Results 51 to 60 of about 896,214 (241)

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Racial & Identity Profiling Advisory Board Annual Report 2020 [PDF]

, 2018
California’s Racial and Identity Profiling Advisory Board (Board) is pleased to release its Third Annual Report. The Board was created by the Racial and Identity Profiling Act of 2015 (RIPA) to shepherd data collection and provide public reports with the
Racial & Identity Profiling Advisory Board
core  

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Evolution of the nutritional quality of packaged food supply in low- and middle-income countries following the implementation of a front-of-pack labeling scheme

Frontiers in Nutrition
IntroductionAs packaged foods consumption increases in low- and middle-income countries (LMICs), certain governments have introduced front-of-pack labeling (FOPL) schemes to promote healthier food choices.
Marie Tassy, Marie Tassy, Andreas Rytz, Alison L. Eldridge, Tsz Ning Mak, Frank Ekow Atta Hayford, Edith J. M. Feskens   +6 more
doaj   +1 more source

Methodology for the Determination of Fruit, Vegetable, Nut and Legume Points for Food Supplies without Quantitative Ingredient Declarations and Its Application to a Large Canadian Packaged Food and Beverage Database

Foods, 2020
Nutrient profiling (NP) models are useful tools for objectively and transparently quantifying the nutritional quality of packaged foods and beverages. Many NP models incorporate ingredients beneficial for health (e.g., fruits, vegetables, nuts, legumes ...
Laura Vergeer, Mavra Ahmed, Beatriz Franco-Arellano, Christine Mulligan, Kacie Dickinson, Jodi T. Bernstein, Marie-Ève Labonté, Mary R. L’Abbé   +7 more
doaj   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Nutrient density and affordability of aquatic foods in the FAO uFISH database assessed using Nutrient Rich Food (NRF) indices

Frontiers in Nutrition
BackgroundFish and shellfish are valuable sources of high-quality protein, vitamins, and minerals. Their nutrient density and price vary by species.ObjectivesThis study aimed to determine nutrient density and nutrient affordability per unit cost of fish ...
Emma Johnsson, Cristen Harris, Adam Drewnowski   +2 more
doaj   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Racial & Identity Profiling Advisory Board Annual Report 2020

, 2020
California’s Racial and Identity Profiling Advisory Board (Board) is pleased to release its Third Annual Report. The Board was created by the Racial and Identity Profiling Act of 2015 (RIPA) to shepherd data collection and provide public reports with the
Racial & Identity Profiling Advisory Board
core