   +4 more
openaire   +1 more source

NUT Midline Carcinoma: A Rare Solid Tumour Characterized by Chromosome Rearrangement. [PDF]

Evid Based Complement Alternat Med, 2022
Zhang H, Kong W, Liang W.
europepmc   +1 more source

Cerebral CIC-NUTM1 rearrangement sarcoma- case report and review of the literature

Frontiers in Oncology
BackgroundEwing sarcoma and Ewing-like sarcoma are both highly aggressive small round cell sarcomas, while CIC rearranged sarcoma (CRS), the most common specific type of Ewing-like sarcoma, exhibits a more aggressive course than Ewing sarcoma and ...
Wei Jin, Ke Dong, Fan Yang, Fan Yang, Jianning Zhang, Gang Cheng, Gang Cheng   +6 more
doaj   +1 more source