Results 101 to 110 of about 526,165 (306)
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
A hydroponic design for microgravity and gravity installations [PDF]
A hydroponic system is presented that is designed for use in microgravity or gravity experiments. The system uses a sponge-like growing medium installed in tubular modules. The modules contain the plant roots and manage the flow of the nutrient solution.
Fielder, Judith, Leggett, Nickolaus
core +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Controlled ecological life support systems: Development of a plant growth module [PDF]
An effort was made to begin defining the scientific and technical requirements for the design and construction of a ground-based plant growth facility. In particular, science design criteria for the Plant Growth Module (PGM) of the Controlled Ecological ...
Averner, Mel M. +2 more
core +1 more source
Management of vegetable crop residues for reducing nitrate leaching losses in intensive vegetable rotations [PDF]
, 2012 Crop residues of field vegetables are often characterized by large amounts of biomass with a high N-content. Despite low soil temperatures during autumn, high rates of N mineralization and nitrification still occur causing important N-losses through ...
Agneessens, Laura +6 more
core +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
AnimalsThe objectives of this review are to identify the nutritional challenges faced by modern sows and present potential solutions to mitigate excessive maternal tissue loss and reproductive failure as it relates to recent genetic improvements.
Alexa Gormley +4 more
doaj +1 more source
Clostridioides difficile minimal nutrient requirements for flagellar motility. [PDF]
Front Microbiol, 2023 Schwanbeck J +3 more
europepmc +1 more source
Review of best management practices for aquatic vegetation control in stormwater ponds, wetlands, and lakes [PDF]
, 2013 Auckland Council (AC) is responsible for the development and operation of a stormwater network across the region to avert risks to citizens and the environment.
Champion, Paul +10 more
core
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source