Results 141 to 150 of about 2,869,662 (402)

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

Volatile metabolomics highlights tea trichome's positive contribution to aroma and quality of white tea

Current Research in Food Science
Tea trichomes, rich in secondary metabolites, are hypothesized to significantly influence white tea aroma, yet their biochemical contributions remain unclear. This study investigated the volatile profiles of tea trichome and tea body across six white tea
Dandan Qi, Min Lu, Yali Shi, Xingmin Zhang, Lin Yue, Houzhen Jia, Chunwang Dong, Huimin Liu, Changbo Yuan   +8 more
doaj   +1 more source

VPS34-dependent control of apical membrane function of proximal tubule cells and nutrient recovery by the kidney

, 2022
Markus M. Rinschen, Jennifer L. Harder, Madalina E. Carter-Timofte, Luis Zanon Rodriguez, Carmen Mirabelli, Fatih Demir, Naziia Kurmasheva, Suresh Krishna Ramakrishnan, Madlen Kunke, Yifan Tan, A. Billing, Eileen Dahlke, Alexey Larionov, Wibke Bechtel‐Walz, Ute Aukschun, Marlen Grabbe, Rikke Nielsen, Erik Christensen, Matthias Kretzler, Tobias B. Huber, Christiane E. Wobus, David Olagnier, Gary Siuzdak, Florian Grahammer, Franziska Theilig   +24 more
openalex   +2 more sources

Assessing the Effects of Whey Hydrogel on Nutrient Stability in Soil and Yield of Leucosinapis alba and Hordeum vulgare [PDF]

, 2023
Jarmila Čechmánková, Vladimír Sedlařík, Silvie Duřpeková, Jan Drbohlav, Alexandra Šalaková, Radim Vácha   +5 more
openalex   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

Exploring the Use of High-Resolution Satellite Images to Estimate Corn Silage Yield Within Field

Remote Sensing
Corn (Zea mays L.) silage yield monitor data offer crucial insights into spatial and temporal yield variability. However, equipment’s sensor malfunctioning can result in data loss, and yield sensor systems are expensive to purchase and maintain.
Srinivasagan N. Subhashree, Manuel Marcaida, Shajahan Sunoj, Daniel R. Kindred, Laura J. Thompson, Quirine M. Ketterings   +5 more
doaj   +1 more source

Towards a breakthrough in nutrient recycling : State-of-the-art and recommendations for developing policy instruments in Finland [PDF]

, 2018
The report has been complemented on 11.9.2018This report describes the state-of-the-art in phosphorus and nitrogen recycling in Finland and looks at basic data on the volumes and geographical distribution of biomasses and their nutrients.
Grönroos, Juha, Iho, Antti, Kauppila, Jussi, Koikkalainen, Kauko, Koskiaho, Jari, Laine-Ylijoki, Jutta, Lantto, Raija, Lehtonen, Eeva, Luostarinen, Sari, Marttinen, Sanna, Oasmaa, Anja, Rasa, Kimmo, Sarvi, Minna, Tampio, Elina, Turtola, Eila, Valve, Helena, Venelampi, Olli, Ylivainio, Kari, zu Castell-Rüdenhausen, Malin   +18 more
core  

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

Responses of ectomycorrhizal fungi to changes in carbon and nutrient availability [PDF]

, 2001
Ectomycorrhizal (ECM) fungi may receive 20% of the total C fixed by their host plants and are essential components of host nutrient acquisition. As a consequence of the vast physiological diversity that exists among ECM fungi, changes in community ...
Fransson, Petra M.A.
core  

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source