Results 41 to 50 of about 81,239 (208)

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Newtools—Developing New Tools for a Sustainable Food System, Including Two Scoring Systems for Foods on Nutritional Quality and for Environmental and Social Sustainability

Proceedings
Background and objectives: Today, enough food is produced in the world, but much of the food produced and offered has poor nutritional quality, is unevenly distributed, or requires a lot of natural resources.
Marianne Hope Abel, Kaja Lund-Iversen, Hanne Fjerdingby Olsen, Helle Margrete Meltzer, Marianne Morseth, Trond Arild Ydersbond, Knut Inge Klepp   +6 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Nutrient uptake under combined drought and salinity stress in hexaploid wheat species

Frontiers in Plant Science
Wheat is an important crop that often suffers from combined drought and salinity stress in agricultural fields, which adversely affects its growth, yield, and nutrient uptake.
Mohd. Kamran Khan
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

FEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara, Kinga Skoczek, Elzbieta Pyza, Milena Damulewicz   +3 more
wiley   +1 more source

Development and validation of the Meiji Nutritional Profiling System for children

Frontiers in Nutrition
BackgroundThe Meiji Nutritional Profiling System (Meiji NPS) takes into account life-stage differences and addresses specific health challenges in different age groups in Japan.ObjectivesThis study aimed to develop the Meiji NPS for younger (3–5 years ...
Ryota Wakayama, Tao Yu, Adam Drewnowski, Satoshi Takasugi, Tomohito Horimoto, Chiharu Tsutsumi   +5 more
doaj   +1 more source

The extent, nature, and nutritional quality of foods advertised to children in Lebanon: the first study to use the WHO nutrient profile model for the Eastern Mediterranean Region

Food & Nutrition Research, 2019
Objective: Exposure to food marketing may influence children’s food preferences and consumption patterns and may increase the risk of childhood obesity.
Lara Nasreddine, Mandy Taktouk, Massar Dabbous, Jad Melki   +3 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source