PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham+21 more
wiley +1 more source
Properties of Random Complex Chemical Reaction Networks and Their Relevance to Biological Toy Models
We investigate the properties of large random conservative chemical reaction networks composed of elementary reactions endowed with either mass-action or saturating kinetics, assigning kinetic parameters in a thermodynamically-consistent manner.
Bigan, Erwan+2 more
core +1 more source
The influence of macronutrients on cognitive performance : effects across age and task difficulty : thesis presented in partial fulfillment of the requirements for the degree of Master of Arts in Psychology at Massey University [PDF]
The effects of pure glucose, protein, and fat ingestion on tasks of paragraph recall, word recall, and mental arithmetic were examined. These effects were also investigated with regard to the age of the participant and the task difficulty level.
Culligan, Nicola
core
MONTHLY ABSORPTION OF NUTRIENTS FROM THE SOIL BY THE PERFECTION PIMIENTO PLANT [PDF]
H. L. Cochran, L. C. Olson
openalex +1 more source
YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy+9 more
wiley +1 more source
Ion Exchange for Nutrient Recovery Coupled with Biosolids-Derived Biochar Pretreatment to Remove Micropollutants [PDF]
Wastewater, especially anaerobic treatment effluent, contains high ammonia nitrogen (NH4-N) and inorganic orthophosphate (PO4-P), which necessitate additional treatment to meet stringent discharge regulations.
Avila, Anna+4 more
core +1 more source
A Fungi-Driven Sustainable Circular Model Restores Saline Coastal Soils and Boosts Farm Returns
Agricultural production in the saline–alkaline soils of the Yellow River Delta faces persistent challenges in waste recycling and soil improvement. We developed a three-stage circular agriculture model integrating “crop straw–edible mushrooms–vegetables,”
Fei Bian+9 more
doaj +1 more source
Current understanding of the effects of long-term application of various organic amendments on soil particulate organic matter (POM) storage and chemical stabilisation remains limited. Therefore, we collected soil samples from the soil profile (0–100 cm)
Keke Hua, Daozhong Wang, Zhibin Guo
doaj +1 more source
Using multi‐omic characterization, we aimed to identify key regulators specific to squamous cell lung carcinoma (SqCC). SqCC‐specific differentially expressed genes were integrated with metabolics data. High expression of the creatine transporter SLC6A8, along with elevated creatine levels, appeared to be a distinct metabolic feature of SqCC.
Johan Staaf+10 more
wiley +1 more source
Responses of ectomycorrhizal fungi to mineral substrates [PDF]
Boreal forest soils are complex, heterogeneous growth substrates where organic and mineral components provide nutrient resources for soil organisms and plants. Mineral nutrients are cycled between living and dead organic components of the forest soil and
Rosling, Anna
core