Results 121 to 130 of about 526,165 (306)

How Nutrient Trading Could Help Restore the Chesapeake Bay [PDF]

open access: yes, 2010
The largest estuary in the United States, the Chesapeake Bay is a vital economic, cultural, and ecological resource for the region and the nation. Excess runoff and discharges of nutrients -- particularly nitrogen and phosphorus -- from farms, pavement ...
Cy Jones   +3 more
core  

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Energy and SID lysine partitioning in pigs weighing 32–196 kg, voluntarily fed diets differing in SID lysine content

open access: yesItalian Journal of Animal Science
This study investigated the partitioning of metabolisable energy (ME) and standardised ileal digestible (SID) lysine in 96 Goland-C21 × Camborough-43 pigs, raised from 32 to 196 kg of body weight (BW) and fed voluntarily diets containing low (L), medium ...
Stefano Schiavon   +10 more
doaj   +1 more source

Diet and activity in Swedish dogs [PDF]

open access: yes, 2001
In this thesis the demographics, diet and activity in a defined population of 460 insured Swedish dogs between 1 and 3 years was presented. The data was collected by using a mail and telephone questionnaire.
Sallander, Marie
core  

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

open access: yesFEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida   +6 more
wiley   +1 more source

Nutrient Requirements during Pregnancy and Lactation. [PDF]

open access: yesNutrients, 2021
Jouanne M   +3 more
europepmc   +1 more source

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