Results 121 to 130 of about 1,976,779 (364)

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Properties of Random Complex Chemical Reaction Networks and Their Relevance to Biological Toy Models

open access: yes, 2013
We investigate the properties of large random conservative chemical reaction networks composed of elementary reactions endowed with either mass-action or saturating kinetics, assigning kinetic parameters in a thermodynamically-consistent manner.
Bigan, Erwan   +2 more
core   +1 more source

The influence of macronutrients on cognitive performance : effects across age and task difficulty : thesis presented in partial fulfillment of the requirements for the degree of Master of Arts in Psychology at Massey University [PDF]

open access: yes, 2002
The effects of pure glucose, protein, and fat ingestion on tasks of paragraph recall, word recall, and mental arithmetic were examined. These effects were also investigated with regard to the age of the participant and the task difficulty level.
Culligan, Nicola
core  

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

open access: yesMolecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy   +9 more
wiley   +1 more source

Ion Exchange for Nutrient Recovery Coupled with Biosolids-Derived Biochar Pretreatment to Remove Micropollutants [PDF]

open access: yes, 2018
Wastewater, especially anaerobic treatment effluent, contains high ammonia nitrogen (NH4-N) and inorganic orthophosphate (PO4-P), which necessitate additional treatment to meet stringent discharge regulations.
Avila, Anna   +4 more
core   +1 more source

A Fungi-Driven Sustainable Circular Model Restores Saline Coastal Soils and Boosts Farm Returns

open access: yesHorticulturae
Agricultural production in the saline–alkaline soils of the Yellow River Delta faces persistent challenges in waste recycling and soil improvement. We developed a three-stage circular agriculture model integrating “crop straw–edible mushrooms–vegetables,”
Fei Bian   +9 more
doaj   +1 more source

Effects of long-term application of various organic amendments on soil particulate organic matter storage and chemical stabilisation of vertisol soil

open access: yesActa Agriculturae Scandinavica. Section B, Soil and Plant Science, 2018
Current understanding of the effects of long-term application of various organic amendments on soil particulate organic matter (POM) storage and chemical stabilisation remains limited. Therefore, we collected soil samples from the soil profile (0–100 cm)
Keke Hua, Daozhong Wang, Zhibin Guo
doaj   +1 more source

Multi‐omic profiling of squamous cell lung cancer identifies metabolites and related genes associated with squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Using multi‐omic characterization, we aimed to identify key regulators specific to squamous cell lung carcinoma (SqCC). SqCC‐specific differentially expressed genes were integrated with metabolics data. High expression of the creatine transporter SLC6A8, along with elevated creatine levels, appeared to be a distinct metabolic feature of SqCC.
Johan Staaf   +10 more
wiley   +1 more source

Responses of ectomycorrhizal fungi to mineral substrates [PDF]

open access: yes, 2003
Boreal forest soils are complex, heterogeneous growth substrates where organic and mineral components provide nutrient resources for soil organisms and plants. Mineral nutrients are cycled between living and dead organic components of the forest soil and
Rosling, Anna
core  

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