Results 41 to 50 of about 896,214 (241)
IntroductionCanada promulgated mandatory front-of-pack labelling (FOPL) regulations in 2022, requiring pre-packaged foods meeting and/or exceeding recommended thresholds for nutrients-of-concern (i.e., saturated fat, sodium, sugars) to display a “high-in”
Jennifer J. Lee +9 more
doaj +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Sex-Specific Associations of Blood-Based Nutrient Profiling With Body Composition in the Elderly
The intake of adequate amounts and types of nutrients is key for sustaining health and a good quality of life, particularly in the elderly population.
Tobias Konz +17 more
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Background: The purpose of nutrient profiling models (NPM) is to evaluate and categorize food products, in order to make it easier for consumers to choose healthier options, to encourage the development of nutritious foods, and to restrict the excessive ...
Hung Nguyen Ngoc, Wantanee Kriengsinyos
doaj +1 more source
The implementation of mandatory front-of-pack nutrition labelling is currently being discussed in the European Union (EU). The Nutri-Score (NS) was developed in France to empower consumers to make informed and healthier food choices.
Edvina Hafner, Igor Pravst
doaj +1 more source
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
New Nutrient Rich Food Nutrient Density Models That Include Nutrients and MyPlate Food Groups
Background: Dietary guidelines have shifted emphasis from single nutrients to food patterns, food groups, and dietary ingredients. Nutrient profiling models need to do the same.Methods: Dietary intake data for 23,643 persons aged >2 years came from ...
Adam Drewnowski, Victor L. Fulgoni
doaj +1 more source

