Results 51 to 60 of about 71,254 (255)
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
ProceedingsBackground and objectives: Today, enough food is produced in the world, but much of the food produced and offered has poor nutritional quality, is unevenly distributed, or requires a lot of natural resources.
Marianne Hope Abel +6 more
doaj +1 more source
Nutrient profiling: comparison and critical analysis of existing systems [PDF]
Public Health Nutrition, 2006 AbstractBackgroundNutrient profiling systems aim at positioning foodstuffs relative to each other according to their contribution to a balanced diet. The accuracy and performance of methodologies are still debated. We present here a critical analysis of the structure and efficiency of the current schemes.MethodsThe literature survey detected only four ...
V, Azaïs-Braesco, C, Goffi, E, Labouze
openaire +2 more sources
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Metabolite Profiling of Chlamydomonas reinhardtii under Nutrient Deprivation [PDF]
Plant Physiology, 2005 Abstract A metabolite profiling technique for Chlamydomonas reinhardtii cells for multiparallel analysis of low-molecular weight polar compounds was developed. The experimental protocol was optimized to quickly inactivate enzymatic activity, achieve maximum extraction capacity, and process large sample quantities.
Christian, Bölling, Oliver, Fiehn
openaire +2 more sources
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Nutrient uptake under combined drought and salinity stress in hexaploid wheat species
Frontiers in Plant ScienceWheat is an important crop that often suffers from combined drought and salinity stress in agricultural fields, which adversely affects its growth, yield, and nutrient uptake.
Mohd. Kamran Khan
doaj +1 more source
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
Development and validation of the Meiji Nutritional Profiling System for children
Frontiers in NutritionBackgroundThe Meiji Nutritional Profiling System (Meiji NPS) takes into account life-stage differences and addresses specific health challenges in different age groups in Japan.ObjectivesThis study aimed to develop the Meiji NPS for younger (3–5 years ...
Ryota Wakayama +5 more
doaj +1 more source