Rapid Progression of Primary Pulmonary NUT Midline Carcinoma: A Case Report and Literature Review. [PDF]
Respirol Case RepWe present the case of a patient with primary pulmonary nuclear protein in testis midline carcinoma, which is prone to misdiagnosis, who experienced poor treatment outcomes and a short overall survival duration. Anlotinib may provide an effective treatment option for select patient subgroups, and shortened chemotherapy could particularly benefit ...
Gao R, Yu J, Lv X, Dong C.
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Complex chromosomal rearrangements by single catastrophic pathogenesis in NUT midline carcinoma. [PDF]
Ann Oncol, 2017 Lee JK +13 more
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NUT Midline Carcinoma: A Rare Malignancy [PDF]
Cancer Control, 2017 Nuclear protein of the testis (NUT) midline carcinoma can present in the head, neck, and mediastinum. In general, it presents in young adult men and has a poor prognosis. We report on a case of NUT midline carcinoma of the mediastinum in a man 27 years of age without any prior malignancy.
Sameer, Al Diffalha +4 more
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NUT carcinoma of the thorax in a 7-year-old child
Radiology Case Reports, 2022 We present a rare case of NUT midline carcinoma of the thorax in a 7-year-old-male who presented with nonspecific abdominal pain. The patient was initially evaluated with an abdominal ultrasound, which was negative, followed by an abdominopelvic CT that ...
Kendall S. Cooper +5 more
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Sex determining region Y-box 2 (SOX2) amplification is an independent indicator of disease recurrence in sinonasal cancer. [PDF]
, 2013 The transcription factor SOX2 (3q26.3-q27) is an embryonic stem cell factor contributing to the induction of pluripotency in terminally differentiated somatic cells.
Agaimy, Abbas +14 more
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Nuclear protein in testis carcinoma of the lung
Translational Oncology, 2023 Nuclear protein in testis (NUT) carcinoma is a kind of highly aggressive and fatal solid tumor characterized by a rearrangement of the NUT carcinoma family member 1 (NUTM1) gene located on chromosome 15 q l4, where the most common form of fusion is BRD4 ...
Jing Chen, Meihui Li, Hongyang Lu
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Midline Carcinoma with NUT Rearrangement [PDF]
Otolaryngology–Head and Neck Surgery, 2012 Objective1) Report the clinicopathologic features of a rare, midline carcinoma. 2) Review the literature on NUT midline carcinoma and associated treatment protocols.MethodCase report with review of the literature on NUT midline carcinoma.ResultsA 23‐year‐old Chinese man presented with a 10‐day history of enlarging nontender cervical lymphadenopathy ...
Richard O. Wein, Kara Mosesso
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Intensive treatment and survival outcomes in NUT midline carcinoma of the head and neck. [PDF]
Cancer, 2016 Chau NG +14 more
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Comparative drug screening in NUT midline carcinoma [PDF]
British Journal of Cancer, 2014 The NUT midline carcinoma (NMC) is a rare but fatal cancer for which systematic testing of therapy options has never been performed.On the basis of disease biology, we compared the efficacy of the CDK9 inhibitor flavopiridol (FP) with a panel of anticancer agents in NMC cell lines and mouse xenografts.In vitro anthracyclines, topoisomerase inhibitors ...
Beesley, A H +9 more
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Radiologic Manifestations of Pulmonary Nuclear Protein in Testis Midline Carcinoma: A Case Report
Journal of the Korean Society of Radiology, 2023 Nuclear portein in testis (NUT) midline carcinoma is a very rare and low-differentiating malignant epithelial tumor that differentiates very aggressively and has poor prognosis. NUT midline carcinoma occurring in the lungs in particular can be confused
Jung A Kim +6 more
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